Detailed information NTG0443367

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: HLK68_RS07915
• Genome accession: NZ_CP053187
• Coordinates: 1633928..1634677 (+)
• Length: 249 a.a.
• NCBI ID: WP_132943034.1
• Uniprot ID: -
• Organism: Turicibacter sanguinis strain MOL361
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1628928..1639677

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLK68_RS07885 (HLK68_07900)	-	1629370..1629549 (-)	180	WP_132943028.1	hypothetical protein	-
HLK68_RS07890 (HLK68_07905)	-	1629938..1630960 (+)	1023	WP_132943029.1	hypothetical protein	-
HLK68_RS07895 (HLK68_07910)	-	1631146..1631514 (+)	369	WP_262942116.1	JAB domain-containing protein	-
HLK68_RS07900 (HLK68_07915)	-	1631767..1632405 (+)	639	WP_170837672.1	accessory gene regulator B family protein	-
HLK68_RS07905 (HLK68_07920)	-	1632374..1632547 (+)	174	WP_132943032.1	cyclic lactone autoinducer peptide	-
HLK68_RS07910 (HLK68_07925)	-	1632618..1633928 (+)	1311	WP_132943033.1	GHKL domain-containing protein	-
HLK68_RS07915 (HLK68_07930)	comE/blpR	1633928..1634677 (+)	750	WP_132943034.1	response regulator transcription factor	Regulator
HLK68_RS07920 (HLK68_07935)	-	1634875..1635507 (+)	633	WP_132943035.1	hypothetical protein	-
HLK68_RS07925 (HLK68_07940)	-	1635781..1636215 (+)	435	WP_132943036.1	JAB domain-containing protein	-
HLK68_RS07930 (HLK68_07945)	-	1636806..1637972 (-)	1167	WP_055305877.1	hypothetical protein	-
HLK68_RS07935 (HLK68_07950)	-	1637983..1638762 (-)	780	WP_055305878.1	YiiX/YebB-like N1pC/P60 family cysteine hydrolase	-

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29321.07 Da
• Isoelectric Point: 8.5910

>NTDB_id=443367 HLK68_RS07915 WP_132943034.1 1633928..1634677(+) (comE/blpR) [Turicibacter sanguinis strain MOL361]
MEIFILEDDPIQRYRLEKIIKEALEKSSILYKKIFATARPVQLLNEINSIGNHHIYFLDLEINNHLGKGLEIAQLIREKD
PYGTIVFVTTHSELAPKTFAYKVSALDFIEKDQSDFEFRKRIEECLIIANQYQQKPISEDSFIFENKYTKFQIPFSEILY
FETSEIPHKINLVTSKKNISFYGKLSDIVKMDGRLFSCHKSFVVNIPNIISVDKKNKLVYFNNGMFCFVSRRLLKEVENK
IEELRVKKF

Nucleotide

• Length: 750 bp

>NTDB_id=443367 HLK68_RS07915 WP_132943034.1 1633928..1634677(+) (comE/blpR) [Turicibacter sanguinis strain MOL361]
ATGGAGATTTTTATTTTAGAAGATGATCCAATTCAAAGATATAGATTAGAAAAAATTATTAAGGAAGCTTTAGAGAAGAG
TAGTATTTTATATAAGAAAATATTTGCTACGGCTAGACCAGTGCAACTTTTAAATGAGATTAATTCTATAGGAAATCATC
ATATCTACTTTTTAGATTTGGAAATTAATAATCATTTAGGAAAAGGATTAGAGATTGCTCAGCTTATACGTGAAAAAGAC
CCTTATGGAACAATTGTCTTTGTTACTACTCACTCAGAATTAGCTCCTAAGACATTTGCATATAAAGTTTCGGCTCTTGA
TTTTATTGAAAAAGATCAATCTGATTTTGAGTTTAGAAAAAGAATTGAAGAGTGTTTAATAATTGCTAATCAATACCAGC
AAAAACCAATAAGTGAAGATTCTTTTATATTCGAGAATAAATATACGAAATTTCAGATACCATTTTCAGAAATTTTGTAT
TTTGAAACATCTGAAATTCCACATAAAATTAACTTAGTAACATCTAAAAAAAATATTAGTTTTTATGGAAAGTTAAGTGA
TATTGTTAAGATGGATGGTCGTCTGTTTAGCTGCCATAAATCATTTGTAGTAAATATACCAAATATTATTAGTGTCGATA
AGAAGAATAAATTAGTCTATTTTAATAATGGTATGTTTTGTTTTGTTTCTCGAAGATTATTAAAAGAAGTTGAAAATAAG
ATAGAGGAATTAAGGGTTAAAAAATTCTAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-241)

• Response regulator receiver domain (Response_reg) (3-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.193	100	0.482
comE/comE1	Streptococcus equinus JB1	40.928	95.181	0.39
comE/comE2	Streptococcus equinus JB1	39.184	98.394	0.386
comE/comE2	Streptococcus gordonii strain NCTC7865	38.525	97.992	0.378
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.525	97.992	0.378
comE	Streptococcus pneumoniae Rx1	36.905	100	0.373
comE	Streptococcus pneumoniae D39	36.905	100	0.373
comE	Streptococcus pneumoniae R6	36.905	100	0.373
comE	Streptococcus pneumoniae TIGR4	36.905	100	0.373
comE	Streptococcus mitis SK321	36.759	100	0.373
comE	Streptococcus mitis NCTC 12261	36.364	100	0.369