Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   NMAA_RS02025 Genome accession   NC_017512
Coordinates   401794..404079 (-) Length   761 a.a.
NCBI ID   WP_002244671.1    Uniprot ID   -
Organism   Neisseria meningitidis WUE 2594     
Function   pseudopilus extrusion and retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 396794..409079
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMAA_RS02005 (NMAA_0327) - 396966..397430 (-) 465 WP_002246402.1 transcriptional regulator NrdR -
  NMAA_RS02010 (NMAA_0328) - 397459..398301 (-) 843 WP_002222980.1 class II glutamine amidotransferase -
  NMAA_RS02015 (NMAA_0329) aroB 398945..400024 (-) 1080 WP_002236907.1 3-dehydroquinate synthase -
  NMAA_RS02020 (NMAA_0330) - 400104..400616 (-) 513 WP_002222978.1 shikimate kinase -
  NMAA_RS02025 (NMAA_0331) pilQ 401794..404079 (-) 2286 WP_002244671.1 type IV pilus secretin PilQ Machinery gene
  NMAA_RS02030 (NMAA_0332) pilP 404098..404643 (-) 546 WP_002214522.1 pilus assembly protein PilP Machinery gene
  NMAA_RS02035 (NMAA_0333) - 404661..405308 (-) 648 WP_002214521.1 type 4a pilus biogenesis protein PilO -
  NMAA_RS02040 (NMAA_0334) pilN 405309..405908 (-) 600 WP_002214520.1 PilN domain-containing protein Machinery gene
  NMAA_RS02045 (NMAA_0335) pilM 405911..407026 (-) 1116 WP_002246401.1 type IV pilus biogenesis protein PilM -

Sequence

Protein


Download         Length: 761 a.a.        Molecular weight: 81727.21 Da        Isoelectric Point: 10.0623

>NTDB_id=47849 NMAA_RS02025 WP_002244671.1 401794..404079(-) (pilQ) [Neisseria meningitidis WUE 2594]
MNTKLTKIISGLFVATAAFQTASAGNITDIKVSSLPNKQKIVKVSFDKEIVNPTGFVTSSPARIALDFEQTGISMDQQVL
EYADPLLSKISAAQNSSRARLVLNLNKPGQYNTEVRGNKVWIFINESDDTVSAPARPAVKAAPAAPAKQQAAAPSTKSAV
SVSEPFTPAKQQAAAPFTESVVSVSAPFSPAKQQAAASAKQQAAAPAKQQAAAPAKQTNIDFRKDGKNAGIIELAALGFA
GQPDISQQHDHIIVTLKNHTLPTTLQRSLDVADFKTPVQKVTLKRLNNDTQLIITTAGNWELVNKSAAPGYFTFQVLPKK
QNLESGGVNNAPKTFTGRKISLDFQDVEIRTILQILAKESGMNIVASDSVNGKMTLSLKDVPWDQALDLVMQARNLDMRQ
QGNIVNIAPRDELLAKDKAFLQAEKDIADLGALYSQNFQLKYKNVEEFRSILRLDNADTTGNRNTLVSGRGSVLIDPATN
TLIVTDTRSVIEKFRKLIDELDVPAQQVMIEARIVEAADGFSRDLGVKFGATGKKKLKNDTSAFGWGVNSGFGGDDKWGA
ETKINLPITAAANSISLVRAISSGALNLELSASESLSKTKTLANPRVLTQNRKEAKIESGYEIPFTVTSIANGGSSTNTE
LKKAVLGLTVTPNITPDGQIIMTVKINKDSPAQCASGNQTILCISTKNLNTQAMVENGGTLIVGGIYEEDNGNTLTKVPL
LGDIPVIGNLFKTRGKKTDRRELLIFITPRIMGTAGNSLRY

Nucleotide


Download         Length: 2286 bp        

>NTDB_id=47849 NMAA_RS02025 WP_002244671.1 401794..404079(-) (pilQ) [Neisseria meningitidis WUE 2594]
ATGAATACCAAACTGACAAAAATCATTTCCGGTCTCTTTGTCGCAACCGCCGCCTTTCAGACAGCATCGGCAGGAAACAT
TACAGACATCAAAGTTTCCTCCCTGCCCAACAAACAGAAAATCGTCAAAGTCAGCTTTGACAAAGAGATTGTCAACCCGA
CCGGCTTCGTAACCTCCTCACCGGCCCGCATCGCCTTGGACTTTGAACAAACCGGCATTTCCATGGATCAACAGGTACTC
GAATATGCCGATCCTCTGTTGAGCAAAATCAGTGCCGCACAAAACAGCAGCCGTGCGCGTCTGGTTCTGAATCTGAACAA
ACCGGGCCAATACAATACCGAAGTACGCGGGAACAAAGTTTGGATATTCATTAACGAATCGGACGATACCGTGTCCGCCC
CCGCACGCCCCGCCGTAAAAGCCGCGCCTGCCGCACCGGCAAAACAACAGGCTGCCGCACCGTCTACCAAGTCCGCAGTA
TCCGTATCCGAACCCTTTACCCCGGCAAAACAACAGGCTGCCGCACCGTTTACCGAGTCCGTAGTATCCGTATCCGCACC
GTTCAGCCCGGCAAAACAACAGGCGGCGGCATCAGCAAAACAACAGGCGGCAGCACCAGCAAAACAACAGGCGGCGGCAC
CAGCAAAACAAACCAATATCGATTTCCGCAAAGACGGCAAAAATGCCGGCATTATCGAATTGGCGGCATTGGGCTTTGCC
GGGCAGCCCGACATCAGCCAACAGCACGACCACATCATCGTTACGCTGAAAAACCATACCCTGCCGACCACGCTCCAACG
CAGTTTGGATGTGGCAGACTTTAAAACACCGGTTCAAAAGGTTACGCTGAAACGCCTCAATAACGACACCCAGCTGATTA
TCACAACAGCCGGCAACTGGGAACTCGTCAACAAATCCGCCGCGCCCGGATACTTTACCTTCCAAGTCCTGCCGAAAAAA
CAAAACCTCGAGTCAGGCGGCGTGAACAATGCGCCCAAAACCTTCACAGGCCGGAAAATCTCCCTTGACTTCCAAGATGT
CGAAATCCGCACCATCCTGCAGATTTTGGCAAAAGAATCCGGGATGAACATTGTTGCCAGCGACTCCGTCAACGGCAAAA
TGACCCTCTCCCTCAAAGACGTACCTTGGGATCAGGCTTTGGATTTGGTTATGCAGGCACGCAACCTCGATATGCGCCAA
CAAGGGAACATCGTCAACATCGCGCCCCGCGACGAGCTGCTTGCCAAAGACAAAGCCTTCTTACAGGCGGAAAAAGACAT
TGCCGATCTGGGCGCGCTGTATTCACAAAACTTCCAATTGAAATACAAAAATGTGGAAGAATTCCGCAGCATCCTGCGTT
TGGACAATGCCGACACAACCGGAAACCGCAATACGCTTGTCAGCGGCAGGGGCAGCGTGCTGATCGATCCCGCCACCAAT
ACCCTGATTGTTACCGATACCCGCAGCGTCATCGAAAAATTCCGCAAACTGATTGACGAATTGGACGTACCCGCGCAACA
AGTGATGATTGAGGCGCGTATCGTCGAAGCGGCAGACGGCTTCTCGCGCGATTTGGGCGTTAAATTCGGCGCGACAGGCA
AGAAAAAGCTGAAAAATGATACAAGCGCATTCGGCTGGGGGGTAAACTCCGGCTTCGGCGGCGACGATAAATGGGGGGCC
GAAACCAAAATCAACCTGCCGATTACCGCTGCCGCAAACAGCATTTCGCTGGTGCGCGCGATTTCCTCCGGTGCCTTGAA
TTTGGAATTGTCCGCATCCGAATCGCTTTCAAAAACCAAAACGCTTGCCAATCCGCGCGTGCTGACCCAAAACCGCAAAG
AGGCCAAAATCGAATCTGGTTACGAAATTCCTTTCACCGTAACCTCAATCGCGAACGGCGGCAGCAGCACGAACACGGAA
CTCAAAAAAGCCGTCTTGGGGCTGACCGTTACGCCGAACATCACGCCCGACGGCCAAATCATTATGACCGTCAAAATCAA
CAAGGACTCGCCTGCGCAATGTGCCTCCGGTAATCAGACGATTCTGTGTATTTCGACCAAAAACCTGAATACGCAGGCTA
TGGTTGAAAACGGCGGCACATTGATTGTCGGCGGTATTTATGAAGAAGACAACGGTAATACGCTGACCAAAGTCCCCCTG
TTGGGCGACATCCCCGTTATCGGCAACCTCTTTAAAACACGCGGGAAAAAAACCGACCGCCGCGAACTGCTGATTTTCAT
TACCCCGAGGATTATGGGTACGGCCGGCAACAGCCTGCGCTATTGA

Domains

Predicted by InterproScan.

Secretin and TonB N terminus short domain (STN)

(363-408)

Bacterial type II and III secretion system protein (Secretin)

(593-752)

Bacterial type II/III secretion system short domain (Secretin_N)

(436-507)

AMIN domain (AMIN)

(43-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Neisseria meningitidis MC58

98.7

100

0.997
  pilQ Neisseria meningitidis M1080

99.606

100

0.996
  pilQ Neisseria gonorrhoeae strain FA1090

90.933

100

0.909

Multiple sequence alignment