Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   D39N_RS08725 Genome accession   NZ_CP061208
Coordinates   1734246..1735502 (-) Length   418 a.a.
NCBI ID   WP_000642700.1    Uniprot ID   Q7ZAK3
Organism   Streptococcus pneumoniae strain D39_P0     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1729246..1740502
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D39N_RS08700 (D39N_01746) - 1729291..1729497 (-) 207 WP_000366091.1 hypothetical protein -
  D39N_RS08705 - 1729484..1729657 (-) 174 WP_000289349.1 helix-turn-helix transcriptional regulator -
  D39N_RS08710 (D39N_01747) lytA 1730016..1730972 (-) 957 WP_000405235.1 N-acetylmuramoyl-L-alanine amidase LytA -
  D39N_RS08715 (D39N_01748) - 1731348..1732718 (-) 1371 WP_001036271.1 MATE family efflux transporter -
  D39N_RS08720 (D39N_01749) recA 1733025..1734191 (-) 1167 WP_001085462.1 recombinase RecA -
  D39N_RS08725 (D39N_01750) cinA 1734246..1735502 (-) 1257 WP_000642700.1 competence/damage-inducible protein A Machinery gene
  D39N_RS08730 (D39N_01751) - 1735587..1736603 (-) 1017 WP_000239282.1 LCP family protein -
  D39N_RS08735 (D39N_01752) - 1736611..1737129 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  D39N_RS08740 (D39N_01753) tsaE 1737119..1737562 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  D39N_RS08745 (D39N_01754) comM 1737648..1738268 (-) 621 WP_000839908.1 hypothetical protein Regulator
  D39N_RS08750 (D39N_01755) - 1738651..1739514 (-) 864 WP_001093641.1 helix-turn-helix transcriptional regulator -
  D39N_RS10855 (D39N_01756) - 1739706..1739876 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  D39N_RS08755 (D39N_01757) pneA1 1739979..1740203 (+) 225 WP_000181087.1 two-peptide bacteriocin subunit PneA1 -
  D39N_RS08760 (D39N_01758) pneA2 1740210..1740398 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45036.36 Da        Isoelectric Point: 4.5211

>NTDB_id=420987 D39N_RS08725 WP_000642700.1 1734246..1735502(-) (cinA) [Streptococcus pneumoniae strain D39_P0]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGATEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=420987 D39N_RS08725 WP_000642700.1 1734246..1735502(-) (cinA) [Streptococcus pneumoniae strain D39_P0]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGGCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTGAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7ZAK3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae R36A

100

100

1
  cinA Streptococcus pneumoniae Rx1

100

100

1
  cinA Streptococcus pneumoniae R6

100

100

1
  cinA Streptococcus pneumoniae D39

99.761

100

0.998
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus mitis SK321

93.301

100

0.933
  cinA Streptococcus mitis NCTC 12261

93.062

100

0.931
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452