Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HPY13_RS02325 Genome accession   NZ_CP053796
Coordinates   482859..484085 (-) Length   408 a.a.
NCBI ID   WP_000648506.1    Uniprot ID   A0A0E3W4T9
Organism   Vibrio cholerae strain SL4G     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 477859..489085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPY13_RS02300 (HPY13_02300) parC 477860..480145 (+) 2286 WP_046121363.1 DNA topoisomerase IV subunit A -
  HPY13_RS02305 (HPY13_02305) yacG 480194..480391 (-) 198 WP_000162865.1 DNA gyrase inhibitor YacG -
  HPY13_RS02310 (HPY13_02310) zapD 480549..481289 (-) 741 WP_000207193.1 cell division protein ZapD -
  HPY13_RS02315 (HPY13_02315) coaE 481321..481929 (-) 609 WP_069216898.1 dephospho-CoA kinase -
  HPY13_RS02320 (HPY13_02320) pilD 481926..482801 (-) 876 WP_033932898.1 A24 family peptidase Machinery gene
  HPY13_RS02325 (HPY13_02325) pilC 482859..484085 (-) 1227 WP_000648506.1 type II secretion system F family protein Machinery gene
  HPY13_RS02330 (HPY13_02330) pilB 484128..485816 (-) 1689 WP_108243691.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HPY13_RS02335 (HPY13_02335) pilA 485820..486248 (-) 429 WP_094393042.1 pilin Machinery gene
  HPY13_RS02340 (HPY13_02340) nadC 486493..487383 (-) 891 WP_094393041.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HPY13_RS02345 (HPY13_02345) ampD 487685..488230 (+) 546 WP_094393039.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HPY13_RS02350 (HPY13_02350) fldB 488379..488897 (-) 519 WP_069503252.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45090.38 Da        Isoelectric Point: 10.3424

>NTDB_id=447362 HPY13_RS02325 WP_000648506.1 482859..484085(-) (pilC) [Vibrio cholerae strain SL4G]
MKATQTLPLKNYRWKGINSNGKKVSGQMLAISEIEVRDKLKDQHIQIKKLKKGSVSLLARLTHRVKGKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKSVEAGTPLSKAMRTASAHFDTLYVDLVETGEMSGNLPEVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQVLKLSHWVQAYSLWAFIAIAAAIFG
LKALRKNSFQIRLKTSRLGLKFPIIGNVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTSGNVHFETAINEVYRDTAA
GMPMYIAMRNTDAFPEMVLQMVMIGEESGQLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=447362 HPY13_RS02325 WP_000648506.1 482859..484085(-) (pilC) [Vibrio cholerae strain SL4G]
ATGAAAGCGACCCAAACCTTACCTCTGAAAAATTATCGCTGGAAAGGCATCAACAGCAACGGCAAAAAAGTTTCCGGTCA
GATGCTCGCCATCTCCGAAATCGAGGTGCGCGATAAGCTCAAAGATCAGCATATTCAGATCAAAAAACTCAAAAAAGGCA
GTGTCTCTTTATTGGCGCGCCTAACTCATCGCGTGAAAGGCAAAGACATCACGATTTTGACTCGGCAGTTGGCGACCATG
CTCACCACGGGCGTACCCATTGTGCAAGCCCTCAAGTTGGTGGGCGATAATCACCGTAAAGCTGAGATGAAATCGATTCT
GGCGCAAATTACCAAAAGCGTGGAAGCGGGCACGCCGCTTTCCAAGGCGATGCGCACCGCCAGCGCCCATTTTGATACCT
TGTATGTCGACTTAGTGGAAACCGGAGAGATGTCCGGTAACTTACCTGAAGTGTTTGAGCGTTTGGCCACCTACCGCGAG
AAAAGCGAGCAACTACGCGCCAAGGTGATTAAAGCGCTCATCTACCCCAGCATGGTTGTGTTGGTCGCACTCGGGGTATC
TTACTTAATGCTCACCATGGTCATCCCAGAGTTTGAAAGCATGTTTAAAGGCTTTGGTGCTGAACTGCCTTGGTTTACGC
AGCAAGTGCTGAAACTCTCACACTGGGTACAGGCTTACAGTTTATGGGCATTTATCGCCATCGCAGCAGCCATTTTTGGC
TTGAAAGCGCTGCGTAAAAACTCTTTCCAGATCCGTTTAAAAACCAGCCGCTTAGGGCTGAAATTTCCGATTATTGGCAA
TGTGCTCGCCAAAGCGTCCATCGCCAAATTCAGCCGCACGCTTGCCACCAGCTTTGCCGCGGGGATTCCGATCCTCGCCA
GTTTAAAAACCACCGCCAAAACCTCCGGCAATGTGCACTTTGAAACCGCGATTAATGAGGTGTACCGCGATACCGCTGCG
GGTATGCCGATGTACATTGCCATGCGCAATACCGACGCTTTTCCGGAAATGGTGCTGCAAATGGTGATGATCGGTGAAGA
GTCAGGGCAATTAGATGACATGCTCAACAAGGTCGCGACCATCTATGAATTTGAAGTCGATAACACAGTCGATAACTTGG
GCAAGATTCTTGAACCACTGATCATCGTGTTTCTTGGGACGGTCGTGGGCGGCTTAGTGGTGGCGATGTACTTACCTATC
TTTAACTTAATGAGTGTATTGGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E3W4T9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

99.51

100

0.995
  pilC Vibrio campbellii strain DS40M4

74

98.039

0.725
  pilC Acinetobacter baumannii D1279779

42.647

100

0.426
  pilC Acinetobacter baylyi ADP1

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.211

97.549

0.412
  pilC Pseudomonas stutzeri DSM 10701

42.172

97.059

0.409
  pilG Neisseria gonorrhoeae MS11

41.045

98.529

0.404
  pilG Neisseria meningitidis 44/76-A

40.547

98.529

0.4