Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HHM66_RS10370 Genome accession   NZ_CP053074
Coordinates   2097324..2098595 (-) Length   423 a.a.
NCBI ID   WP_015058134.1    Uniprot ID   A0AB33R8F3
Organism   Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2092324..2103595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HHM66_RS10340 (HHM66_10365) - 2092724..2093029 (-) 306 WP_003058733.1 DUF1292 domain-containing protein -
  HHM66_RS10345 (HHM66_10370) ruvX 2093040..2093459 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  HHM66_RS10350 (HHM66_10375) - 2093456..2093725 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  HHM66_RS10355 (HHM66_10380) spx 2093837..2094235 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  HHM66_RS10360 (HHM66_10385) - 2094484..2095967 (-) 1484 Protein_1998 IS1182 family transposase -
  HHM66_RS10365 (HHM66_10390) recA 2096083..2097219 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  HHM66_RS10370 (HHM66_10395) cinA 2097324..2098595 (-) 1272 WP_015058134.1 competence/damage-inducible protein A Machinery gene
  HHM66_RS10375 (HHM66_10400) - 2098719..2099072 (-) 354 WP_003058738.1 VOC family protein -
  HHM66_RS10380 (HHM66_10405) - 2099075..2099647 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  HHM66_RS10385 (HHM66_10410) ruvA 2099657..2100250 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA -
  HHM66_RS10390 (HHM66_10415) - 2100252..2101472 (-) 1221 WP_014612636.1 MFS transporter -
  HHM66_RS10395 (HHM66_10420) mutL 2101483..2103465 (-) 1983 WP_015058135.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46035.47 Da        Isoelectric Point: 4.7637

>NTDB_id=442805 HHM66_RS10370 WP_015058134.1 2097324..2098595(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDAFYASRKESSRTANNVKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPFLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFSGASQVFNGGFVTYSMEEKARM
LGIPLEDLISHGVVSAYTAEKMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQNKVESIKVLISGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=442805 HHM66_RS10370 WP_015058134.1 2097324..2098595(-) (cinA) [Streptococcus dysgalactiae subsp. equisimilis strain TPCH-A88]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGATGCTTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGTTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTTTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGATCCTACTATTGCACCTTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACTGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTTCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTGACTTATAGCATGGAAGAAAAAGCGAGAATG
CTAGGCATTCCTTTAGAGGATTTGATATCGCATGGAGTTGTTAGTGCTTATACGGCCGAGAAGATGGCGGAGCAAGCAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGAACAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATAAAGGTTTTGATTAGCGGGCGAAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAATATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.577

100

0.726
  cinA Streptococcus mitis SK321

70.983

98.582

0.7
  cinA Streptococcus mitis NCTC 12261

70.024

98.582

0.69
  cinA Streptococcus pneumoniae TIGR4

69.784

98.582

0.688
  cinA Streptococcus pneumoniae Rx1

69.784

98.582

0.688
  cinA Streptococcus pneumoniae R6

69.784

98.582

0.688
  cinA Streptococcus pneumoniae D39

69.544

98.582

0.686
  cinA Streptococcus suis isolate S10

52.644

98.345

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449