Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   STCNRZ385_RS08990 Genome accession   NZ_CP065495
Coordinates   1730331..1731272 (-) Length   313 a.a.
NCBI ID   WP_180483385.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CNRZ385     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1725331..1736272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STCNRZ385_RS08950 (STCNRZ385_08930) - 1725407..1726600 (-) 1194 WP_084826168.1 acetate kinase -
  STCNRZ385_RS08955 (STCNRZ385_08935) comGH 1726656..1727612 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  STCNRZ385_RS08960 (STCNRZ385_08940) comGG 1727657..1727974 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  STCNRZ385_RS08965 (STCNRZ385_08945) comGF 1727952..1728389 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  STCNRZ385_RS08970 (STCNRZ385_08950) comGE 1728373..1728666 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  STCNRZ385_RS08975 (STCNRZ385_08955) comGD 1728638..1729066 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  STCNRZ385_RS08980 (STCNRZ385_08960) comGC 1729026..1729352 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  STCNRZ385_RS08985 (STCNRZ385_08965) comGB 1729349..1730449 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  STCNRZ385_RS08990 (STCNRZ385_08970) comGA/cglA/cilD 1730331..1731272 (-) 942 WP_180483385.1 competence type IV pilus ATPase ComGA Machinery gene
  STCNRZ385_RS08995 (STCNRZ385_08975) - 1731353..1731715 (-) 363 WP_014608746.1 DUF1033 family protein -
  STCNRZ385_RS09000 (STCNRZ385_08980) rpoC 1731874..1735512 (-) 3639 WP_011226631.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35552.76 Da        Isoelectric Point: 6.8365

>NTDB_id=449199 STCNRZ385_RS08990 WP_180483385.1 1730331..1731272(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain CNRZ385]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVARMMVGEKRRSQLGSCDYD
CGDGHLVSLRLSTVGDYRGLESLVIRILHSERRELVYWNQGIQPIKDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKRDNVLQLQVNQAIDMTYDSLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSIAGV
YERLLDLGVDKSELDNALQGISYMRLIKGGGVIDFARENFQNHSSTNWNQQLEGLVKQGCLTERDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=449199 STCNRZ385_RS08990 WP_180483385.1 1730331..1731272(-) (comGA/cglA/cilD) [Streptococcus thermophilus strain CNRZ385]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTATGAGCTCTATATGCGAGTCGGGCAAGAGAGGAGATTGATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGAGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTGGGTTCATGTGACTATGAT
TGTGGTGACGGTCACTTGGTTTCTCTGCGTTTATCAACTGTTGGAGACTATCGAGGTTTGGAGAGCTTGGTTATCCGTAT
CCTACATTCCGAACGTCGAGAATTAGTGTATTGGAATCAAGGAATCCAGCCTATTAAGGATGCCTTGGATTATAGAGGAC
TGTATCTCTTTGCGGGTCCCGTAGGTTCTGGGAAGACCACACTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGGCAG
CAGGTAATTTCGATTGAGGATCCTGTTGAAATCAAACGGGATAATGTCTTGCAACTCCAGGTTAATCAGGCGATTGATAT
GACCTATGATAGTTTGATTAAGCTATCTCTACGTCACCGTCCAGATGTTTTGATTATTGGGGAGATTCGGGATAAGGAGA
CTGCCCGGGCAGTTATTAGAGCTAGTCTAACAGGTGTAACTGTTCTTTCAACTATTCATGCTAAGAGTATTGCTGGCGTT
TACGAACGTCTCTTGGACCTTGGCGTAGATAAGTCTGAGTTGGATAATGCTCTACAAGGCATTTCCTACATGCGTTTGAT
CAAGGGAGGAGGTGTGATTGATTTTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAG
GTTTGGTTAAACAAGGATGTCTCACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(10-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

99.361

0.645
  comGA Streptococcus mutans UA159

64.217

100

0.642
  comGA Streptococcus mutans UA140

64.217

100

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.666

99.361

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.666

99.361

0.633
  comGA Streptococcus gordonii str. Challis substr. CH1

62.62

100

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.577

99.681

0.604
  comGA Lactococcus lactis subsp. cremoris KW2

50.804

99.361

0.505
  comGA Latilactobacillus sakei subsp. sakei 23K

38.158

97.125

0.371