Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   H7790_RS00960 Genome accession   NZ_CP060645
Coordinates   151740..152678 (+) Length   312 a.a.
NCBI ID   WP_115230343.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1349     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146740..157678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7790_RS00950 (H7790_00950) rpoC 147489..151130 (+) 3642 WP_032460334.1 DNA-directed RNA polymerase subunit beta' -
  H7790_RS00955 (H7790_00955) - 151282..151647 (+) 366 WP_032460335.1 DUF1033 family protein -
  H7790_RS00960 (H7790_00960) comYA 151740..152678 (+) 939 WP_115230343.1 competence type IV pilus ATPase ComGA Machinery gene
  H7790_RS00965 (H7790_00965) comYB 152614..153648 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  H7790_RS00970 (H7790_00970) comYC 153650..153976 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  H7790_RS00975 (H7790_00975) comGD 153951..154379 (+) 429 WP_023605232.1 competence type IV pilus minor pilin ComGD -
  H7790_RS00980 (H7790_00980) comGE 154336..154620 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  H7790_RS00985 (H7790_00985) comYF 154613..155047 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  H7790_RS00990 (H7790_00990) comGG 155031..155357 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  H7790_RS00995 (H7790_00995) comYH 155455..156408 (+) 954 WP_115230344.1 class I SAM-dependent methyltransferase Machinery gene
  H7790_RS01000 (H7790_01000) - 156467..157663 (+) 1197 WP_030126459.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35072.38 Da        Isoelectric Point: 9.1037

>NTDB_id=477285 H7790_RS00960 WP_115230343.1 151740..152678(+) (comYA) [Streptococcus pyogenes strain TSPY1349]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQKA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YVRLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=477285 H7790_RS00960 WP_115230343.1 151740..152678(+) (comYA) [Streptococcus pyogenes strain TSPY1349]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAAAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGTAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

61.093

99.679

0.609
  comYA Streptococcus mutans UA159

61.093

99.679

0.609
  comYA Streptococcus gordonii str. Challis substr. CH1

60.45

99.679

0.603
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60

99.359

0.596
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae D39

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae R6

58.521

99.679

0.583
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

58.521

99.679

0.583
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.31

92.949

0.365