Detailed information NTG0447635

Bioinformatically predicted

Overview

• Name: comGD
• Type: Machinery gene
• Locus tag: ST90728_RS08950
• Genome accession: NZ_CP065479
• Coordinates: 1733049..1733477 (-)
• Length: 142 a.a.
• NCBI ID: WP_011226626.1
• Uniprot ID: Q5M2G1
• Organism: Streptococcus thermophilus strain 90728
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1728049..1738477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90728_RS08910 (ST90728_08890)	-	1728187..1728630 (-)	444	WP_002946118.1	hypothetical protein	-
ST90728_RS08915	-	1728704..1729129 (-)	426	WP_096811681.1	CPBP family intramembrane glutamic endopeptidase	-
ST90728_RS08920 (ST90728_08900)	-	1729372..1729569 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
ST90728_RS08925 (ST90728_08905)	-	1729818..1731011 (-)	1194	WP_347114096.1	acetate kinase	-
ST90728_RS08930 (ST90728_08910)	comGH	1731067..1732023 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST90728_RS08935 (ST90728_08915)	comGG	1732068..1732385 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	Machinery gene
ST90728_RS08940 (ST90728_08920)	comGF	1732363..1732800 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST90728_RS08945 (ST90728_08925)	comGE	1732784..1733077 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	Machinery gene
ST90728_RS08950 (ST90728_08930)	comGD	1733049..1733477 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST90728_RS08955 (ST90728_08935)	comGC	1733437..1733763 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST90728_RS08960 (ST90728_08940)	comGB	1733760..1734860 (-)	1101	WP_116920398.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST90728_RS08965 (ST90728_08945)	comGA/cglA/cilD	1734742..1735683 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
ST90728_RS08970 (ST90728_08950)	-	1735764..1736126 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 15859.45 Da
• Isoelectric Point: 10.3330

>NTDB_id=447635 ST90728_RS08950 WP_011226626.1 1733049..1733477(-) (comGD) [Streptococcus thermophilus strain 90728]
MRNMVVKAAQWPIRAFTLLESLMTLAVVVFLTLSLSGSVTGIFQQVEINLFYLRFEYLYRDSQRLASAEGSNVELQLTKD
KVSNGRSSLLIPKSIHLDKGQTLVFDAKGGNSSLTKIRFSSDKEVVTYLLNMGSGKYKKTIS

Nucleotide

• Length: 429 bp

>NTDB_id=447635 ST90728_RS08950 WP_011226626.1 1733049..1733477(-) (comGD) [Streptococcus thermophilus strain 90728]
ATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGCCAATTAGAGCTTTCACATTGTTGGAGAGCCTGATGACACTAGCAGT
GGTTGTCTTTCTCACTCTGAGTTTGTCAGGCTCAGTCACAGGTATTTTTCAGCAGGTCGAGATTAATCTTTTTTATCTGC
GTTTTGAGTACCTATATCGAGATAGTCAGCGCTTGGCATCAGCGGAAGGATCTAATGTTGAATTGCAGTTAACTAAGGAT
AAGGTTAGTAATGGAAGGTCTAGTCTGCTTATTCCTAAAAGTATTCATCTGGATAAGGGGCAGACGCTAGTGTTTGATGC
TAAAGGAGGCAACTCTAGCCTCACGAAAATTCGTTTTTCAAGTGATAAGGAGGTGGTGACCTATCTGCTTAACATGGGCA
GTGGTAAATATAAAAAGACGATCTCTTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: Q5M2G1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGD	Streptococcus mutans UA140	52.672	92.254	0.486
comGD	Streptococcus mutans UA159	52.672	92.254	0.486
comGD	Streptococcus gordonii str. Challis substr. CH1	41.429	98.592	0.408
comGD/cglD	Streptococcus pneumoniae Rx1	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae D39	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae R6	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis NCTC 12261	44.094	89.437	0.394
comGD/cglD	Streptococcus pneumoniae TIGR4	44.094	89.437	0.394
comGD/cglD	Streptococcus mitis SK321	43.307	89.437	0.387
comGD	Lactococcus lactis subsp. cremoris KW2	40.909	92.958	0.38