Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   G7079_RS12190 Genome accession   NZ_CP049872
Coordinates   2568326..2569597 (+) Length   423 a.a.
NCBI ID   WP_166057565.1    Uniprot ID   A0A6G7ZXD1
Organism   Thermomonas sp. HDW16     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2563326..2574597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G7079_RS12170 (G7079_12175) - 2563743..2564456 (-) 714 WP_166057561.1 class I SAM-dependent methyltransferase -
  G7079_RS12175 (G7079_12180) - 2564456..2565538 (-) 1083 WP_166057562.1 glycosyltransferase family 4 protein -
  G7079_RS12180 (G7079_12185) - 2565591..2566460 (-) 870 WP_166057563.1 glycosyltransferase family 2 protein -
  G7079_RS12185 (G7079_12190) pilB 2566590..2568314 (+) 1725 WP_166057564.1 type IV-A pilus assembly ATPase PilB Machinery gene
  G7079_RS12190 (G7079_12195) pilC 2568326..2569597 (+) 1272 WP_166057565.1 type II secretion system F family protein Machinery gene
  G7079_RS12195 (G7079_12200) pilD 2569598..2570461 (+) 864 WP_166057566.1 A24 family peptidase Machinery gene
  G7079_RS12200 (G7079_12205) coaE 2570498..2571109 (+) 612 WP_166057567.1 dephospho-CoA kinase -
  G7079_RS12205 (G7079_12210) - 2571085..2572059 (-) 975 WP_166057568.1 Nudix family hydrolase -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46524.22 Da        Isoelectric Point: 10.0552

>NTDB_id=428311 G7079_RS12190 WP_166057565.1 2568326..2569597(+) (pilC) [Thermomonas sp. HDW16]
MSAHRAAISKARTQAESRRLNPMVEFVWQGRDKRGIVMKGEQLAKNANLLRAELRKQGITPTVVKPKGKPLFGGGASRIK
PRDIAIFSRQLATMMKSGVPIVMALEIIAGGQKNPAMKKMVTGLRTEIESGASIYEALSLYPVQFDELYRNLVHAGESSG
VLETVLETIANYKENIESIKGKIKKALFYPTAIIAVAILICAVLLIYVVPVFKETFQSYGADLPAFTEFVFGISDIVVKW
WWLVGIVVMIAFGVFMFFYKRSDPLRHWIDRMMLKIPVIGQVLHNSSLARFARTLAVTFKAGVPLVEALGNVAGATGNTV
YEKAVLRMKNDVAVGYPLNMAMKQVNVFPHMVIQMTAIGEEAGALDTMLFKVAEFYEEEVNNAVDALSSLIEPAVMVIIG
GLVGSIVIAMYLPIFKIAMTVMG

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=428311 G7079_RS12190 WP_166057565.1 2568326..2569597(+) (pilC) [Thermomonas sp. HDW16]
ATGTCTGCACACCGAGCCGCTATCAGCAAGGCCAGGACCCAGGCGGAATCCCGCCGTTTGAACCCGATGGTGGAATTCGT
CTGGCAAGGCCGCGACAAGCGCGGCATCGTCATGAAGGGCGAACAACTGGCGAAAAATGCCAACTTGCTGCGCGCCGAGC
TGCGCAAGCAAGGCATCACCCCGACCGTGGTCAAACCCAAGGGCAAACCACTGTTCGGCGGTGGTGCCAGCCGGATCAAG
CCCCGTGATATCGCCATTTTCAGCCGCCAACTGGCCACCATGATGAAATCGGGCGTGCCCATCGTGATGGCGCTGGAAAT
CATCGCGGGTGGCCAGAAGAACCCTGCCATGAAAAAAATGGTCACGGGCCTGAGGACCGAGATCGAAAGTGGCGCCTCGA
TCTATGAGGCGCTGAGTCTGTATCCGGTGCAATTCGACGAGCTCTACCGCAACTTGGTGCACGCAGGCGAATCGTCAGGC
GTCTTGGAAACCGTCCTGGAGACGATTGCCAATTACAAAGAAAACATCGAATCGATCAAGGGCAAGATCAAGAAGGCATT
GTTCTATCCCACGGCCATCATCGCCGTGGCGATACTCATCTGCGCCGTCCTCCTGATCTACGTGGTTCCGGTTTTCAAGG
AAACCTTCCAGAGCTATGGCGCCGACCTGCCCGCGTTTACCGAATTCGTCTTTGGCATCTCCGACATCGTCGTCAAATGG
TGGTGGCTCGTTGGCATTGTCGTCATGATCGCCTTTGGCGTCTTCATGTTTTTCTACAAGCGATCGGATCCACTCAGGCA
CTGGATCGATCGGATGATGCTGAAGATCCCCGTGATCGGCCAAGTACTGCACAACTCCTCCCTCGCCCGCTTCGCCCGCA
CGCTGGCAGTGACGTTCAAGGCTGGTGTACCGCTGGTGGAGGCGCTGGGCAACGTGGCCGGCGCCACCGGCAATACGGTG
TATGAAAAGGCCGTATTGCGCATGAAGAATGACGTGGCCGTTGGTTATCCACTGAATATGGCGATGAAGCAGGTGAATGT
CTTCCCGCACATGGTGATCCAGATGACGGCCATCGGCGAAGAGGCCGGCGCGCTGGATACCATGTTGTTCAAGGTTGCCG
AGTTCTATGAGGAAGAGGTCAACAATGCCGTCGATGCACTGTCCAGCCTGATCGAGCCGGCGGTGATGGTGATCATTGGT
GGCCTGGTCGGCTCCATCGTCATCGCGATGTACCTGCCGATCTTCAAGATCGCCATGACGGTCATGGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(87-210)

Type II secretion system (T2SS), protein F (T2SSF)

(291-413)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G7ZXD1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

51.238

95.508

0.489
  pilC Acinetobacter baylyi ADP1

50

95.981

0.48
  pilC Pseudomonas stutzeri DSM 10701

51.01

93.617

0.478
  pilC Acinetobacter baumannii D1279779

48.148

95.745

0.461
  pilG Neisseria gonorrhoeae MS11

41.439

95.272

0.395
  pilG Neisseria meningitidis 44/76-A

41.191

95.272

0.392
  pilC Vibrio cholerae strain A1552

38.462

95.272

0.366
  pilC Vibrio campbellii strain DS40M4

38.404

94.799

0.364