Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HC168_RS02385 Genome accession   NZ_CP050789
Coordinates   469067..470308 (-) Length   413 a.a.
NCBI ID   WP_106885656.1    Uniprot ID   A0AAP4J3C9
Organism   Aeromonas media strain FiBL-4043     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 464067..475308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HC168_RS02360 (HC168_02360) mutT 466040..466444 (+) 405 WP_111911126.1 8-oxo-dGTP diphosphatase MutT -
  HC168_RS02365 (HC168_02365) yacG 466517..466711 (-) 195 WP_025328449.1 DNA gyrase inhibitor YacG -
  HC168_RS02370 (HC168_02370) zapD 466721..467443 (-) 723 WP_162520171.1 cell division protein ZapD -
  HC168_RS02375 (HC168_02375) coaE 467481..468095 (-) 615 WP_404835798.1 dephospho-CoA kinase -
  HC168_RS02380 (HC168_02380) pilD 468114..468986 (-) 873 WP_395949383.1 prepilin peptidase Machinery gene
  HC168_RS02385 (HC168_02385) pilC 469067..470308 (-) 1242 WP_106885656.1 type II secretion system F family protein Machinery gene
  HC168_RS02390 (HC168_02390) pilB 470439..472145 (-) 1707 WP_395949384.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  HC168_RS02395 (HC168_02395) - 472149..472583 (-) 435 WP_395949385.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  HC168_RS02400 (HC168_02400) nadC 472896..473759 (-) 864 WP_395949386.1 carboxylating nicotinate-nucleotide diphosphorylase -
  HC168_RS02405 (HC168_02405) - 473763..474233 (-) 471 WP_111911112.1 TIGR02281 family clan AA aspartic protease -
  HC168_RS02410 (HC168_02410) ampD 474370..474942 (+) 573 WP_111911110.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45345.33 Da        Isoelectric Point: 9.9044

>NTDB_id=434750 HC168_RS02385 WP_106885656.1 469067..470308(-) (pilC) [Aeromonas media strain FiBL-4043]
MATLAQKQNAPKKVFSFRWHGVNRKGQKVSGELQADSITTVKAELRKQGVNVTRVSKQGQGMFSKGGARIKPMDIAVISR
QITTMLSAGVPLVQSLQIIARGHEKAAVRELIGQIAADVETGTPLSDALRRHPRHFDALYCDLVEAGEQSGALETIYDRI
AIYREKSEALKSKIKKAMFYPAMVILVAIIVTSILLLFVIPQFEEIFKSFGAELPAFTRFIIAISRFMQDWWYAIFGGIA
LTVFLYVRAWRSSQKVRDNTDKFILSIPVVGNILHKAAMARFARTLSTTFSAGIPLVDALVSAAGASGNYVYRTATLAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVAAIFEQEVDDMVDGLTSLLEPIIMVVLGVLVGGMVVA
MYLPIFKLGSVIH

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=434750 HC168_RS02385 WP_106885656.1 469067..470308(-) (pilC) [Aeromonas media strain FiBL-4043]
ATGGCTACATTAGCTCAAAAACAAAACGCACCAAAAAAGGTCTTCTCCTTCCGCTGGCACGGCGTCAATCGCAAGGGACA
AAAGGTTTCCGGTGAGTTGCAAGCCGACAGCATCACGACAGTCAAGGCGGAGCTGCGCAAGCAGGGCGTCAATGTCACCA
GGGTCAGCAAGCAGGGCCAGGGAATGTTTTCCAAGGGCGGCGCCAGGATCAAGCCGATGGACATCGCCGTCATCTCCCGC
CAGATCACCACCATGCTCTCTGCCGGCGTGCCGCTGGTGCAGAGCCTGCAGATCATTGCCCGTGGCCATGAAAAGGCGGC
GGTGCGCGAGCTGATCGGCCAGATCGCCGCCGATGTGGAGACAGGCACCCCCCTGTCAGATGCGCTGCGCCGCCACCCCC
GCCACTTCGATGCCCTCTACTGTGACCTGGTGGAGGCGGGGGAGCAGTCAGGCGCGCTGGAAACCATCTACGACCGGATT
GCCATCTATCGCGAGAAGAGCGAGGCGCTCAAATCCAAGATCAAGAAGGCCATGTTCTATCCCGCCATGGTCATCCTGGT
CGCCATCATAGTGACCTCCATACTGTTGCTGTTCGTCATCCCCCAGTTCGAAGAGATCTTCAAGAGCTTCGGGGCCGAGC
TGCCCGCCTTCACCCGATTCATCATTGCCATCTCCCGCTTCATGCAGGATTGGTGGTACGCCATCTTCGGCGGCATAGCC
CTGACAGTATTCCTCTATGTGCGCGCCTGGCGCAGCTCCCAGAAGGTACGTGACAACACCGACAAGTTCATCCTCTCCAT
TCCAGTCGTTGGCAACATACTGCACAAGGCGGCCATGGCCCGTTTCGCCCGCACCCTCTCCACCACCTTCTCCGCCGGTA
TTCCCCTGGTGGATGCCCTGGTCTCCGCTGCCGGGGCCTCGGGCAACTATGTCTATCGCACGGCTACCCTGGCCATTCGC
AACGAAGTCGTGGCTGGCATGCAGATCAACGTCGCCATGCGCACCGTGGATCTTTTCCCCGACATGGTGATCCAGATGGT
GATGATAGGTGAAGAGTCCGGCGCCATCGACGACATGCTCTCCAAGGTCGCCGCCATCTTCGAGCAGGAGGTGGACGACA
TGGTCGATGGTCTCACCAGCCTGCTCGAGCCCATCATAATGGTGGTGCTGGGGGTGCTGGTCGGCGGCATGGTCGTCGCC
ATGTACCTCCCCATCTTCAAGCTGGGCTCTGTGATACACTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

55.303

95.884

0.53
  pilC Legionella pneumophila strain ERS1305867

51.605

98.063

0.506
  pilC Acinetobacter baumannii D1279779

51.87

97.094

0.504
  pilC Acinetobacter baylyi ADP1

50.882

96.126

0.489
  pilC Vibrio cholerae strain A1552

46.192

98.547

0.455
  pilC Vibrio campbellii strain DS40M4

44.802

97.821

0.438
  pilG Neisseria meningitidis 44/76-A

40.247

98.063

0.395
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilC Thermus thermophilus HB27

38

96.852

0.368