Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   H7792_RS08285 Genome accession   NZ_CP060643
Coordinates   1706795..1708066 (-) Length   423 a.a.
NCBI ID   WP_136284910.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY416     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1701795..1713066
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7792_RS08260 (H7792_08230) - 1703766..1704071 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7792_RS08265 (H7792_08235) ruvX 1704083..1704502 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7792_RS08270 (H7792_08240) - 1704499..1704768 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7792_RS08275 (H7792_08245) spx 1704881..1705279 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7792_RS08280 (H7792_08250) recA 1705570..1706706 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  H7792_RS08285 (H7792_08255) cinA 1706795..1708066 (-) 1272 WP_136284910.1 competence/damage-inducible protein A Machinery gene
  H7792_RS08290 (H7792_08260) - 1708135..1708695 (-) 561 WP_136098684.1 DNA-3-methyladenine glycosylase I -
  H7792_RS08295 (H7792_08265) ruvA 1708705..1709301 (-) 597 WP_002992186.1 Holliday junction branch migration protein RuvA -
  H7792_RS08300 (H7792_08270) - 1709303..1710523 (-) 1221 WP_032461237.1 MDR family MFS transporter -
  H7792_RS08305 (H7792_08275) mutL 1710534..1712516 (-) 1983 WP_228650343.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46006.78 Da        Isoelectric Point: 4.8322

>NTDB_id=477224 H7792_RS08285 WP_136284910.1 1706795..1708066(-) (cinA) [Streptococcus pyogenes strain TSPY416]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQT
LAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSISLPNKTGLAVGGFITVDGISYVVLPGPPSELKPM
VNEELVPLLSKQYSTLYSKVLRFFGIGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQ
LLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGLPLEELKLHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRLDV
RYIATLHAFNMVRKTLLKLENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=477224 H7792_RS08285 WP_136284910.1 1706795..1708066(-) (cinA) [Streptococcus pyogenes strain TSPY416]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGACAACGAGGAGCGTTTACTTTCAGTGATTA
CAACTGCTAGTCAGCGTAGTGACTTGGTGATTTTATGTGGTGGCCTTGGTCCAACGAAAGATGATTTAACCAAACAAACT
TTAGCAAAGTACCTTAGGAAAGACTTGGTTTATGATGAGCAAGCTTGTCAGAAACTAGATGACTTTTTTGCTAAGCGCAA
GCCTTCATCACGGACACCAAATAATGAGCGACAGGCACAAGTGATTGAAGGGTCAATCTCTTTGCCAAATAAAACTGGTC
TTGCGGTTGGTGGGTTCATCACAGTCGATGGTATTAGTTATGTTGTCTTACCGGGTCCTCCAAGTGAATTGAAGCCGATG
GTAAATGAAGAATTGGTACCACTTCTGTCAAAACAATACAGTACATTGTATTCAAAGGTACTACGCTTTTTTGGTATTGG
GGAAAGTCAGTTGGTAACAGTCTTGTCAGATTTTATTGAGAATCAAACTGATCCAACCATTGCTCCGTATGCTAAGACTG
GCGAAGTGACTCTTCGCTTATCAACAAAAACTGAAAACCAAGCTCTGGCAGATAAAAAGTTAGGTCAGCTAGAAGCGCAG
CTACTATCCCGAAAAACTCTTGAAGGTCAACCCTTAGCTGATGTCTTTTATGGCTATGGGGAGGATAATTCCTTAGCGCG
TGAGACATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCCTTCCTTTAGAGGAGTTGAAATTGCATGGCGTTGTTAGTGCTTATACAGCCGAGGGGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGTCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGTCGTTTGGATGTG
CGCTATATCGCTACTTTACATGCCTTTAATATGGTCCGTAAAACTTTATTAAAACTTGAGAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

69.74

100

0.697
  cinA Streptococcus mitis SK321

69.784

98.582

0.688
  cinA Streptococcus mitis NCTC 12261

69.305

98.582

0.683
  cinA Streptococcus pneumoniae TIGR4

68.345

98.582

0.674
  cinA Streptococcus pneumoniae Rx1

68.345

98.582

0.674
  cinA Streptococcus pneumoniae R6

68.345

98.582

0.674
  cinA Streptococcus pneumoniae D39

68.106

98.582

0.671
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461