Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HUT07_RS03725 Genome accession   NZ_CP054931
Coordinates   842753..844012 (-) Length   419 a.a.
NCBI ID   WP_176019791.1    Uniprot ID   A0A7H8NMH3
Organism   Stenotrophomonas sp. NA06056     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 837753..849012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUT07_RS03695 (HUT07_03695) - 837791..838264 (+) 474 WP_176019786.1 hypothetical protein -
  HUT07_RS03700 (HUT07_03700) - 838273..838950 (+) 678 WP_025874286.1 response regulator transcription factor -
  HUT07_RS03705 (HUT07_03705) - 838913..840283 (+) 1371 WP_176019787.1 HAMP domain-containing sensor histidine kinase -
  HUT07_RS03710 (HUT07_03710) - 840820..841206 (+) 387 WP_176019788.1 hypothetical protein -
  HUT07_RS03715 (HUT07_03715) coaE 841259..841870 (-) 612 WP_176019789.1 dephospho-CoA kinase -
  HUT07_RS03720 (HUT07_03720) - 841882..842745 (-) 864 WP_176019790.1 A24 family peptidase -
  HUT07_RS03725 (HUT07_03725) pilC 842753..844012 (-) 1260 WP_176019791.1 type II secretion system F family protein Machinery gene
  HUT07_RS03730 (HUT07_03730) - 844360..844746 (+) 387 WP_176019792.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  HUT07_RS03735 (HUT07_03735) pilB 844879..846606 (+) 1728 WP_176019793.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HUT07_RS03740 (HUT07_03740) pilR 846736..848109 (-) 1374 WP_176019794.1 sigma-54 dependent transcriptional regulator Regulator

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45865.17 Da        Isoelectric Point: 10.0439

>NTDB_id=455387 HUT07_RS03725 WP_176019791.1 842753..844012(-) (pilC) [Stenotrophomonas sp. NA06056]
MSVSRSAIKKEPVARATMELQPFVWQGTDKRGVKMKGEQLAKNANLLRAELRRQGINPDQVKPKPKPLFGAAGKAIGTKD
ISFFSRQMATMMKSGVPIVSALEIIGSGHKNPRMKKMVDGVRTDIEGGSSLYESVSKYPVQFDELYRNLVRAGEGAGVLE
TVLDTVATYKENIEALKGKIKKALFYPAMVIAVALLVSAILLIYVVPQFEDVFKSFGADLPAFTQIIVNASRFMVSWWWL
IAIIVIGSIVGFVMAYKRSPPMQHAMDRFILKVPVIGQIMHNSAIARFSRTTAVTFKAGVPLVEALGIVAGATGNKVYEE
AVLRMRDDVSVGYPVNMAMKQTNLFPHMVVQMTSIGEEAGALDTMLFKVAEYYEQEVNNAVDALSSLLEPMIMVFIGVVV
GGMVVGMYLPIFKLASVVG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=455387 HUT07_RS03725 WP_176019791.1 842753..844012(-) (pilC) [Stenotrophomonas sp. NA06056]
ATGTCTGTCAGTCGCAGTGCGATCAAGAAAGAACCGGTGGCCCGCGCCACCATGGAGTTGCAGCCGTTTGTCTGGCAGGG
GACCGACAAGCGGGGCGTGAAGATGAAAGGCGAGCAGCTGGCGAAGAACGCCAACCTGCTGCGCGCTGAGCTGCGCCGGC
AGGGGATCAACCCCGACCAGGTCAAGCCCAAGCCGAAGCCACTGTTCGGTGCCGCCGGCAAGGCAATCGGCACCAAGGAC
ATCTCCTTCTTCAGCCGGCAGATGGCCACGATGATGAAGTCCGGCGTGCCGATCGTGTCGGCGCTGGAGATCATCGGCAG
CGGACACAAAAACCCGCGCATGAAGAAGATGGTCGACGGGGTCCGCACCGACATCGAGGGCGGCTCGTCGCTGTACGAGT
CGGTCAGCAAGTACCCGGTGCAGTTCGACGAGCTGTACCGCAACCTGGTGCGCGCCGGTGAAGGCGCCGGTGTGCTGGAA
ACGGTGCTGGATACCGTAGCCACCTACAAGGAAAACATCGAAGCGCTGAAGGGCAAGATCAAGAAGGCCCTGTTCTACCC
GGCGATGGTGATCGCGGTGGCGCTGCTGGTCAGCGCCATCCTTCTTATCTACGTGGTACCGCAGTTCGAGGACGTGTTCA
AAAGCTTCGGCGCCGATCTGCCCGCTTTCACACAGATCATCGTCAACGCTTCGCGCTTCATGGTGTCCTGGTGGTGGCTG
ATCGCCATCATCGTGATCGGCAGCATCGTCGGCTTCGTCATGGCCTACAAGCGTTCGCCCCCGATGCAGCATGCGATGGA
CCGCTTCATCCTGAAGGTGCCGGTGATCGGCCAGATCATGCACAACAGTGCCATCGCCCGCTTCTCGCGCACCACGGCGG
TGACCTTCAAGGCCGGCGTGCCGCTGGTGGAGGCACTGGGCATCGTCGCCGGCGCCACCGGCAACAAGGTCTATGAGGAG
GCCGTGCTGCGCATGCGCGACGACGTGTCGGTCGGCTATCCAGTCAACATGGCGATGAAGCAGACCAACCTGTTCCCGCA
TATGGTGGTACAGATGACATCCATCGGCGAAGAGGCCGGTGCGCTGGATACCATGCTGTTCAAGGTGGCCGAGTATTATG
AGCAGGAGGTCAACAATGCCGTTGACGCCTTGAGCAGCCTGCTCGAACCGATGATCATGGTGTTCATCGGTGTGGTCGTG
GGCGGCATGGTCGTCGGCATGTACCTGCCGATCTTCAAGCTCGCCTCCGTCGTCGGATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(84-207)

Type II secretion system (T2SS), protein F (T2SSF)

(288-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8NMH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

53.383

95.227

0.508
  pilC Pseudomonas stutzeri DSM 10701

52.778

94.511

0.499
  pilC Acinetobacter baumannii D1279779

50.123

97.136

0.487
  pilC Acinetobacter baylyi ADP1

49.754

96.897

0.482
  pilG Neisseria gonorrhoeae MS11

43.577

94.749

0.413
  pilG Neisseria meningitidis 44/76-A

43.073

94.749

0.408
  pilC Vibrio cholerae strain A1552

41.133

96.897

0.399
  pilC Vibrio campbellii strain DS40M4

40.898

95.704

0.391