Detailed information NTG0494188

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: IM723_RS08955
• Genome accession: NZ_CP063275
• Coordinates: 1738814..1739251 (-)
• Length: 145 a.a.
• NCBI ID: WP_022096897.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain DMST-H2
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1733814..1744251

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IM723_RS08920	-	1733880..1734542 (-)	663	WP_211836897.1	type II CAAX endopeptidase family protein	-
IM723_RS08925	-	1734639..1735028 (-)	390	WP_164135674.1	CAAX protease	-
IM723_RS10130	-	1735156..1735494 (-)	339	WP_224103197.1	CPBP family intramembrane glutamic endopeptidase	-
IM723_RS08935	-	1735823..1736020 (-)	198	WP_014727723.1	helix-turn-helix transcriptional regulator	-
IM723_RS08940	-	1736269..1737462 (-)	1194	WP_014608740.1	acetate kinase	-
IM723_RS08945	comYH	1737518..1738474 (-)	957	WP_211836898.1	class I SAM-dependent methyltransferase	Machinery gene
IM723_RS08950	comGG	1738519..1738836 (-)	318	WP_141326604.1	competence type IV pilus minor pilin ComGG	-
IM723_RS08955	comYF	1738814..1739251 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
IM723_RS08960	comGE	1739235..1739528 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
IM723_RS08965	comYD	1739500..1739928 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
IM723_RS08970	comYC	1739888..1740214 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
IM723_RS08975	comYB	1740211..1741311 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
IM723_RS08980	comGA/cglA/cilD	1741193..1742134 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
IM723_RS08985	-	1742215..1742577 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16375.89 Da
• Isoelectric Point: 8.9784

>NTDB_id=494188 IM723_RS08955 WP_022096897.1 1738814..1739251(-) (comYF) [Streptococcus thermophilus strain DMST-H2]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEGNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=494188 IM723_RS08955 WP_022096897.1 1738814..1739251(-) (comYF) [Streptococcus thermophilus strain DMST-H2]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGGGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae Rx1	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae R6	48.571	96.552	0.469
comGF/cglF	Streptococcus pneumoniae TIGR4	48.571	96.552	0.469
comGF/cglF	Streptococcus mitis NCTC 12261	46.809	97.241	0.455
comGF/cglF	Streptococcus mitis SK321	46.099	97.241	0.448
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441