Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HMPREF0833_RS06870 Genome accession   NC_015678
Coordinates   1505471..1506739 (-) Length   422 a.a.
NCBI ID   WP_013904317.1    Uniprot ID   -
Organism   Streptococcus parasanguinis ATCC 15912     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1500471..1511739
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF0833_RS06840 (HMPREF0833_11397) - 1501852..1502157 (-) 306 WP_003001941.1 DUF1292 domain-containing protein -
  HMPREF0833_RS06845 (HMPREF0833_11398) ruvX 1502180..1502599 (-) 420 WP_003014525.1 Holliday junction resolvase RuvX -
  HMPREF0833_RS06850 (HMPREF0833_11399) - 1502599..1502865 (-) 267 WP_003002070.1 IreB family regulatory phosphoprotein -
  HMPREF0833_RS06855 (HMPREF0833_11400) - 1502989..1503585 (-) 597 WP_013904315.1 SP0191 family lipoprotein -
  HMPREF0833_RS06860 (HMPREF0833_11401) spx 1503720..1504118 (-) 399 WP_003009108.1 transcriptional regulator Spx -
  HMPREF0833_RS06865 (HMPREF0833_11402) recA 1504206..1505351 (-) 1146 WP_013904316.1 recombinase RecA Machinery gene
  HMPREF0833_RS06870 (HMPREF0833_11403) cinA 1505471..1506739 (-) 1269 WP_013904317.1 competence/damage-inducible protein A Machinery gene
  HMPREF0833_RS06875 (HMPREF0833_11404) - 1507112..1508143 (+) 1032 WP_013904318.1 S66 peptidase family protein -
  HMPREF0833_RS06880 (HMPREF0833_11405) - 1508206..1508769 (-) 564 WP_013904319.1 DNA-3-methyladenine glycosylase I -
  HMPREF0833_RS06885 (HMPREF0833_11406) ruvA 1508779..1509372 (-) 594 WP_013904320.1 Holliday junction branch migration protein RuvA -
  HMPREF0833_RS06890 (HMPREF0833_11407) mutL 1509393..1511336 (-) 1944 WP_041818388.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45145.26 Da        Isoelectric Point: 4.7346

>NTDB_id=41391 HMPREF0833_RS06870 WP_013904317.1 1505471..1506739(-) (cinA) [Streptococcus parasanguinis ATCC 15912]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLFSTIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDPTALAKLDTFFASRPDYVRTPNNERQAQMIAGSIPLQNRTGLAVGGLIEVDDVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEEQSDPTVAPYAKTGEVTLRLSTKAKDQASADAKLDVLEKEI
LSRHTLDHQPLHDLFYGYGDDNSMAKVAFDLLKQTGKTITAAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEGHPAGTVFIGLATPNGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=41391 HMPREF0833_RS06870 WP_013904317.1 1505471..1506739(-) (cinA) [Streptococcus parasanguinis ATCC 15912]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTGAACACCAATGCTCAATTCTTGTCTGA
AAAATTGGCTAGTTTAGGAATTGATGTCTATTATCATGTGGCGGTAGGAGACAATGAAGGCCGTCTCTTCTCGACCATTG
AGACAGCTTCAAAACGCAGTGATTTGGTGATTTTATGCGGTGGACTTGGGCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGAAAGAACTGGTTTTTGATCCGACAGCGCTTGCTAAACTCGACACCTTCTTTGCCAGTCGCCC
TGATTATGTCCGGACGCCCAATAATGAGCGACAAGCACAAATGATCGCCGGATCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGATGATGTGACCTATGTCGTTCTACCTGGTCCGCCAAGTGAGTTAAAACCCATG
GTCAATGAACAATTGGTGCCTCATTTGACAACAGGGGAACAGCTCTTTTCAAGAGTCTTGCGCTTCTTTGGGATTGGGGA
AAGCCAGCTGGTTACGATCCTAGCAGATATCATTGAAGAGCAGAGTGATCCGACGGTGGCCCCTTATGCCAAGACAGGAG
AAGTGACCTTGCGTCTGTCTACAAAGGCGAAGGATCAAGCCTCAGCGGATGCTAAGCTCGATGTCTTAGAAAAGGAAATC
TTATCACGCCACACCCTGGACCATCAACCCTTACACGACCTGTTTTACGGTTATGGGGATGACAATTCGATGGCCAAAGT
TGCCTTTGATCTTTTGAAACAGACTGGTAAGACTATTACAGCTGCAGAAAGCCTGACGGCTGGCCTCTTCCAAGCGACTC
TGGCAGATTTTTCAGGAGCGTCCAGCATCTTCGCGGGTGGTTTTGTCACCTATAGTTTGGAAGAAAAAAGCAAGATGTTG
TCCATTCCAGCTCAAGAGTTGGAGCAACATGGAGTAGTGTCTCATTTTACAGCTCAAGCCATGGCGTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCCTAACCGGAGTTGCGGGGCCAGATAGTCTAGAAGGGCATCCAGCAGGGACCG
TCTTTATCGGACTTGCGACTCCAAATGGAGTGGATAGTGTCCAAGTCAATATCGCTGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTTCTTCATGCCTTTAATTTGGTACGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.82

98.815

0.739
  cinA Streptococcus mitis NCTC 12261

74.58

98.815

0.737
  cinA Streptococcus pneumoniae TIGR4

73.621

98.815

0.727
  cinA Streptococcus pneumoniae Rx1

73.621

98.815

0.727
  cinA Streptococcus pneumoniae R6

73.621

98.815

0.727
  cinA Streptococcus pneumoniae D39

73.381

98.815

0.725
  cinA Streptococcus mutans UA159

70.686

100

0.709
  cinA Streptococcus suis isolate S10

55.69

97.867

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

47.229

98.341

0.464

Multiple sequence alignment