Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CA267_RS04040 Genome accession   NZ_CP052766
Coordinates   867025..868236 (+) Length   403 a.a.
NCBI ID   WP_075608677.1    Uniprot ID   A0A6M4MBM5
Organism   Alteromonas pelagimontana strain 5.12     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 862025..873236
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA267_RS04010 (CA267_004015) - 862254..863000 (-) 747 WP_075608683.1 GntR family transcriptional regulator -
  CA267_RS04015 (CA267_004020) ampE 863261..864130 (-) 870 WP_075608682.1 beta-lactamase regulator AmpE -
  CA267_RS04020 (CA267_004025) ampD 864127..864702 (-) 576 WP_075608681.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CA267_RS04025 (CA267_004030) - 864854..865357 (+) 504 WP_075608680.1 TIGR02281 family clan AA aspartic protease -
  CA267_RS04030 (CA267_004035) nadC 865379..866239 (+) 861 WP_075608679.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CA267_RS04035 (CA267_004040) - 866490..866924 (+) 435 WP_075608678.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  CA267_RS04040 (CA267_004045) pilC 867025..868236 (+) 1212 WP_075608677.1 type II secretion system F family protein Machinery gene
  CA267_RS04045 (CA267_004050) pilD 868327..869256 (+) 930 WP_075608676.1 A24 family peptidase Machinery gene
  CA267_RS04050 (CA267_004055) coaE 869256..869891 (+) 636 WP_075608675.1 dephospho-CoA kinase -
  CA267_RS04055 (CA267_004060) zapD 870369..871121 (+) 753 WP_075608674.1 cell division protein ZapD -
  CA267_RS04060 (CA267_004065) yacG 871200..871430 (+) 231 WP_075608673.1 DNA gyrase inhibitor YacG -
  CA267_RS04065 (CA267_004070) - 871544..872410 (+) 867 WP_075608672.1 aspartoacylase -
  CA267_RS04070 (CA267_004075) mutT 872589..872993 (-) 405 WP_075608671.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 403 a.a.        Molecular weight: 43613.23 Da        Isoelectric Point: 9.9694

>NTDB_id=441535 CA267_RS04040 WP_075608677.1 867025..868236(+) (pilC) [Alteromonas pelagimontana strain 5.12]
MAKAATTFTWQGKDKQGSNRKGEISATSLSEAKNLLRRQGISAQKVRKLATPLFGRGGKKITAADISVVSRQIATMLSAG
VTLIQSLDMIAQGHGKPSMRKLLGEITNEVRAGTPLSTALRKHPDYFDDLYCDLVHTGEQSGALETIYDRIATYKEKAEA
LKSKIKKAMFYPIAVVVVAFIVTTILLVFVVPQFEEIFSSFGAELPAFTQFVLGISRFVQDYGIFIGMGIAGAIFLFFRT
HKKSLKFRDKMDKLSLKIPVIGNILKKASIARFTRTLATTFAAGVPLIGALDSAAGASGNAVYRDAILYVKKEVAGGLQM
NTAMRATNVFPDMVTQMVAIGEESGAVDEMLSKIATIYEAEVDDMVDGLTSLLEPMIMAVLGVVIGGLIIAMYLPIFQMG
NVV

Nucleotide


Download         Length: 1212 bp        

>NTDB_id=441535 CA267_RS04040 WP_075608677.1 867025..868236(+) (pilC) [Alteromonas pelagimontana strain 5.12]
ATGGCGAAAGCAGCAACGACATTTACCTGGCAAGGTAAAGATAAGCAAGGCAGCAACCGTAAAGGTGAAATTTCTGCGAC
TTCGTTGTCTGAGGCGAAAAACCTGTTGCGTCGGCAGGGCATTTCCGCACAAAAGGTAAGAAAGCTAGCTACGCCTTTAT
TCGGGCGCGGCGGTAAAAAAATTACTGCCGCCGACATCTCCGTAGTCTCCCGTCAAATTGCCACTATGCTAAGCGCGGGG
GTCACCCTGATTCAATCGTTGGATATGATAGCTCAGGGTCACGGCAAACCGTCGATGCGCAAATTATTGGGTGAGATTAC
CAACGAAGTCAGGGCCGGCACGCCGTTGTCTACAGCGCTGCGCAAACATCCGGACTATTTCGACGATCTGTATTGCGACT
TGGTGCACACTGGCGAACAATCTGGTGCGCTCGAAACTATCTACGACCGTATCGCTACCTATAAAGAAAAAGCCGAAGCG
CTGAAATCAAAAATCAAAAAGGCGATGTTCTACCCTATTGCGGTGGTGGTGGTGGCATTTATTGTTACCACCATACTCTT
AGTATTTGTGGTACCTCAGTTTGAAGAAATATTCAGTAGCTTTGGTGCTGAACTGCCCGCCTTCACACAGTTTGTATTAG
GAATTTCCCGGTTTGTGCAAGACTACGGAATTTTTATTGGTATGGGCATCGCTGGCGCTATTTTTCTGTTTTTCCGCACC
CACAAGAAATCGCTTAAATTCAGAGACAAGATGGATAAGCTTTCGCTAAAAATTCCGGTAATTGGCAATATACTAAAAAA
AGCCAGTATTGCGCGCTTTACCCGTACCCTTGCTACCACTTTTGCTGCGGGCGTACCCCTTATTGGCGCGCTGGATTCAG
CCGCTGGCGCATCGGGAAACGCGGTTTATCGTGATGCCATTCTCTATGTAAAAAAGGAAGTCGCCGGCGGGCTACAGATG
AATACTGCAATGCGGGCTACCAATGTGTTCCCTGACATGGTGACGCAGATGGTAGCAATTGGCGAGGAATCAGGCGCGGT
AGATGAAATGCTAAGTAAAATAGCCACCATTTACGAAGCCGAAGTGGATGATATGGTTGACGGCCTCACCAGCTTACTGG
AACCCATGATAATGGCGGTGCTGGGGGTAGTCATCGGCGGGTTGATTATAGCTATGTACTTACCCATCTTCCAGATGGGA
AATGTGGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(70-192)

Type II secretion system (T2SS), protein F (T2SSF)

(273-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M4MBM5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

60.553

98.759

0.598
  pilC Acinetobacter baumannii D1279779

53.846

100

0.538
  pilC Acinetobacter baylyi ADP1

53.401

98.511

0.526
  pilC Legionella pneumophila strain ERS1305867

52.393

98.511

0.516
  pilC Vibrio cholerae strain A1552

47.103

98.511

0.464
  pilG Neisseria meningitidis 44/76-A

43.672

100

0.437
  pilC Vibrio campbellii strain DS40M4

44.081

98.511

0.434
  pilG Neisseria gonorrhoeae MS11

43.424

100

0.434
  pilC Thermus thermophilus HB27

37.562

99.752

0.375