Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   GE023_RS00835 Genome accession   NZ_CP053789
Coordinates   134961..135287 (+) Length   108 a.a.
NCBI ID   WP_159305269.1    Uniprot ID   A0AAE4TS52
Organism   Streptococcus canis strain HL_98_2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 129961..140287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS00820 (GE023_000820) - 132598..132963 (+) 366 WP_125073632.1 DUF1033 family protein -
  GE023_RS00825 (GE023_000825) comYA 133050..133991 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE023_RS00830 (GE023_000830) comYB 133924..134958 (+) 1035 WP_223824829.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE023_RS00835 (GE023_000835) comYC 134961..135287 (+) 327 WP_159305269.1 competence type IV pilus major pilin ComGC Machinery gene
  GE023_RS00840 (GE023_000840) comGD 135262..135690 (+) 429 WP_236494085.1 competence type IV pilus minor pilin ComGD -
  GE023_RS00845 (GE023_000845) comGE 135668..135943 (+) 276 WP_003046190.1 competence type IV pilus minor pilin ComGE -
  GE023_RS00850 (GE023_000850) comGF 135924..136364 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF -
  GE023_RS00855 (GE023_000855) comGG 136342..136722 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE023_RS00860 (GE023_000860) comYH 136772..137725 (+) 954 WP_003046195.1 class I SAM-dependent methyltransferase Machinery gene
  GE023_RS00865 (GE023_000865) - 137784..138980 (+) 1197 WP_093998734.1 acetate kinase -
  GE023_RS00870 (GE023_000870) - 139300..139506 (+) 207 WP_003046200.1 helix-turn-helix transcriptional regulator -
  GE023_RS00875 (GE023_000875) - 139507..139647 (+) 141 Protein_126 CPBP family glutamic-type intramembrane protease -
  GE023_RS10810 - 139772..139927 (+) 156 WP_236493542.1 hypothetical protein -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12428.40 Da        Isoelectric Point: 9.6762

>NTDB_id=447140 GE023_RS00835 WP_159305269.1 134961..135287(+) (comYC) [Streptococcus canis strain HL_98_2]
MTNQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGHTAVVKLVENQAELYELSQGSKPSLSQLKE
DGSITDKQEKAYRDYYGKHKDEAQKLQP

Nucleotide


Download         Length: 327 bp        

>NTDB_id=447140 GE023_RS00835 WP_159305269.1 134961..135287(+) (comYC) [Streptococcus canis strain HL_98_2]
ATGACAAACCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCAAATTTAAGCAAGCAAAAAGACAGGGTTACCGAGACAGGTCATACCGCTG
TTGTTAAATTAGTGGAGAATCAAGCGGAGCTATATGAATTATCTCAGGGTTCAAAACCAAGTTTGAGCCAACTGAAGGAA
GATGGTAGCATCACTGACAAACAAGAAAAAGCTTATCGCGACTATTATGGCAAACATAAAGATGAAGCTCAAAAATTGCA
ACCTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

55.34

95.37

0.528

  comGC Lactococcus lactis subsp. cremoris KW2

57.292

88.889

0.509

  comGC/cglC Streptococcus mitis SK321

58.696

85.185

0.5

  comGC/cglC Streptococcus mitis NCTC 12261

57.609

85.185

0.491

  comGC/cglC Streptococcus pneumoniae TIGR4

56.522

85.185

0.481

  comGC/cglC Streptococcus pneumoniae Rx1

56.522

85.185

0.481

  comGC/cglC Streptococcus pneumoniae R6

56.522

85.185

0.481

  comGC/cglC Streptococcus pneumoniae D39

56.522

85.185

0.481

  comYC Streptococcus mutans UA159

58.621

80.556

0.472

  comYC Streptococcus mutans UA140

58.621

80.556

0.472

  comYC Streptococcus suis isolate S10

55.556

75

0.417