Detailed information NTG0048098

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: NMBM01240355_RS03860
• Genome accession: NC_017517
• Coordinates: 763972..766191 (+)
• Length: 739 a.a.
• NCBI ID: WP_153063436.1
• Uniprot ID: -
• Organism: Neisseria meningitidis M01-240355
• Function: DNA processing; DNA transport into the cytoplasm (predicted from homology) DNA processing DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	762470..763477	763972..766191	flank	495

Gene organization within MGE regions

Location: 762470..766191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBM01240355_RS03855 (NMBM01240355_0700)	-	762470..763477 (-)	1008	WP_014581761.1	IS5 family transposase	-
NMBM01240355_RS03860 (NMBM01240355_0701)	comA	763972..766191 (+)	2220	WP_153063436.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene

Sequence

Protein

• Length: 739 a.a.
• Molecular weight: 79820.48 Da
• Isoelectric Point: 10.0892

>NTDB_id=48098 NMBM01240355_RS03860 WP_153063436.1 763972..766191(+) (comA) [Neisseria meningitidis M01-240355]
MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWWAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
GTVGADRVLLHGGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPSAVLGVGTWLSFGLVAALIWACSGRLHEGKRQTALRGQWAASVLSLVLLGYLFASLPLVSPLVNAVAIPWFSW
VLTPLALLGSVVPFAPLQQLGAFLAEYTLRFLVWLADVSPEFAVASAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVFYRSPGVPENEVAVTVWDAGQGLSVSVQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRGYKFYWQKKPFE

Nucleotide

• Length: 2220 bp

>NTDB_id=48098 NMBM01240355_RS03860 WP_153063436.1 763972..766191(+) (comA) [Neisseria meningitidis M01-240355]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGTGCGGCGGCTTCGTTCGCGCTGCCGGTCGTGCCGCATTGGCT
GTTTTGGCTGGCGGCTTTTGCGGTTTTTGCTGTGTTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGGACGGAGGCGGCATTGTCTTCCCAATGGTGGGCAGAAGCCGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGTGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGTGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGTG
TGCACCCTGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGAATAGGCGGCGCG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
TAATTGGCAGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTAATGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCTGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCAGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGCG
TTTTGATGTTGGCGGCGTTTGCGTGGGCTTGGCGCAGGGGAAGATTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCGTCGGCGGTCTTGGGTGTGGGGACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGCTCGGGGCGTTTGCACGAGGGAAAACGGCAAACTGCTTTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCGCTGG
TTTTGCTCGGTTATCTGTTTGCTTCGCTGCCTTTGGTCAGCCCTTTGGTCAATGCGGTGGCAATTCCGTGGTTTTCTTGG
GTATTGACGCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCTTTGCAACAGTTGGGGGCATTTTTGGCGGAATA
TACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCCGAGTTTGCCGTTGCCTCCGCACCTTTGCCGCTGTTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTGTTTTACCGTTCACCCGGCGTGCCGGAAAATGAGGTTGCGGTTACGGTTTGGGATGCGGGGCAGGGTTTGTCGGT
GTCGGTTCAGACGGCAAATCATCATCTTTTGTTTGACACCGGAACGGCAGCGGCGGCGCAGATGGGGATTGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGTTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTTGAGTTTTTGATGCCGTCTGAACGCAAAAACATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTCTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAACATCCGACCGAAGCGGTGCAGA
ACCGTGTCCGCGCACACGGCATCAAATTGCTGCGTACCGATTTGTCGGGCGCACTGCAATTCGGCTTGGGACGCGGCGGC
GTGAAGGCTCAACGTTTGAGAGGGTATAAATTCTATTGGCAGAAAAAACCGTTTGAATGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-465)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-677)

• Domain of unknown function (DUF4131) (DUF4131) (8-167)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Neisseria gonorrhoeae MS11	95.67	100	0.957