Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HW271_RS00605 Genome accession   NZ_CP058258
Coordinates   124729..125985 (+) Length   418 a.a.
NCBI ID   WP_178894463.1    Uniprot ID   A0A7H8Z6D3
Organism   Streptococcus sp. oral taxon 061 strain F0704     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 119729..130985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HW271_RS00580 (HW271_00580) - 120125..120937 (-) 813 WP_178894458.1 Cof-type HAD-IIB family hydrolase -
  HW271_RS00585 (HW271_00585) - 121134..122555 (+) 1422 WP_178894459.1 NCS2 family permease -
  HW271_RS00590 (HW271_00590) tsaE 122644..123087 (+) 444 WP_178894460.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  HW271_RS00595 (HW271_00595) - 123077..123598 (+) 522 WP_178894461.1 GNAT family N-acetyltransferase -
  HW271_RS00600 (HW271_00600) brpA 123603..124652 (+) 1050 WP_254730020.1 biofilm formation/cell division transcriptional regulator BrpA -
  HW271_RS00605 (HW271_00605) cinA 124729..125985 (+) 1257 WP_178894463.1 competence/damage-inducible protein A Machinery gene
  HW271_RS00610 (HW271_00610) recA 126040..127188 (+) 1149 WP_178894464.1 recombinase RecA Machinery gene
  HW271_RS00615 (HW271_00615) - 127234..127788 (-) 555 WP_178894465.1 GNAT family N-acetyltransferase -
  HW271_RS00620 (HW271_00620) - 127897..129267 (+) 1371 WP_178894466.1 MATE family efflux transporter -
  HW271_RS00625 (HW271_00625) - 129364..130080 (+) 717 WP_006146163.1 YebC/PmpR family DNA-binding transcriptional regulator -
  HW271_RS00630 (HW271_00630) - 130126..130809 (-) 684 WP_178894467.1 hypothetical protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45149.45 Da        Isoelectric Point: 4.7474

>NTDB_id=463199 HW271_RS00605 WP_178894463.1 124729..125985(+) (cinA) [Streptococcus sp. oral taxon 061 strain F0704]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIAKNRSNLVILTGGLGPTEDDLTKQT
LAHFLGRDLTFDAQAQAKLDEFFAHRPDYARTPNNERQAQIVEGSIPLPNETGLAVGGMIEVAGVTYVVLPGPPSELKPM
VLNELLPRLTTGAKLYSRVLRFFGIGESQLVTILSDLIEEQTDPTLAPYAKTGEVTLRLSTKATSQEEARKSLDRLEVQI
LARQTFEGVALKDICYGYGEETSLASVVVEELKKQHKTITAVESLTAGLFQATLADFSGVSAIFKGGFVTYSLEEKAKIL
DIPREELEEHGVVSAYTAEKMAEQSRLKTQSDFGVSLTGVAGPDSLEGHPAGTVFIGLSQASGTEVVQVNIAGRSRADVR
KIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=463199 HW271_RS00605 WP_178894463.1 124729..125985(+) (cinA) [Streptococcus sp. oral taxon 061 strain F0704]
ATGAAAGCGGAAATCATAGCTGTTGGAACAGAGATTCTAACAGGTCAAATTGTCAATACCAATGCTCAGTTTTTATCTGA
AAAGTTGGCTGAAATCGGTGTTGATGTCTACTTCCAAACGGCTGTAGGTGATAATGAGGCTCGTCTCTTATCCTTGTTGG
AGATTGCTAAGAATCGTAGCAATCTGGTTATCCTAACAGGAGGATTGGGACCGACAGAGGATGATTTGACCAAACAAACC
TTGGCCCATTTTCTAGGGCGTGATTTAACTTTTGATGCTCAAGCACAGGCTAAGCTAGATGAGTTTTTTGCTCATCGACC
GGACTATGCCCGAACTCCAAATAATGAACGCCAAGCTCAAATCGTTGAGGGTTCGATCCCGCTACCTAATGAAACAGGAC
TAGCAGTCGGAGGCATGATTGAGGTAGCTGGCGTGACCTATGTCGTCCTACCAGGGCCGCCAAGTGAACTGAAACCCATG
GTTTTAAATGAACTGTTGCCAAGATTGACAACTGGAGCTAAGTTGTACTCACGTGTGCTTCGTTTCTTTGGCATTGGGGA
GAGCCAGCTAGTAACGATTCTATCGGATTTGATTGAAGAGCAGACAGATCCAACCTTGGCCCCTTATGCAAAAACGGGAG
AAGTGACTCTGCGTTTGTCTACCAAGGCTACTAGTCAAGAAGAAGCAAGAAAATCTTTGGATCGTCTTGAGGTTCAAATT
CTTGCCCGCCAGACTTTTGAAGGTGTTGCTTTAAAGGATATTTGCTATGGTTATGGTGAGGAAACGAGTCTAGCTAGTGT
AGTTGTTGAGGAGTTGAAAAAGCAGCATAAAACCATAACGGCTGTGGAAAGTTTGACAGCAGGGCTTTTTCAAGCAACTC
TTGCAGACTTTTCGGGAGTGTCAGCTATCTTCAAAGGTGGTTTTGTCACATATAGTCTAGAAGAAAAAGCTAAGATATTA
GACATCCCTCGAGAAGAGTTGGAAGAACATGGAGTCGTGTCAGCGTATACAGCGGAAAAAATGGCAGAGCAATCACGGCT
TAAAACCCAGTCGGACTTTGGAGTTAGCTTGACAGGTGTGGCTGGTCCGGATAGTCTAGAAGGGCATCCTGCAGGTACAG
TTTTTATCGGTTTGTCTCAAGCATCAGGCACTGAAGTTGTTCAGGTCAATATAGCTGGAAGAAGTCGAGCAGATGTTCGT
AAAATTGCAGTCATGCATGCTTTTAACTTAGTTCGCAAAGCTTTATTAAGTGACTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8Z6D3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

85.646

100

0.856
  cinA Streptococcus mitis NCTC 12261

85.167

100

0.852
  cinA Streptococcus pneumoniae TIGR4

84.45

100

0.845
  cinA Streptococcus pneumoniae Rx1

84.211

100

0.842
  cinA Streptococcus pneumoniae R6

84.211

100

0.842
  cinA Streptococcus pneumoniae D39

83.971

100

0.84
  cinA Streptococcus mutans UA159

72.249

100

0.722
  cinA Streptococcus suis isolate S10

55.769

99.522

0.555
  cinA Bacillus subtilis subsp. subtilis str. 168

46.411

100

0.464