Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HPT10_RS24645 Genome accession   NZ_CP053705
Coordinates   5317014..5318231 (+) Length   405 a.a.
NCBI ID   WP_023126571.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain PAC6     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 5312014..5323231
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPT10_RS24625 (HPT10_24650) nadC 5313604..5314452 (+) 849 WP_023126570.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HPT10_RS24635 (HPT10_24660) - 5314606..5315079 (-) 474 WP_015503553.1 pilin -
  HPT10_RS24640 (HPT10_24665) pilB 5315310..5317010 (+) 1701 WP_073647569.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HPT10_RS24645 (HPT10_24670) pilC 5317014..5318231 (+) 1218 WP_023126571.1 type II secretion system F family protein Machinery gene
  HPT10_RS24650 (HPT10_24675) pilD 5318234..5319106 (+) 873 WP_003116251.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  HPT10_RS24655 (HPT10_24680) coaE 5319103..5319714 (+) 612 WP_003094654.1 dephospho-CoA kinase -
  HPT10_RS24660 (HPT10_24685) yacG 5319711..5319911 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  HPT10_RS24665 (HPT10_24690) - 5319948..5320157 (-) 210 WP_003094660.1 hypothetical protein -
  HPT10_RS24670 (HPT10_24695) - 5320263..5320952 (-) 690 WP_003103868.1 energy-coupling factor ABC transporter permease -
  HPT10_RS24675 (HPT10_24700) - 5320949..5321419 (-) 471 WP_023096122.1 hypothetical protein -
  HPT10_RS24680 (HPT10_24705) - 5321416..5321841 (-) 426 WP_003103865.1 GNAT family N-acetyltransferase -
  HPT10_RS24685 (HPT10_24710) - 5321974..5322603 (+) 630 WP_003094668.1 DUF1780 domain-containing protein -
  HPT10_RS24690 (HPT10_24715) - 5322600..5323049 (+) 450 WP_003094670.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44242.19 Da        Isoelectric Point: 9.8988

>NTDB_id=446478 HPT10_RS24645 WP_023126571.1 5317014..5318231(+) (pilC) [Pseudomonas aeruginosa strain PAC6]
MADKALKTCVFVWEGTDKKGAKVKGELAGQNTMLVKAQLRKQGINPLKVRKKGITLLGKGKRVKPMDIALFTRQMATMMG
AGVPLLQSFDIISEGFDNPNMRKLVDEIKQEVSAGNSLANSLRKKPIYFDDLYCNLVDAGEQSGALETLLDRVATYKEKT
ESLKAKIKKAMTYPIAVVLVAIIVSAILLIKVVPQFQSVFSSFGAELPAFTMMVINLSNLLQEWWLVVLIGLFSASFAIK
ESHKRSVNFRNTVDRYMLKIPIIGGILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRNAVSKIKQDVSTGM
QLNFSMRTTNVFPNMAIQMTAIGEESGSLDDMLGKVAAFYEEEVDNAVDNLTTLMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGSVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=446478 HPT10_RS24645 WP_023126571.1 5317014..5318231(+) (pilC) [Pseudomonas aeruginosa strain PAC6]
ATGGCGGATAAAGCGTTAAAAACCTGTGTTTTCGTCTGGGAAGGCACGGACAAGAAAGGGGCAAAGGTCAAGGGGGAGTT
GGCTGGCCAGAACACTATGCTGGTGAAGGCGCAACTGCGCAAACAGGGCATAAATCCGCTCAAGGTCAGAAAAAAGGGCA
TTACCCTTCTCGGCAAGGGAAAGCGCGTAAAGCCGATGGACATCGCACTATTTACTCGTCAGATGGCAACCATGATGGGT
GCTGGGGTTCCTCTCTTGCAATCGTTCGACATAATTTCCGAAGGTTTCGACAATCCCAACATGCGTAAACTGGTCGACGA
GATCAAACAAGAGGTCTCGGCGGGTAACAGCTTGGCAAACTCCTTGCGAAAGAAACCTATTTATTTTGACGATCTCTATT
GCAACCTAGTGGATGCAGGTGAACAATCTGGCGCCTTGGAGACTTTGCTTGACCGTGTTGCCACCTATAAGGAAAAAACC
GAATCGCTAAAAGCCAAGATAAAAAAGGCTATGACATACCCCATTGCCGTCGTCTTGGTCGCGATCATTGTTTCAGCCAT
TCTCCTGATCAAGGTCGTACCCCAGTTCCAATCCGTTTTCTCCAGTTTCGGAGCGGAACTACCAGCCTTTACAATGATGG
TGATAAACCTGTCAAATCTTTTACAGGAATGGTGGCTAGTCGTCCTCATAGGATTATTCAGCGCCAGCTTCGCCATCAAG
GAATCGCATAAGCGTTCAGTAAATTTCCGTAACACGGTAGACCGCTATATGTTGAAAATACCGATAATCGGAGGAATACT
TTACAAATCAGCCGTGGCACGTTACGCCCGTACACTTTCAACAACTTTCGCCGCAGGTGTTCCATTGGTGGAGGCACTAG
ACTCTGTCTCTGGAGCGACAGGAAACGTGGTATTCCGCAACGCGGTAAGCAAGATCAAACAGGATGTATCCACAGGTATG
CAATTGAACTTCTCCATGAGAACGACCAATGTATTCCCCAACATGGCAATCCAGATGACAGCCATCGGTGAGGAATCCGG
TTCTCTGGACGACATGTTGGGCAAGGTGGCTGCGTTCTATGAGGAGGAAGTAGACAATGCCGTCGACAATCTGACAACTC
TCATGGAACCTATGATCATGGCCGTGCTCGGCGTACTGGTCGGCGGCCTGATCATCGCTATGTATCTACCGATCTTCCAA
CTGGGTTCCGTTGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baumannii D1279779

58.911

99.753

0.588
  pilC Acinetobacter baylyi ADP1

59.045

98.272

0.58
  pilC Legionella pneumophila strain ERS1305867

54.04

97.778

0.528
  pilG Neisseria meningitidis 44/76-A

44.03

99.259

0.437
  pilG Neisseria gonorrhoeae MS11

43.781

99.259

0.435
  pilC Vibrio cholerae strain A1552

43.21

100

0.432
  pilC Vibrio campbellii strain DS40M4

43.182

97.778

0.422
  pilC Thermus thermophilus HB27

37.656

99.012

0.373