Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HBA50_RS00025 Genome accession   NZ_CP050133
Coordinates   3949..5127 (-) Length   392 a.a.
NCBI ID   WP_045499890.1    Uniprot ID   A0AAW5WNQ6
Organism   Streptococcus cristatus ATCC 51100     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1..10127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS00010 (HBA50_00010) dnaN 263..1399 (-) 1137 WP_045499880.1 DNA polymerase III subunit beta -
  HBA50_RS00015 (HBA50_00015) dnaA 1557..2912 (-) 1356 WP_045499883.1 chromosomal replication initiator protein DnaA -
  HBA50_RS00020 (HBA50_00020) spo0J 3125..3886 (-) 762 WP_045499887.1 ParB/RepB/Spo0J family partition protein Regulator
  HBA50_RS00025 (HBA50_00025) htrA 3949..5127 (-) 1179 WP_045499890.1 S1C family serine protease Regulator
  HBA50_RS00030 (HBA50_00030) rlmH 5330..5809 (+) 480 WP_045499893.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HBA50_RS00040 (HBA50_00040) comC 6103..6228 (+) 126 WP_045499896.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  HBA50_RS00045 (HBA50_00045) comD/comD2 6251..7576 (+) 1326 WP_045499899.1 GHKL domain-containing protein Regulator
  HBA50_RS00050 (HBA50_00050) comE/comE2 7573..8316 (+) 744 WP_045499902.1 competence system response regulator transcription factor ComE Regulator
  HBA50_RS00065 (HBA50_00065) - 8683..10077 (+) 1395 WP_166492625.1 IS1182 family transposase -

Sequence

Protein


Download         Length: 392 a.a.        Molecular weight: 41362.51 Da        Isoelectric Point: 5.8393

>NTDB_id=430180 HBA50_RS00025 WP_045499890.1 3949..5127(-) (htrA) [Streptococcus cristatus ATCC 51100]
MKNASNFFKKSLLLFIVLVVGFIGGSLGNLATAFLNNKMANISPSSSKTTVSTSYKNTTDTTKAVKKVQNAVVSVITYTG
SNQEGVINNESTSDPQVASEGSGVIYKKEGKYAYLVTNTHVLNGAKNPDILLADGSKVPGEVVGSDVYSDISVVRISSEK
VKDVAEFGDSNSLTVGETAIAIGSPLGTEYANSVTQGIISSLGRNVTLQSEDGQNISTTALQTDAAINPGNSGGPLINIQ
GQVIGITSSKISHNGQTAVEGMGFAIPSNDVVNIIKQLEKNGTVTRPALGIQMLDLSNIATSDLAKLRLPSSVKSGILVR
SVQEGMPAENKLQKYDVITKVDDKDVESTSDLQSALYRHSLGDELKVTYFRDGKEATTTIKLTKSTQDLSDN

Nucleotide


Download         Length: 1179 bp        

>NTDB_id=430180 HBA50_RS00025 WP_045499890.1 3949..5127(-) (htrA) [Streptococcus cristatus ATCC 51100]
ATGAAAAACGCTTCAAATTTCTTTAAAAAATCTTTGTTGCTTTTTATTGTTTTAGTTGTAGGATTTATTGGCGGAAGCCT
AGGAAATTTAGCCACTGCATTTCTTAATAATAAAATGGCTAATATTAGCCCTTCTAGCTCAAAGACCACTGTATCAACGT
CTTATAAAAATACAACCGACACCACAAAGGCTGTAAAAAAGGTGCAAAATGCAGTTGTATCAGTAATTACTTATACAGGT
TCTAATCAGGAAGGAGTGATCAATAATGAATCAACCAGTGATCCTCAAGTAGCTAGTGAGGGATCAGGTGTCATTTATAA
GAAGGAAGGAAAATATGCCTACCTTGTTACCAATACTCACGTGCTAAATGGAGCAAAAAATCCCGATATTCTACTAGCAG
ATGGTAGTAAGGTTCCTGGTGAAGTAGTGGGGTCAGATGTTTATTCTGATATTTCTGTAGTAAGAATTAGCTCTGAAAAG
GTGAAAGATGTAGCTGAATTTGGAGATTCCAACTCCCTGACAGTAGGAGAAACTGCTATTGCTATCGGAAGCCCTCTCGG
AACAGAATATGCTAACTCTGTTACACAAGGAATCATCTCTAGTTTGGGTAGAAATGTAACCTTGCAATCTGAAGACGGCC
AAAATATTTCGACGACTGCCTTGCAAACAGATGCTGCTATCAACCCTGGTAACTCTGGTGGCCCACTCATCAATATCCAA
GGGCAAGTTATTGGTATTACGTCCAGCAAAATCTCTCACAATGGTCAAACTGCTGTAGAAGGCATGGGCTTTGCAATTCC
ATCAAACGATGTTGTCAATATTATCAAGCAACTAGAGAAAAATGGAACAGTGACTCGTCCTGCTCTGGGTATCCAAATGC
TCGATTTATCTAATATCGCCACTTCTGACTTAGCAAAATTACGTCTGCCTTCATCTGTAAAATCAGGTATCCTTGTCCGC
TCTGTACAAGAAGGAATGCCTGCTGAAAATAAACTTCAGAAATACGACGTCATCACAAAAGTTGACGATAAGGATGTCGA
GTCAACCAGTGATTTACAATCTGCTCTCTACAGACACTCTCTGGGAGATGAACTGAAAGTGACTTACTTTAGAGATGGTA
AAGAAGCTACTACAACCATCAAATTGACCAAATCAACCCAGGACTTAAGTGACAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(287-382)

Trypsin-like peptidase domain (Trypsin_2)

(101-246)

Peptidase family M50 (Peptidase_M50)

(233-386)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

68.101

100

0.686
  htrA Streptococcus mitis NCTC 12261

64.45

99.745

0.643
  htrA Streptococcus pneumoniae Rx1

64.45

99.745

0.643
  htrA Streptococcus pneumoniae D39

64.45

99.745

0.643
  htrA Streptococcus pneumoniae R6

64.45

99.745

0.643
  htrA Streptococcus pneumoniae TIGR4

64.45

99.745

0.643
  htrA Streptococcus mutans UA159

55.473

100

0.569