Detailed information NTG0046089

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LILO_RS05835
• Genome accession: NC_020450
• Coordinates: 1204290..1205138 (+)
• Length: 282 a.a.
• NCBI ID: WP_015426410.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis IO-1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1199290..1210138

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LILO_RS05810 (lilo_1114)	ilvN	1200047..1200523 (+)	477	WP_015426405.1	acetolactate synthase small subunit	-
LILO_RS05815 (lilo_1115)	ilvC	1200569..1201591 (+)	1023	WP_015426406.1	ketol-acid reductoisomerase	-
LILO_RS05820 (lilo_1116)	ilvA	1201647..1202897 (+)	1251	WP_015426407.1	threonine ammonia-lyase IlvA	-
LILO_RS05825 (lilo_1117)	budA	1203013..1203723 (+)	711	WP_015426408.1	acetolactate decarboxylase	-
LILO_RS05830 (lilo_1118)	-	1203764..1204144 (+)	381	WP_015426409.1	RidA family protein	-
LILO_RS05835 (lilo_1119)	dprA	1204290..1205138 (+)	849	WP_015426410.1	DNA-processing protein DprA	Machinery gene
LILO_RS05840 (lilo_1120)	topA	1205400..1207532 (+)	2133	WP_015426411.1	type I DNA topoisomerase	-
LILO_RS05845 (lilo_1121)	trmFO	1207604..1208947 (+)	1344	WP_003131150.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
LILO_RS05850 (lilo_1122)	xerS	1208992..1210062 (-)	1071	WP_015426412.1	tyrosine recombinase XerS	Machinery gene

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 32159.28 Da
• Isoelectric Point: 9.5086

>NTDB_id=46089 LILO_RS05835 WP_015426410.1 1204290..1205138(+) (dprA) [Lactococcus lactis subsp. lactis IO-1]
MITNFDLYRWKKAGMTNLGVNKLLKFFHRYDKKISLRQMGQVAQLKSIPNFIEQYKNQDIIKLREEYKIYPSFSLLDEIY
PERLKEIYNPPVLLFYQGDIRLLKTPKLAFVGSRQASSQGIKAVQKIVTELNQNFTIVSGLAKGIDTASHLSAIKNKIPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLILSEYSVGEKPLRYHFPERNRIIAGLSHGVVVIEAKLRSGSLITCERALEEG
RDIFAVPGNIADGFSDGCNHLIQQGAKLIYQAQDILEEYLYD

Nucleotide

• Length: 849 bp

>NTDB_id=46089 LILO_RS05835 WP_015426410.1 1204290..1205138(+) (dprA) [Lactococcus lactis subsp. lactis IO-1]
ATGATAACAAATTTTGATTTATATCGTTGGAAAAAAGCTGGCATGACCAATTTAGGAGTAAATAAACTTTTAAAATTTTT
TCATAGATATGATAAAAAAATAAGTTTAAGACAAATGGGACAAGTAGCACAACTTAAATCAATTCCCAACTTTATTGAAC
AATATAAAAATCAAGACATAATTAAACTGAGAGAAGAGTATAAAATATACCCATCATTTTCTCTTCTTGATGAAATTTAT
CCCGAAAGGCTCAAGGAAATTTACAATCCACCTGTTCTATTATTTTATCAAGGAGATATAAGACTCTTAAAAACTCCTAA
ATTAGCTTTTGTTGGTAGTCGACAAGCAAGCTCACAAGGAATTAAAGCCGTTCAAAAAATTGTGACAGAGTTGAACCAAA
ATTTTACGATTGTCAGCGGACTCGCTAAAGGAATTGATACAGCAAGTCATCTTTCTGCCATTAAAAATAAAATCCCTACA
ATTGCAGTTATCGGTACAGGCTTAGATATCTTTTATCCTTTAGAAAATCGAAAAATTCAAGAATATCTTGCTAAAAACCA
ACTAATTCTATCAGAATATTCAGTCGGAGAAAAACCACTTCGCTATCATTTTCCTGAACGCAATCGTATCATTGCGGGAC
TTTCACATGGTGTAGTAGTGATAGAAGCAAAGTTACGAAGTGGTAGTTTAATTACTTGTGAGCGCGCTCTGGAAGAAGGA
AGAGATATTTTCGCTGTACCAGGAAACATAGCAGATGGATTTTCAGATGGCTGTAATCATCTAATTCAACAAGGAGCAAA
ATTAATCTACCAAGCCCAAGATATCTTAGAAGAATATTTGTATGATTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (76-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	86.525	100	0.865
dprA	Streptococcus mutans UA159	60.072	98.582	0.592
dprA/cilB/dalA	Streptococcus mitis SK321	54.643	99.291	0.543
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.929	99.291	0.535
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.929	99.291	0.535
dprA	Legionella pneumophila strain ERS1305867	38.768	97.872	0.379
dprA	Haemophilus influenzae Rd KW20	38.519	95.745	0.369
dprA	Bacillus subtilis subsp. subtilis str. 168	44.206	82.624	0.365
dprA	Latilactobacillus sakei subsp. sakei 23K	40	90.426	0.362