Detailed information NTG0449198

Bioinformatically predicted

Overview

• Name: comGB
• Type: Machinery gene
• Locus tag: STCNRZ385_RS08985
• Genome accession: NZ_CP065495
• Coordinates: 1729349..1730449 (-)
• Length: 366 a.a.
• NCBI ID: WP_116920398.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ385
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1724349..1735449

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ385_RS08940	-	1724674..1724949 (-)	276	WP_084830830.1	CAAX protease	-
STCNRZ385_RS08945 (STCNRZ385_08925)	-	1724961..1725158 (-)	198	WP_084826167.1	helix-turn-helix transcriptional regulator	-
STCNRZ385_RS08950 (STCNRZ385_08930)	-	1725407..1726600 (-)	1194	WP_084826168.1	acetate kinase	-
STCNRZ385_RS08955 (STCNRZ385_08935)	comGH	1726656..1727612 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STCNRZ385_RS08960 (STCNRZ385_08940)	comGG	1727657..1727974 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
STCNRZ385_RS08965 (STCNRZ385_08945)	comGF	1727952..1728389 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
STCNRZ385_RS08970 (STCNRZ385_08950)	comGE	1728373..1728666 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
STCNRZ385_RS08975 (STCNRZ385_08955)	comGD	1728638..1729066 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STCNRZ385_RS08980 (STCNRZ385_08960)	comGC	1729026..1729352 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
STCNRZ385_RS08985 (STCNRZ385_08965)	comGB	1729349..1730449 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
STCNRZ385_RS08990 (STCNRZ385_08970)	comGA/cglA/cilD	1730331..1731272 (-)	942	WP_180483385.1	competence type IV pilus ATPase ComGA	Machinery gene
STCNRZ385_RS08995 (STCNRZ385_08975)	-	1731353..1731715 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41797.91 Da
• Isoelectric Point: 10.1084

>NTDB_id=449198 STCNRZ385_RS08985 WP_116920398.1 1729349..1730449(-) (comGB) [Streptococcus thermophilus strain CNRZ385]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=449198 STCNRZ385_RS08985 WP_116920398.1 1729349..1730449(-) (comGB) [Streptococcus thermophilus strain CNRZ385]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterProScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB	Streptococcus mutans UA140	54.678	93.443	0.511
comGB	Streptococcus mutans UA159	54.678	93.443	0.511
comGB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413