Detailed information NTG0443367

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: IUJ36_RS00490
• Genome accession: NZ_CP064383
• Coordinates: 104724..105347 (+)
• Length: 207 a.a.
• NCBI ID: WP_000122253.1
• Uniprot ID: A0A370V1H3
• Organism: Escherichia coli O157:H7 strain PartA-EcoliO157H7-RM8376
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 99724..110347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ36_RS00470 (IUJ36_00470)	ampG	100118..101593 (-)	1476	WP_000098429.1	muropeptide MFS transporter AmpG	-
IUJ36_RS00475 (IUJ36_00475)	yajG	101637..102215 (-)	579	WP_000473502.1	lipoprotein	-
IUJ36_RS00480 (IUJ36_00480)	bolA	102520..102837 (+)	318	WP_000973448.1	transcriptional regulator BolA	-
IUJ36_RS00485 (IUJ36_00485)	tig	103181..104479 (+)	1299	WP_001198386.1	trigger factor	-
IUJ36_RS00490 (IUJ36_00490)	clpP	104724..105347 (+)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
IUJ36_RS00495 (IUJ36_00495)	clpX	105473..106747 (+)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
IUJ36_RS00500 (IUJ36_00500)	lon	106935..109289 (+)	2355	WP_001302567.1	endopeptidase La	-
IUJ36_RS00505 (IUJ36_00505)	hupB	109480..109770 (+)	291	WP_254892905.1	nucleoid-associated protein HU-beta	-

Sequence

Protein

• Length: 207 a.a.
• Molecular weight: 23186.65 Da
• Isoelectric Point: 5.6032

>NTDB_id=443367 IUJ36_RS00490 WP_000122253.1 104724..105347(+) (clpP) [Escherichia coli O157:H7 strain PartA-EcoliO157H7-RM8376]
MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSP
GGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN

Nucleotide

• Length: 624 bp

>NTDB_id=443367 IUJ36_RS00490 WP_000122253.1 104724..105347(+) (clpP) [Escherichia coli O157:H7 strain PartA-EcoliO157H7-RM8376]
ATGTCATACAGCGGCGAACGAGATAACTTTGCACCCCATATGGCGCTGGTGCCGATGGTCATTGAACAGACCTCACGTGG
TGAGCGCTCTTTTGATATCTATTCTCGTCTACTTAAGGAACGCGTCATTTTTCTGACTGGCCAGGTTGAAGACCATATGG
CTAACCTGATTGTGGCTCAGATGCTGTTCCTGGAAGCAGAAAACCCAGAAAAAGATATCTATCTGTACATTAACTCCCCA
GGCGGGGTGATCACTGCCGGGATGTCTATCTATGACACCATGCAGTTTATCAAGCCTGATGTCAGCACCATCTGTATGGG
CCAGGCGGCCTCGATGGGCGCTTTCTTGCTGACCGCAGGGGCAAAAGGTAAACGTTTTTGCCTGCCGAATTCGCGCGTGA
TGATTCACCAACCGTTGGGCGGCTACCAGGGCCAGGCGACCGATATCGAAATTCATGCCCGTGAAATTCTGAAAGTTAAA
GGGCGTATGAATGAACTTATGGCGCTTCATACGGGTCAATCATTAGAACAGATTGAACGTGATACCGAGCGCGATCGCTT
CCTTTCCGCCCCTGAAGCGGTGGAATACGGTCTGGTCGATTCGATTCTGACCCATCGTAATTGA

Domains

Predicted by InterProScan.

• Clp protease (CLP_protease) (26-205)

3D structure

• AlphaFold DB: A0A370V1H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	69.792	92.754	0.647
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	90.821	0.623
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	93.72	0.531
clpP	Streptococcus pneumoniae R6	55.155	93.72	0.517
clpP	Streptococcus pneumoniae TIGR4	55.155	93.72	0.517
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.155	93.72	0.517
clpP	Streptococcus pneumoniae Rx1	55.155	93.72	0.517
clpP	Streptococcus pneumoniae D39	55.155	93.72	0.517
clpP	Streptococcus thermophilus LMD-9	54.922	93.237	0.512
clpP	Streptococcus thermophilus LMG 18311	54.922	93.237	0.512
clpP	Streptococcus pyogenes JRS4	55.263	91.787	0.507
clpP	Streptococcus pyogenes MGAS315	55.263	91.787	0.507
clpP	Streptococcus mutans UA159	53.886	93.237	0.502