Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HIR79_RS12275 Genome accession   NZ_CP053032
Coordinates   2595948..2597183 (+) Length   411 a.a.
NCBI ID   WP_169958583.1    Uniprot ID   A0A6M4FWG0
Organism   Halomonas sp. PGE1     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2590948..2602183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIR79_RS12250 (HIR79_12260) - 2591339..2592781 (-) 1443 WP_169958578.1 MBL fold metallo-hydrolase -
  HIR79_RS12255 (HIR79_12265) - 2593110..2593256 (+) 147 WP_169958579.1 hypothetical protein -
  HIR79_RS12260 (HIR79_12270) - 2593367..2593792 (+) 426 WP_169958580.1 nucleotidyltransferase domain-containing protein -
  HIR79_RS12265 (HIR79_12275) - 2593782..2594003 (+) 222 WP_169958581.1 HepT-like ribonuclease domain-containing protein -
  HIR79_RS12270 (HIR79_12280) pilB 2594096..2595895 (+) 1800 WP_169958582.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HIR79_RS12275 (HIR79_12285) pilC 2595948..2597183 (+) 1236 WP_169958583.1 type II secretion system F family protein Machinery gene
  HIR79_RS12280 (HIR79_12290) pilD 2597205..2598053 (+) 849 WP_169959573.1 A24 family peptidase Machinery gene
  HIR79_RS12285 (HIR79_12295) - 2598186..2598764 (-) 579 WP_119020348.1 hypoxanthine-guanine phosphoribosyltransferase -
  HIR79_RS12290 (HIR79_12300) nagZ 2598810..2599817 (-) 1008 WP_169958584.1 beta-N-acetylhexosaminidase -
  HIR79_RS12295 (HIR79_12310) - 2599962..2600675 (-) 714 WP_249322141.1 TetR/AcrR family transcriptional regulator -
  HIR79_RS12300 (HIR79_12315) lexA 2600896..2601546 (+) 651 WP_169958585.1 transcriptional repressor LexA -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 44894.80 Da        Isoelectric Point: 10.0819

>NTDB_id=442324 HIR79_RS12275 WP_169958583.1 2595948..2597183(+) (pilC) [Halomonas sp. PGE1]
MATARKLRPAKEIKLYRWRWTGKGPGGRKVGGEIVAAQKGEVEKILAGQNIIIKNVRRKGGFGGGMGKIKPRDIMLFARQ
MATMIRAGVPVLQAFQVVAESIKKPAMSGLVQELMNDVAAGASFSDALKRHPQHFDRLFANLVEAGEQSGSLDRMLDRVA
TYKEKIELLKGRVKKALWYPAAVIAVGIGVTALLLIKVVPQFESLFQGFGAELPAMTRMTIAMSEFAQAYWWWGVLGIAA
FIFFIRTGMKKSEAFAYRMHAFALKVPVLGEILDKSAVARYSRTLATTFGAGVPLVEALDTAAGATGNKVYERAVAQIRE
DVATGQQLNFAMRMTEQFPPLAVQMVGIGEESGALDAMLNRVADYYEEEVDNMVDTLTSLLEPFIIVVLGVLVGGLVISM
YLPIFELGSVI

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=442324 HIR79_RS12275 WP_169958583.1 2595948..2597183(+) (pilC) [Halomonas sp. PGE1]
ATGGCCACAGCACGGAAATTGCGCCCCGCCAAGGAGATCAAGCTCTACCGCTGGCGCTGGACAGGCAAGGGCCCCGGCGG
TCGCAAGGTGGGGGGGGAGATCGTCGCCGCCCAGAAGGGCGAGGTGGAGAAGATCCTCGCCGGCCAGAACATCATCATCA
AGAACGTGCGCCGCAAGGGCGGCTTCGGCGGCGGCATGGGCAAGATCAAGCCCCGCGACATCATGCTCTTCGCCCGCCAG
ATGGCCACCATGATCCGCGCCGGGGTGCCGGTGCTGCAGGCCTTCCAGGTGGTGGCAGAGAGCATCAAGAAGCCGGCCAT
GAGCGGCCTGGTGCAGGAGCTGATGAACGACGTGGCCGCCGGCGCCTCGTTTTCCGACGCGCTGAAGCGCCACCCACAGC
ATTTCGATCGGCTGTTTGCCAACCTGGTGGAGGCCGGCGAGCAGTCCGGCTCGCTGGACCGCATGCTCGACCGGGTGGCC
ACCTACAAGGAGAAGATCGAGCTGCTCAAGGGGCGCGTGAAGAAGGCGCTCTGGTACCCGGCGGCGGTGATAGCGGTGGG
CATCGGCGTCACCGCCCTGCTCTTGATCAAGGTGGTGCCGCAGTTCGAGAGCCTGTTCCAGGGCTTCGGCGCGGAGCTGC
CCGCCATGACCCGCATGACCATTGCCATGTCCGAGTTCGCCCAGGCCTACTGGTGGTGGGGGGTGCTCGGCATCGCGGCC
TTCATTTTCTTCATCCGCACCGGCATGAAGAAGTCCGAGGCCTTCGCCTACCGCATGCACGCCTTCGCCTTGAAGGTGCC
GGTACTGGGGGAGATCCTCGATAAATCCGCGGTAGCGCGCTACTCGCGCACCCTGGCCACCACCTTCGGCGCCGGCGTGC
CCCTGGTGGAGGCGCTGGACACTGCCGCCGGCGCCACCGGCAACAAGGTCTACGAGCGCGCGGTGGCGCAGATCCGCGAG
GACGTGGCCACCGGCCAGCAGCTCAACTTCGCCATGCGCATGACCGAGCAGTTCCCGCCGCTGGCGGTGCAAATGGTCGG
CATCGGGGAGGAGTCCGGCGCGCTGGACGCCATGCTCAACCGGGTGGCGGACTACTACGAGGAGGAGGTCGACAACATGG
TCGACACCCTCACCTCGCTGCTGGAGCCCTTCATCATCGTGGTGCTGGGCGTGCTGGTGGGCGGGCTCGTTATCTCCATG
TACCTGCCGATCTTCGAGCTGGGCAGCGTGATCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-403)

Type II secretion system (T2SS), protein F (T2SSF)

(77-200)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M4FWG0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

54.591

98.054

0.535
  pilC Acinetobacter baylyi ADP1

53.401

96.594

0.516
  pilC Acinetobacter baumannii D1279779

52.897

96.594

0.511
  pilC Legionella pneumophila strain ERS1305867

52.369

97.567

0.511
  pilC Vibrio cholerae strain A1552

43.627

99.27

0.433
  pilC Vibrio campbellii strain DS40M4

43.672

98.054

0.428
  pilG Neisseria meningitidis 44/76-A

42.424

96.35

0.409
  pilG Neisseria gonorrhoeae MS11

42.424

96.35

0.409