Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SSUD12_RS00395 Genome accession   NC_017621
Coordinates   67892..69073 (+) Length   393 a.a.
NCBI ID   WP_014637286.1    Uniprot ID   G7SIW4
Organism   Streptococcus suis D12     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 62892..74073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS00380 (SSUD12_0062) mutL 64475..66412 (+) 1938 WP_014637283.1 DNA mismatch repair endonuclease MutL -
  SSUD12_RS00385 (SSUD12_0063) ruvA 66442..67032 (+) 591 WP_014637284.1 Holliday junction branch migration protein RuvA -
  SSUD12_RS00390 (SSUD12_0064) - 67286..67855 (+) 570 WP_014637285.1 DNA-3-methyladenine glycosylase I -
  SSUD12_RS00395 (SSUD12_0065) cinA 67892..69073 (+) 1182 WP_014637286.1 competence/damage-inducible protein A Machinery gene
  SSUD12_RS00400 (SSUD12_0066) recA 69125..70276 (+) 1152 WP_014637287.1 recombinase RecA Machinery gene
  SSUD12_RS10855 - 70507..71800 (-) 1294 Protein_62 IS4 family transposase -
  SSUD12_RS00415 (SSUD12_0069) spx 72028..72426 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  SSUD12_RS00420 (SSUD12_0070) - 72526..72792 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  SSUD12_RS00425 (SSUD12_0071) ruvX 72792..73211 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  SSUD12_RS00430 (SSUD12_0072) - 73223..73543 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42928.80 Da        Isoelectric Point: 4.3670

>NTDB_id=49761 SSUD12_RS00395 WP_014637286.1 67892..69073(+) (cinA) [Streptococcus suis D12]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNENRLLSVLEVASQRSDLVILCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLSDLIDKQTDPTLAPYAKVGEVTLRLSTKAISQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=49761 SSUD12_RS00395 WP_014637286.1 67892..69073(+) (cinA) [Streptococcus suis D12]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAAAACAGGCTTCTGTCTGTACTGG
AAGTAGCCAGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCGAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGAT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAAGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGTCGGATTTGATTGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGATCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTTTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SIW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

96.947

100

0.969
  cinA Streptococcus mitis SK321

56.49

100

0.598
  cinA Streptococcus mitis NCTC 12261

56.25

100

0.595
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

42.175

95.929

0.405

Multiple sequence alignment