Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMBM01240355_RS04825 Genome accession   NC_017517
Coordinates   933885..934562 (+) Length   225 a.a.
NCBI ID   WP_002213841.1    Uniprot ID   E0N9M5
Organism   Neisseria meningitidis M01-240355     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 928885..939562
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBM01240355_RS04810 (NMBM01240355_0881) - 928943..929452 (+) 510 WP_002213852.1 isoprenylcysteine carboxyl methyltransferase family protein -
  NMBM01240355_RS04815 (NMBM01240355_0882) - 931420..932007 (-) 588 WP_014581927.1 superoxide dismutase -
  NMBM01240355_RS04820 (NMBM01240355_0883) dnaB 932170..933576 (+) 1407 WP_002213843.1 replicative DNA helicase -
  NMBM01240355_RS04825 (NMBM01240355_0884) pilH 933885..934562 (+) 678 WP_002213841.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NMBM01240355_RS04830 (NMBM01240355_0885) pilV 934586..935197 (+) 612 WP_041423359.1 type IV pilus modification protein PilV Machinery gene
  NMBM01240355_RS04835 (NMBM01240355_0886) pilJ 935194..936132 (+) 939 WP_041423360.1 PilW family protein Machinery gene
  NMBM01240355_RS04840 (NMBM01240355_0887) pilK 936111..936704 (+) 594 WP_014581931.1 pilus assembly protein Machinery gene
  NMBM01240355_RS04845 (NMBM01240355_0888) pilX 936709..937182 (+) 474 WP_014581932.1 PilX family type IV pilin Machinery gene
  NMBM01240355_RS04850 (NMBM01240355_0889) - 938446..938871 (-) 426 Protein_917 AzlC family ABC transporter permease -
  NMBM01240355_RS04855 (NMBM01240355_0890) dut 939013..939465 (+) 453 WP_014581934.1 dUTP diphosphatase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25183.79 Da        Isoelectric Point: 9.8985

>NTDB_id=48103 NMBM01240355_RS04825 WP_002213841.1 933885..934562(+) (pilH) [Neisseria meningitidis M01-240355]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTPN
NKCDSGKKGQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRGDRRTRRTMCQYK

Nucleotide


Download         Length: 678 bp        

>NTDB_id=48103 NMBM01240355_RS04825 WP_002213841.1 933885..934562(+) (pilH) [Neisseria meningitidis M01-240355]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGCCCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAAATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGGGGTG
ATCGGCGTACTCGGCGTACTATGTGCCAGTATAAATAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0N9M5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

83.036

99.556

0.827

Multiple sequence alignment