Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LP316_RS00795 Genome accession   NZ_CP062946
Coordinates   187862..189091 (+) Length   409 a.a.
NCBI ID   WP_193022220.1    Uniprot ID   A0A7L9S6F5
Organism   Thalassotalea sp. LPB0316     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 182862..194091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LP316_RS00770 (LP316_00770) ampD 183342..183893 (-) 552 WP_193022216.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LP316_RS00775 (LP316_00775) - 183943..184464 (+) 522 WP_193022217.1 TIGR02281 family clan AA aspartic protease -
  LP316_RS00780 (LP316_00780) nadC 184465..185328 (+) 864 WP_193022218.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LP316_RS16100 (LP316_00785) - 185547..185972 (+) 426 WP_413470664.1 pilin -
  LP316_RS00790 (LP316_00790) pilB 186093..187793 (+) 1701 WP_193022219.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LP316_RS00795 (LP316_00795) pilC 187862..189091 (+) 1230 WP_193022220.1 type II secretion system F family protein Machinery gene
  LP316_RS00800 (LP316_00800) pilD 189212..190099 (+) 888 WP_193022221.1 prepilin peptidase Machinery gene
  LP316_RS00805 (LP316_00805) coaE 190125..190754 (+) 630 WP_193022222.1 dephospho-CoA kinase -
  LP316_RS00810 (LP316_00810) zapD 190853..191599 (+) 747 WP_193022223.1 cell division protein ZapD -
  LP316_RS00815 (LP316_00815) yacG 191680..191916 (+) 237 WP_193022224.1 DNA gyrase inhibitor YacG -
  LP316_RS00820 (LP316_00820) mutT 192016..192402 (-) 387 WP_193022225.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44242.04 Da        Isoelectric Point: 9.5383

>NTDB_id=492061 LP316_RS00795 WP_193022220.1 187862..189091(+) (pilC) [Thalassotalea sp. LPB0316]
MAVAKSKSAKPLDVFQWQGVNRKGKKISGELSAGSIMELKAQLRKQGVTPGRIKKKAKPLFGGDKKLTSADITTITRQIA
TMLGAGVPLVQTIEMIGKGHNNGNMQKLLGDIGTKLQAGSPLSECLREHPIHFDDLYCDLVHSGEQSGALETIFDRIATY
KEKAEALKAKIKKALTYPIAVIVIAIIVTSILLIFVVPTFKEIFDSFGAELPAFTMLVIKISEVMQSTWYLVLGGLFAFS
WAFKNAHRKNKNLRDTVDKNILKLPVVGDILHKAAIARYARTLATTFAAGVPLIDALESAAGASGNAVFRDAILDIRSEV
SSGMQMNLAMRNSNIFPDMVIQMVAIGEESGAVDDMLAKVATVYEQEVDNAVDNLTALLEPMIMAVLGIVIGGLIVAMYL
PIFQIGQVV

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=492061 LP316_RS00795 WP_193022220.1 187862..189091(+) (pilC) [Thalassotalea sp. LPB0316]
ATGGCTGTTGCTAAATCAAAAAGTGCAAAACCCCTCGATGTCTTTCAATGGCAAGGCGTTAACCGCAAGGGCAAAAAAAT
TAGCGGTGAGCTCTCAGCTGGCAGTATTATGGAGCTCAAAGCCCAACTGCGAAAGCAAGGTGTCACCCCAGGCCGTATTA
AGAAAAAAGCCAAACCTTTGTTTGGTGGCGATAAAAAGCTTACTTCAGCTGATATAACGACGATAACTAGACAAATTGCA
ACCATGCTAGGTGCTGGTGTGCCATTGGTACAAACTATCGAGATGATTGGTAAAGGCCATAATAACGGCAATATGCAAAA
ACTGCTGGGTGATATCGGCACTAAATTGCAAGCTGGCTCTCCGTTATCTGAGTGTCTTAGAGAGCACCCAATTCATTTTG
ATGATTTATATTGCGACTTAGTCCACTCGGGAGAGCAATCTGGTGCCTTAGAAACGATTTTTGATCGTATCGCCACCTAT
AAAGAAAAAGCCGAAGCACTCAAAGCAAAAATTAAGAAAGCATTAACTTACCCTATTGCCGTTATCGTGATTGCCATTAT
CGTAACGTCTATTTTACTTATCTTTGTTGTGCCGACCTTTAAAGAGATTTTTGATAGTTTTGGTGCAGAGCTTCCAGCTT
TTACTATGTTAGTAATCAAGATATCAGAAGTAATGCAGTCTACTTGGTATTTGGTACTCGGAGGGCTCTTTGCTTTTAGT
TGGGCTTTTAAAAACGCTCATCGTAAAAATAAAAACCTGCGTGACACTGTTGATAAAAACATTCTCAAGTTACCTGTAGT
TGGCGATATCCTGCACAAGGCCGCCATTGCGCGATATGCGCGAACATTAGCAACTACCTTTGCTGCTGGCGTCCCTTTAA
TTGATGCTTTAGAGTCTGCTGCCGGTGCCTCTGGCAATGCGGTATTTCGCGATGCTATTTTAGATATTCGCTCGGAAGTT
TCATCAGGTATGCAGATGAACTTGGCGATGCGCAACAGTAATATCTTCCCTGACATGGTCATTCAAATGGTTGCCATCGG
TGAAGAGTCGGGTGCCGTTGATGATATGCTTGCGAAAGTCGCTACCGTCTATGAGCAAGAGGTTGATAATGCGGTTGACA
ACCTAACCGCGCTATTAGAGCCGATGATCATGGCCGTACTCGGTATTGTTATCGGTGGTTTAATCGTTGCTATGTACTTA
CCTATTTTCCAAATAGGTCAAGTTGTTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(76-198)

Type II secretion system (T2SS), protein F (T2SSF)

(280-401)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L9S6F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

60.606

96.822

0.587
  pilC Acinetobacter baumannii D1279779

55.802

99.022

0.553
  pilC Acinetobacter baylyi ADP1

53.941

99.267

0.535
  pilC Legionella pneumophila strain ERS1305867

52.723

98.778

0.521
  pilC Vibrio cholerae strain A1552

44.828

99.267

0.445
  pilG Neisseria meningitidis 44/76-A

43.951

99.022

0.435
  pilG Neisseria gonorrhoeae MS11

43.704

99.022

0.433
  pilC Vibrio campbellii strain DS40M4

42.184

98.533

0.416