Detailed information NTG0443055

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HLB22_RS13665
• Genome accession: NZ_CP053101
• Coordinates: 2742646..2743533 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain EDCC5398
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2737646..2748533

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HLB22_RS13635 (HLB22_13645)	-	2737664..2737752 (+)	89	Protein_2657	hypothetical protein	-
HLB22_RS13640 (HLB22_13650)	-	2737860..2738357 (-)	498	WP_001065267.1	glutathione peroxidase	-
HLB22_RS13645 (HLB22_13655)	-	2738367..2738627 (-)	261	WP_072434822.1	hypothetical protein	-
HLB22_RS13650 (HLB22_13660)	-	2739009..2739122 (-)	114	WP_072384844.1	hypothetical protein	-
HLB22_RS13655 (HLB22_13665)	-	2739786..2741786 (-)	2001	WP_000776746.1	ABC transporter permease	-
HLB22_RS13660 (HLB22_13670)	-	2741783..2742538 (-)	756	WP_001670202.1	ABC transporter ATP-binding protein	-
HLB22_RS13665 (HLB22_13675)	braS	2742646..2743533 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HLB22_RS13670 (HLB22_13680)	braR	2743544..2744209 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HLB22_RS13675 (HLB22_13685)	-	2744235..2744435 (-)	201	WP_000604723.1	hypothetical protein	-
HLB22_RS13680 (HLB22_13690)	-	2744633..2746057 (+)	1425	WP_000953731.1	alkaline phosphatase	-
HLB22_RS13685 (HLB22_13695)	-	2746127..2746237 (+)	111	WP_001791296.1	hypothetical protein	-
HLB22_RS13690 (HLB22_13700)	-	2746340..2746795 (-)	456	WP_000106184.1	MarR family transcriptional regulator	-
HLB22_RS13695 (HLB22_13705)	-	2747041..2747802 (-)	762	WP_170267450.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=443055 HLB22_RS13665 WP_000143420.1 2742646..2743533(-) (braS) [Staphylococcus aureus strain EDCC5398]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=443055 HLB22_RS13665 WP_000143420.1 2742646..2743533(-) (braS) [Staphylococcus aureus strain EDCC5398]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993