Detailed information NTG0042583

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: SAEMRSA15_RS05850
• Genome accession: NC_017763
• Coordinates: 1213172..1213945 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus subsp. aureus HO 5096 0412
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1208172..1218945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAEMRSA15_RS05830 (SAEMRSA15_10840)	trmFO	1208516..1209823 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SAEMRSA15_RS05835 (SAEMRSA15_10850)	xerC	1210240..1211136 (+)	897	WP_001015609.1	tyrosine recombinase XerC	-
SAEMRSA15_RS05840 (SAEMRSA15_10860)	hslV	1211133..1211678 (+)	546	WP_000072678.1	ATP-dependent protease subunit HslV	-
SAEMRSA15_RS05845 (SAEMRSA15_10870)	hslU	1211744..1213147 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
SAEMRSA15_RS05850 (SAEMRSA15_10880)	codY	1213172..1213945 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
SAEMRSA15_RS05855	-	1213996..1214088 (+)	93	WP_031788481.1	hypothetical protein	-
SAEMRSA15_RS05860 (SAEMRSA15_10890)	rpsB	1214287..1215054 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
SAEMRSA15_RS05865	-	1215088..1215201 (+)	114	WP_001789890.1	hypothetical protein	-
SAEMRSA15_RS05870 (SAEMRSA15_10900)	tsf	1215236..1216117 (+)	882	WP_000201387.1	translation elongation factor Ts	-
SAEMRSA15_RS05875 (SAEMRSA15_10910)	pyrH	1216254..1216976 (+)	723	WP_000057330.1	UMP kinase	-
SAEMRSA15_RS05880 (SAEMRSA15_10920)	frr	1216995..1217549 (+)	555	WP_001280005.1	ribosome recycling factor	-
SAEMRSA15_RS05885 (SAEMRSA15_10930)	-	1217922..1218692 (+)	771	WP_000473699.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=42583 SAEMRSA15_RS05850 WP_000055337.1 1213172..1213945(+) (codY) [Staphylococcus aureus subsp. aureus HO 5096 0412]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=42583 SAEMRSA15_RS05850 WP_000055337.1 1213172..1213945(+) (codY) [Staphylococcus aureus subsp. aureus HO 5096 0412]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428