Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GE023_RS10230 Genome accession   NZ_CP053789
Coordinates   2082695..2083966 (-) Length   423 a.a.
NCBI ID   WP_159305738.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2077695..2088966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS11095 - 2079342..2079467 (-) 126 WP_257865518.1 hypothetical protein -
  GE023_RS10205 (GE023_010200) - 2079545..2079850 (-) 306 WP_003045716.1 DUF1292 domain-containing protein -
  GE023_RS10210 (GE023_010205) ruvX 2079861..2080280 (-) 420 WP_039994721.1 Holliday junction resolvase RuvX -
  GE023_RS10215 (GE023_010210) - 2080277..2080546 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  GE023_RS10220 (GE023_010215) spx 2080658..2081056 (-) 399 WP_093999148.1 transcriptional regulator Spx -
  GE023_RS10225 (GE023_010220) recA 2081454..2082590 (-) 1137 WP_093999149.1 recombinase RecA Machinery gene
  GE023_RS10230 (GE023_010225) cinA 2082695..2083966 (-) 1272 WP_159305738.1 competence/damage-inducible protein A Machinery gene
  GE023_RS11100 - 2084083..2084241 (-) 159 WP_223824822.1 VOC family protein -
  GE023_RS10240 (GE023_010235) - 2084439..2085011 (-) 573 WP_159305737.1 DNA-3-methyladenine glycosylase I -
  GE023_RS10245 (GE023_010240) ruvA 2085021..2085617 (-) 597 WP_003045733.1 Holliday junction branch migration protein RuvA -
  GE023_RS10250 (GE023_010245) - 2085601..2086839 (-) 1239 WP_003045734.1 MFS transporter -
  GE023_RS10255 (GE023_010250) mutL 2086850..2088832 (-) 1983 WP_164406143.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45928.64 Da        Isoelectric Point: 5.5619

>NTDB_id=447186 GE023_RS10230 WP_159305738.1 2082695..2083966(-) (cinA) [Streptococcus canis strain HL_98_2]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIAIASQRSDLVILCGGLGPTEDDLTKQT
LAKFLKKDLVFDAQASQKLDDFFASRKQSSRTPNNERQAQLIAGSRPLQNKTGLAVGGLITVDDVTYVVLPGPPSELKPM
VNQELVPFLAHQSSKLYSKVLRFFGIGESQLVTILSDFIENQTDPTIAPYAKTGEVTLRLSTKAKDQTLADKKLAQLEAQ
LLSRKTPDNQPLSDFLYGYGEDNSLARETFELLIKNDKTITAAESLTAGLFQSTLANFSGASQVFNGGFVTYSMEEKAKM
LDIPLEDLKSYGVVSAYTAEKMAGQARLLTGADIGVSLTGVAGPDMLENQPVGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPKNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=447186 GE023_RS10230 WP_159305738.1 2082695..2083966(-) (cinA) [Streptococcus canis strain HL_98_2]
ATGAAAGCTGAACTGATTGCAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCCCAATTTTTGTCGGA
GAAAATGGCAGAGCTAGGCATTGATGTCTATTTCCAGACAGCAGTTGGTGATAATGAAGAGCGTCTACTTTCTGTGATTG
CTATTGCTAGTCAACGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGACCTACCGAAGATGATTTAACCAAGCAAACC
CTAGCAAAATTTTTGAAGAAAGATTTGGTTTTTGATGCTCAAGCGAGTCAAAAACTAGATGACTTTTTTGCCAGTCGTAA
GCAGTCATCTCGAACACCAAATAATGAGAGGCAGGCACAACTAATTGCCGGATCAAGACCTTTACAAAATAAGACAGGGC
TGGCAGTTGGTGGTTTGATTACGGTTGATGATGTGACTTACGTTGTTTTACCGGGTCCTCCTAGTGAACTAAAGCCTATG
GTTAATCAGGAATTAGTACCTTTTCTGGCGCATCAGTCTAGCAAACTTTATTCGAAGGTTTTACGCTTTTTTGGGATTGG
CGAGAGTCAATTAGTAACGATTTTATCAGATTTTATTGAAAATCAGACTGATCCCACTATTGCTCCTTATGCTAAGACAG
GGGAGGTCACTCTTCGCTTATCAACAAAAGCTAAGGACCAGACTTTAGCAGATAAGAAACTAGCCCAGTTAGAAGCTCAG
CTATTATCCCGAAAAACTCCTGACAATCAGCCGTTATCAGATTTTCTTTATGGCTATGGAGAGGATAATTCCTTGGCGCG
TGAGACATTTGAGCTCTTAATAAAAAATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAATTTTTCAGGAGCTTCCCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCCAAAATG
CTAGATATTCCTTTAGAAGATTTGAAATCATATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGGACAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTGAGTTTAACAGGTGTTGCTGGGCCAGATATGTTGGAGAACCAGCCTGTAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATTGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTAAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-171)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.34

100

0.723
  cinA Streptococcus mitis SK321

71.942

98.582

0.709
  cinA Streptococcus mitis NCTC 12261

71.463

98.582

0.704
  cinA Streptococcus pneumoniae TIGR4

70.743

98.582

0.697
  cinA Streptococcus pneumoniae Rx1

70.743

98.582

0.697
  cinA Streptococcus pneumoniae R6

70.743

98.582

0.697
  cinA Streptococcus pneumoniae D39

70.504

98.582

0.695
  cinA Streptococcus suis isolate S10

53.125

98.345

0.522
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456