Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HRE60_RS00335 Genome accession   NZ_CP054153
Coordinates   56977..58242 (+) Length   421 a.a.
NCBI ID   WP_181670842.1    Uniprot ID   A0A7L6WIR8
Organism   Streptococcus salivarius strain DB-B5     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 51977..63242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS00305 (HRE60_00305) - 52309..52746 (-) 438 WP_118189691.1 LytTR family DNA-binding domain-containing protein -
  HRE60_RS00310 (HRE60_00310) - 52925..53230 (+) 306 WP_048674007.1 hypothetical protein -
  HRE60_RS00315 (HRE60_00315) mutL 53280..55217 (+) 1938 WP_181670841.1 DNA mismatch repair endonuclease MutL -
  HRE60_RS00320 (HRE60_00320) - 55348..55569 (+) 222 WP_002886321.1 hypothetical protein -
  HRE60_RS00325 (HRE60_00325) ruvA 55727..56317 (+) 591 WP_004181981.1 Holliday junction branch migration protein RuvA -
  HRE60_RS00330 (HRE60_00330) - 56326..56880 (+) 555 WP_004181971.1 DNA-3-methyladenine glycosylase I -
  HRE60_RS00335 (HRE60_00335) cinA 56977..58242 (+) 1266 WP_181670842.1 competence/damage-inducible protein A Machinery gene
  HRE60_RS00340 (HRE60_00340) recA 58283..59422 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  HRE60_RS00345 (HRE60_00345) spx 59592..59990 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45496.64 Da        Isoelectric Point: 5.4833

>NTDB_id=451139 HRE60_RS00335 WP_181670842.1 56977..58242(+) (cinA) [Streptococcus salivarius strain DB-B5]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNESRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGIITAQGVTYVVLPGPPSELKPM
VNQELIPALTENHSSLYSRVLRFFGVGESQLVTVLKDFIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKHHGKTITAAESLTAGLFQATIADFSGASQVFKGGFVTYSIEEKAKM
LGIPLSQLEEHGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQETT

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=451139 HRE60_RS00335 WP_181670842.1 56977..58242(+) (cinA) [Streptococcus salivarius strain DB-B5]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACCGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAGCCGCCTACTTTCAGTTCTTG
ATCAAGCCAGTCAGCGTAGTGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACCTAACCAAGCAAACA
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAGCACACACGAACGCCTAATAATGAACGTCAAGCACAAATTGTTGAGGGAGCTATTCCCTTGCAAAACCCGACAGGTC
TTGCAGTTGGAGGGATTATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAAGAACTTATTCCAGCTCTTACTGAGAATCACTCAAGTCTTTATTCGAGAGTCCTAAGATTCTTTGGCGTTGG
AGAAAGTCAATTAGTGACTGTTCTGAAGGATTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATATGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCAACAAAGGCTTCTTCGCAAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAGAAACAA
ATTCGTTCGACTAAAACTCTAGATGGAAAATCCTTATCTGATTTCATTTATGGATATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGCACCATGGCAAGACCATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
CTATTGCTGATTTTTCAGGAGCCTCACAAGTATTTAAAGGTGGCTTTGTTACTTACAGCATTGAAGAAAAAGCTAAAATG
TTGGGTATTCCTTTGTCGCAACTAGAAGAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCTCG
AGCTAAAACAGATAGCGATTATGGAATTGCACTTACCGGTGTAGCTGGACCAGATTCCTTAGAAGGACACCCAGCAGGTA
CGGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGATGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAGACAACTTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L6WIR8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.418

99.525

0.751
  cinA Streptococcus mitis NCTC 12261

74.463

99.525

0.741
  cinA Streptococcus pneumoniae TIGR4

73.986

99.525

0.736
  cinA Streptococcus pneumoniae Rx1

73.747

99.525

0.734
  cinA Streptococcus pneumoniae R6

73.747

99.525

0.734
  cinA Streptococcus pneumoniae D39

73.508

99.525

0.732
  cinA Streptococcus mutans UA159

72.182

99.05

0.715
  cinA Streptococcus suis isolate S10

55.288

98.812

0.546
  cinA Bacillus subtilis subsp. subtilis str. 168

45.368

100

0.454