Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   IM723_RS08975 Genome accession   NZ_CP063275
Coordinates   1740211..1741311 (-) Length   366 a.a.
NCBI ID   WP_116920398.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain DMST-H2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1735211..1746311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IM723_RS08935 - 1735823..1736020 (-) 198 WP_014727723.1 helix-turn-helix transcriptional regulator -
  IM723_RS08940 - 1736269..1737462 (-) 1194 WP_014608740.1 acetate kinase -
  IM723_RS08945 comYH 1737518..1738474 (-) 957 WP_211836898.1 class I SAM-dependent methyltransferase Machinery gene
  IM723_RS08950 comGG 1738519..1738836 (-) 318 WP_141326604.1 competence type IV pilus minor pilin ComGG -
  IM723_RS08955 comYF 1738814..1739251 (-) 438 WP_022096897.1 competence type IV pilus minor pilin ComGF Machinery gene
  IM723_RS08960 comGE 1739235..1739528 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE -
  IM723_RS08965 comYD 1739500..1739928 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  IM723_RS08970 comYC 1739888..1740214 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  IM723_RS08975 comYB 1740211..1741311 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  IM723_RS08980 comGA/cglA/cilD 1741193..1742134 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  IM723_RS08985 - 1742215..1742577 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41797.91 Da        Isoelectric Point: 10.1084

>NTDB_id=494191 IM723_RS08975 WP_116920398.1 1740211..1741311(-) (comYB) [Streptococcus thermophilus strain DMST-H2]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=494191 IM723_RS08975 WP_116920398.1 1740211..1741311(-) (comYB) [Streptococcus thermophilus strain DMST-H2]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

54.678

93.443

0.511
  comYB Streptococcus mutans UA159

54.678

93.443

0.511
  comYB Streptococcus gordonii str. Challis substr. CH1

51.17

93.443

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.453

90.437

0.456
  comGB/cglB Streptococcus mitis SK321

49.697

90.164

0.448
  comGB/cglB Streptococcus pneumoniae Rx1

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae D39

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae R6

49.695

89.617

0.445
  comGB/cglB Streptococcus pneumoniae TIGR4

49.695

89.617

0.445
  comGB Lactococcus lactis subsp. cremoris KW2

45.758

90.164

0.413