Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SGGB_RS11315 Genome accession   NC_017576
Coordinates   2288139..2289398 (-) Length   419 a.a.
NCBI ID   WP_009855166.1    Uniprot ID   A0AA36JZQ6
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2283139..2294398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS11290 (SGGB_2219) - 2284909..2285226 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  SGGB_RS11295 (SGGB_2220) ruvX 2285259..2285678 (-) 420 WP_009855163.1 Holliday junction resolvase RuvX -
  SGGB_RS11300 (SGGB_2221) - 2285675..2285944 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  SGGB_RS11305 (SGGB_2222) spx 2286267..2286665 (-) 399 WP_009855164.1 transcriptional regulator Spx -
  SGGB_RS11310 (SGGB_2223) recA 2286935..2288089 (-) 1155 WP_009855165.1 recombinase RecA Machinery gene
  SGGB_RS11315 (SGGB_2224) cinA 2288139..2289398 (-) 1260 WP_009855166.1 competence/damage-inducible protein A Machinery gene
  SGGB_RS11320 (SGGB_2225) - 2289530..2290720 (-) 1191 WP_009855167.1 MFS transporter -
  SGGB_RS12080 (SGGB_2226) - 2290880..2291053 (-) 174 WP_009855168.1 hypothetical protein -
  SGGB_RS11330 (SGGB_2227) - 2291103..2291567 (-) 465 WP_009855169.1 hypothetical protein -
  SGGB_RS11335 (SGGB_2228) - 2291637..2292044 (-) 408 WP_009855170.1 hypothetical protein -
  SGGB_RS11340 (SGGB_2229) - 2292207..2293061 (+) 855 WP_009855171.1 helix-turn-helix domain-containing protein -
  SGGB_RS11345 (SGGB_2230) ruvA 2293135..2293728 (-) 594 WP_009855172.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45489.79 Da        Isoelectric Point: 4.9032

>NTDB_id=48941 SGGB_RS11315 WP_009855166.1 2288139..2289398(-) (cinA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNDVTYVVLPGPPSELKPM
VLDSLVPLLSGDHKQLYSRVLRFFGIGESQLVTVLTDLIDNQTDPTIAPYAKTGEVTLRLSTKADDVASAKAKLDALEHK
ILAKKTLNSIPLEQLFYGYGDDNSMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLEDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=48941 SGGB_RS11315 WP_009855166.1 2288139..2289398(-) (cinA) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGACGTGACCTACGTTGTTCTCCCTGGACCGCCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTACCTTTATTGTCTGGAGACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTTTTGACAGATTTGATTGATAATCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGGCGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTATTTTATGGCTATGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACCATTACAGCGGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTGAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.662

99.523

0.723
  cinA Streptococcus mitis SK321

71.053

99.761

0.709
  cinA Streptococcus mitis NCTC 12261

70.813

99.761

0.706
  cinA Streptococcus pneumoniae Rx1

69.856

99.761

0.697
  cinA Streptococcus pneumoniae TIGR4

69.856

99.761

0.697
  cinA Streptococcus pneumoniae R6

69.856

99.761

0.697
  cinA Streptococcus pneumoniae D39

69.617

99.761

0.695
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

46.209

100

0.465

Multiple sequence alignment