Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   G7083_RS08505 Genome accession   NZ_CP049913
Coordinates   1741652..1742878 (-) Length   408 a.a.
NCBI ID   WP_166014380.1    Uniprot ID   A0A6G8D462
Organism   Vibrio sp. HDW18     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1736652..1747878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7083_RS08480 (G7083_08480) parC 1736722..1739007 (+) 2286 WP_166014375.1 DNA topoisomerase IV subunit A -
  G7083_RS08485 (G7083_08485) yacG 1739066..1739263 (-) 198 WP_166014376.1 DNA gyrase inhibitor YacG -
  G7083_RS08490 (G7083_08490) zapD 1739348..1740088 (-) 741 WP_166014377.1 cell division protein ZapD -
  G7083_RS08495 (G7083_08495) coaE 1740120..1740728 (-) 609 WP_166014378.1 dephospho-CoA kinase -
  G7083_RS08500 (G7083_08500) pilD 1740725..1741597 (-) 873 WP_166014379.1 A24 family peptidase Machinery gene
  G7083_RS08505 (G7083_08505) pilC 1741652..1742878 (-) 1227 WP_166014380.1 type II secretion system F family protein Machinery gene
  G7083_RS08510 (G7083_08510) pilB 1742913..1744601 (-) 1689 WP_166014381.1 type IV-A pilus assembly ATPase PilB Machinery gene
  G7083_RS08515 (G7083_08515) - 1744602..1745066 (-) 465 WP_166015021.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  G7083_RS08520 (G7083_08520) nadC 1745286..1746185 (-) 900 WP_166014382.1 carboxylating nicotinate-nucleotide diphosphorylase -
  G7083_RS08525 (G7083_08525) ampD 1746453..1747007 (+) 555 WP_166014383.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  G7083_RS08530 (G7083_08530) fldB 1747101..1747619 (-) 519 WP_166014384.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44729.86 Da        Isoelectric Point: 10.3505

>NTDB_id=428611 G7083_RS08505 WP_166014380.1 1741652..1742878(-) (pilC) [Vibrio sp. HDW18]
MQASKSVALKHYRWKGINSNGKKVHGQLLALSELEVRDKLKEQHIQIKKLKKGSVSLLARLSHRVKGKDITLLTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKGVEAGTPLSKSMRTASSHFDSLYVDLVETGEMSGNLPDVFERLATYRE
KSEQLRAKVIKALIYPSMVVLVALGVSYLMLTMVIPEFEAMFSGFGAELPWFTQQVLKLSHWVQAYSGWALLAIGVALFG
LKTLRQKSLAVRLATSRLSLKMPVIGSVLAKASIAKFSRTLATSFAAGIPILASLKTTAKTAGNIHFEHAINQVHRDTAA
GVPMYIALRNTEAFPEMVLQMVMIGEESGQLDDMLNKVASIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=428611 G7083_RS08505 WP_166014380.1 1741652..1742878(-) (pilC) [Vibrio sp. HDW18]
ATGCAAGCGAGCAAATCTGTAGCCTTAAAACACTACCGCTGGAAAGGCATCAACAGTAACGGCAAAAAAGTCCACGGCCA
GTTACTGGCACTCAGCGAATTAGAAGTGCGTGACAAGCTCAAAGAGCAGCACATTCAGATCAAAAAACTCAAAAAAGGCA
GCGTCTCTTTACTGGCACGCCTTAGCCATCGAGTCAAAGGTAAAGACATCACCCTATTAACCCGCCAACTGGCTACCATG
CTCACCACTGGTGTACCGATTGTGCAAGCGCTCAAGTTGGTCGGCGATAACCATCGCAAAGCGGAGATGAAATCGATTCT
GGCGCAAATCACCAAAGGGGTTGAAGCGGGTACGCCACTCTCAAAATCGATGCGTACTGCCAGCTCGCATTTTGACAGCT
TGTACGTTGATTTGGTGGAAACCGGTGAAATGTCCGGTAATTTGCCGGATGTGTTTGAACGCTTGGCGACTTATCGGGAA
AAAAGTGAACAACTGCGCGCTAAAGTGATCAAAGCGCTGATTTACCCCAGTATGGTGGTATTAGTGGCGCTTGGCGTTTC
TTACCTAATGCTGACTATGGTGATCCCCGAATTTGAAGCGATGTTTAGCGGTTTTGGGGCGGAACTACCTTGGTTTACTC
AGCAAGTGCTCAAACTATCACACTGGGTACAAGCCTATAGTGGATGGGCATTACTGGCGATTGGCGTAGCACTCTTCGGG
CTCAAAACGCTACGCCAAAAATCATTGGCAGTGCGTTTAGCTACCAGTCGCCTCAGCCTGAAAATGCCGGTCATCGGCTC
AGTACTGGCCAAAGCCTCGATCGCCAAATTCAGCCGCACTCTCGCCACCAGCTTTGCCGCCGGTATTCCGATCCTCGCCA
GTTTAAAAACCACGGCCAAAACCGCAGGTAACATCCACTTTGAACACGCCATCAATCAAGTGCACCGCGATACGGCGGCC
GGGGTACCGATGTATATTGCGCTGCGCAATACTGAAGCGTTTCCGGAAATGGTGCTGCAAATGGTGATGATTGGCGAAGA
GTCAGGCCAGTTGGATGATATGCTGAATAAGGTCGCCAGCATCTACGAATTTGAAGTGGATAATACCGTGGATAATCTCG
GCAAAATCCTTGAGCCGCTGATCATTGTCTTTCTGGGCACTGTGGTGGGCGGCCTAGTGGTGGCGATGTACTTGCCGATC
TTTAACTTGATGAGTGTCTTAGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8D462

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

88.48

100

0.885
  pilC Vibrio campbellii strain DS40M4

72.5

98.039

0.711
  pilC Pseudomonas stutzeri DSM 10701

42.015

99.755

0.419
  pilC Legionella pneumophila strain ERS1305867

42.184

98.775

0.417
  pilC Acinetobacter baylyi ADP1

40.686

100

0.407
  pilC Acinetobacter baumannii D1279779

40.441

100

0.404
  pilG Neisseria gonorrhoeae MS11

40.547

98.529

0.4
  pilG Neisseria meningitidis 44/76-A

40.05

98.529

0.395