Detailed information NTG0464595

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: HZR12_RS06730
• Genome accession: NZ_CP058615
• Coordinates: 1313653..1313964 (+)
• Length: 103 a.a.
• NCBI ID: WP_000472256.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain 110900
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1308653..1318964

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HZR12_RS06700 (HZR12_06700)	-	1309436..1309639 (+)	204	WP_000087561.1	YqgQ family protein	-
HZR12_RS06705 (HZR12_06705)	-	1309636..1310622 (+)	987	WP_000161314.1	ROK family glucokinase	-
HZR12_RS06710 (HZR12_06710)	-	1310622..1310951 (+)	330	WP_001018871.1	MTH1187 family thiamine-binding protein	-
HZR12_RS06715 (HZR12_06715)	-	1310948..1311571 (+)	624	WP_001223008.1	MBL fold metallo-hydrolase	-
HZR12_RS06720 (HZR12_06720)	comGA	1311623..1312597 (+)	975	WP_000697228.1	competence type IV pilus ATPase ComGA	Machinery gene
HZR12_RS06725 (HZR12_06725)	comGB	1312569..1313639 (+)	1071	Protein_1282	competence type IV pilus assembly protein ComGB	-
HZR12_RS06730 (HZR12_06730)	comGC	1313653..1313964 (+)	312	WP_000472256.1	competence type IV pilus major pilin ComGC	Machinery gene
HZR12_RS06735 (HZR12_06735)	comGD	1313942..1314388 (+)	447	WP_001790850.1	competence type IV pilus minor pilin ComGD	Machinery gene
HZR12_RS06740 (HZR12_06740)	comGE	1314375..1314674 (+)	300	WP_000844413.1	hypothetical protein	Machinery gene
HZR12_RS06745 (HZR12_06745)	comGF	1314592..1315089 (+)	498	WP_001789864.1	competence type IV pilus minor pilin ComGF	Machinery gene
HZR12_RS06750 (HZR12_06750)	-	1315186..1315332 (+)	147	WP_001789879.1	hypothetical protein	-
HZR12_RS06755 (HZR12_06755)	-	1315322..1315846 (+)	525	WP_001015117.1	shikimate kinase	-
HZR12_RS06760 (HZR12_06760)	gcvT	1316005..1317096 (+)	1092	WP_000093349.1	glycine cleavage system aminomethyltransferase GcvT	-
HZR12_RS06765 (HZR12_06765)	gcvPA	1317116..1318462 (+)	1347	WP_048665334.1	aminomethyl-transferring glycine dehydrogenase subunit GcvPA	-

Sequence

Protein

• Length: 103 a.a.
• Molecular weight: 11315.36 Da
• Isoelectric Point: 8.5268

>NTDB_id=464595 HZR12_RS06730 WP_000472256.1 1313653..1313964(+) (comGC) [Staphylococcus aureus strain 110900]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide

• Length: 312 bp

>NTDB_id=464595 HZR12_RS06730 WP_000472256.1 1313653..1313964(+) (comGC) [Staphylococcus aureus strain 110900]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (6-30)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Staphylococcus aureus MW2	100	100	1
comGC	Staphylococcus aureus N315	100	100	1
comGC/cglC	Streptococcus pneumoniae TIGR4	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae Rx1	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae D39	46.078	99.029	0.456
comGC/cglC	Streptococcus pneumoniae R6	46.078	99.029	0.456
comGC/cglC	Streptococcus mitis SK321	51.163	83.495	0.427
comGC/cglC	Streptococcus mitis NCTC 12261	51.163	83.495	0.427
comYC	Streptococcus gordonii str. Challis substr. CH1	42.857	95.146	0.408
comYC	Streptococcus suis isolate S10	50	75.728	0.379
comGC	Bacillus subtilis subsp. subtilis str. 168	41.758	88.35	0.369
comGC	Lactococcus lactis subsp. cremoris KW2	46.341	79.612	0.369