Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   AHBrac6_RS19760 Genome accession   NZ_CP050850
Coordinates   4327714..4328955 (+) Length   413 a.a.
NCBI ID   WP_206818892.1    Uniprot ID   -
Organism   Aeromonas hydrophila strain Brac6     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4322714..4333955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AHBrac6_RS19735 (AHBrac6_19770) ampD 4323093..4323665 (-) 573 WP_206818889.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  AHBrac6_RS19740 (AHBrac6_19775) - 4323813..4324283 (+) 471 WP_206818890.1 retropepsin-like aspartic protease -
  AHBrac6_RS19745 (AHBrac6_19780) nadC 4324289..4325146 (+) 858 WP_206818891.1 carboxylating nicotinate-nucleotide diphosphorylase -
  AHBrac6_RS19750 (AHBrac6_19785) tapA 4325469..4325885 (+) 417 WP_042066959.1 type IVa pilus major pilin TapA -
  AHBrac6_RS19755 (AHBrac6_19790) pilB 4325892..4327598 (+) 1707 WP_029302067.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  AHBrac6_RS19760 (AHBrac6_19795) pilC 4327714..4328955 (+) 1242 WP_206818892.1 type II secretion system F family protein Machinery gene
  AHBrac6_RS19765 (AHBrac6_19800) pilD 4328978..4329850 (+) 873 WP_206818893.1 A24 family peptidase Machinery gene
  AHBrac6_RS19770 (AHBrac6_19805) coaE 4329869..4330483 (+) 615 WP_206818894.1 dephospho-CoA kinase -
  AHBrac6_RS19775 (AHBrac6_19810) zapD 4330521..4331243 (+) 723 WP_206818895.1 cell division protein ZapD -
  AHBrac6_RS19780 (AHBrac6_19815) yacG 4331253..4331447 (+) 195 WP_005305661.1 DNA gyrase inhibitor YacG -
  AHBrac6_RS19785 (AHBrac6_19820) mutT 4331508..4331921 (-) 414 WP_016352173.1 8-oxo-dGTP diphosphatase MutT -
  AHBrac6_RS19790 (AHBrac6_19825) - 4331930..4333114 (-) 1185 WP_206818896.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45468.60 Da        Isoelectric Point: 9.8637

>NTDB_id=435250 AHBrac6_RS19760 WP_206818892.1 4327714..4328955(+) (pilC) [Aeromonas hydrophila strain Brac6]
MATLTQKQNAPKKVFAFRWSGVNRKGQKVSGELQADSINTVKAELRKQGVNVTKVSKKSQGIFSKGGAKIKPMDIAVVSR
QITTMLSAGVPLVQSLQIIARSHEKAAMRELMGQIAADVETGTPMSEALRRHPRHFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPIFTQFVIGISRFMQNWWYVIFGSIA
LSIFLYVRAWRASQKVKDNTDKFILTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=435250 AHBrac6_RS19760 WP_206818892.1 4327714..4328955(+) (pilC) [Aeromonas hydrophila strain Brac6]
ATGGCAACGCTAACCCAGAAACAGAATGCCCCCAAGAAAGTCTTCGCCTTTCGCTGGAGCGGGGTTAATCGCAAGGGCCA
GAAGGTCTCCGGCGAATTGCAGGCCGACAGCATCAACACGGTCAAGGCAGAGCTGCGCAAACAGGGTGTCAACGTCACCA
AGGTGAGCAAGAAGAGCCAGGGGATCTTCTCCAAGGGCGGCGCCAAGATCAAGCCGATGGACATCGCCGTCGTCTCCCGC
CAGATCACCACCATGTTGTCAGCCGGTGTACCTCTGGTCCAGAGCCTGCAGATCATCGCTCGCAGCCACGAGAAGGCGGC
CATGCGCGAGCTCATGGGCCAGATTGCCGCCGATGTGGAGACCGGCACGCCCATGTCCGAGGCACTGCGCCGCCATCCCC
GTCACTTTGACGATCTCTATTGCGATCTGGTGGAGGCTGGCGAGCAGTCCGGCGCTCTGGAGACCATCTACGATCGCATC
GCCACCTATCGCGAGAAATCGGAAGCACTCAAGTCCAAGATCAAGAAAGCCATGTTTTACCCCACCATGGTCATCCTGGT
GGCCATTGTCGTTACCTCCATCCTGCTACTGTTTGTCATTCCCCAGTTCGAGGACATCTTCAAGAGCTTCGGTGCCGAGC
TGCCCATCTTTACCCAGTTTGTCATCGGCATCTCCCGTTTCATGCAGAACTGGTGGTATGTGATCTTTGGCAGCATAGCG
CTTTCCATCTTTCTCTACGTGCGCGCCTGGCGCGCCTCCCAGAAGGTCAAGGACAACACCGACAAGTTCATACTGACCAT
CCCCGTGGTCGGCATGATATTGCACAAGGCCGCCATGGCCCGTTTCGCCCGTACCCTCTCCACCACCTTCTCTGCCGGTA
TCCCGCTGGTAGATGCCTTGGTTTCTGCAGCTGGCGCCTCCGGCAACTATGTCTACCGTACTGCCGTCATGGCCATTCGC
AACGAGGTGGTGGCCGGCATGCAGATCAACGTGGCCATGCGCACCGTCGATCTGTTCCCGGACATGGTGATCCAGATGGT
GATGATCGGCGAGGAGTCTGGCGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGACGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCTCTCATCATGGTGGTGCTGGGGGTTCTGGTCGGCGGCATGGTGGTCGCC
ATGTATCTGCCCATCTTCAAACTGGGGTCGGTGATCCACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.566

95.884

0.542
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.141

96.126

0.501
  pilC Legionella pneumophila strain ERS1305867

51.111

98.063

0.501
  pilC Vibrio cholerae strain A1552

47.487

96.368

0.458
  pilC Vibrio campbellii strain DS40M4

46.348

96.126

0.446
  pilG Neisseria gonorrhoeae MS11

39.552

97.337

0.385
  pilG Neisseria meningitidis 44/76-A

39.303

97.337

0.383
  pilC Thermus thermophilus HB27

37.5

96.852

0.363