Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SGPB_RS09915 Genome accession   NC_015600
Coordinates   2019216..2020475 (-) Length   419 a.a.
NCBI ID   WP_013852328.1    Uniprot ID   F5X3T6
Organism   Streptococcus pasteurianus ATCC 43144     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2014216..2025475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGPB_RS11595 - 2015770..2015898 (-) 129 WP_259293846.1 hypothetical protein -
  SGPB_RS09890 (SGPB_1946) - 2015990..2016295 (-) 306 WP_003066884.1 DUF1292 domain-containing protein -
  SGPB_RS09895 (SGPB_1947) ruvX 2016328..2016747 (-) 420 WP_013852327.1 Holliday junction resolvase RuvX -
  SGPB_RS09900 (SGPB_1948) - 2016744..2017013 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  SGPB_RS09905 (SGPB_1949) spx 2017344..2017742 (-) 399 WP_003066893.1 transcriptional regulator Spx -
  SGPB_RS09910 (SGPB_1950) recA 2018012..2019166 (-) 1155 WP_009855165.1 recombinase RecA Machinery gene
  SGPB_RS09915 (SGPB_1951) cinA 2019216..2020475 (-) 1260 WP_013852328.1 competence/damage-inducible protein A Machinery gene
  SGPB_RS09920 (SGPB_1952) - 2020845..2021792 (-) 948 WP_230321698.1 MFS transporter -
  SGPB_RS09925 (SGPB_1953) - 2022385..2022687 (-) 303 WP_230321699.1 hypothetical protein -
  SGPB_RS11555 (SGPB_1955) - 2022988..2023164 (-) 177 WP_230321700.1 hypothetical protein -
  SGPB_RS09935 (SGPB_1956) - 2023311..2024162 (+) 852 WP_013852329.1 helix-turn-helix domain-containing protein -
  SGPB_RS09940 (SGPB_1957) ruvA 2024242..2024835 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45426.82 Da        Isoelectric Point: 5.1768

>NTDB_id=41097 SGPB_RS09915 WP_013852328.1 2019216..2020475(-) (cinA) [Streptococcus pasteurianus ATCC 43144]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNGVTYVVLPGPPSELKPM
VLDSLVPLLSGDHKQLYSRVLRFFGIGESQLVTVLADLIDNQTDPTIAPYAKTGEVTLRLSTKADDVTSAKAKLDALEHK
ILAKKTLNSIPLEQLLYGYGDDNSMARVVFDLLKEKHKTITAAESLTAGLFQSSITDFSGSSAVFNGGFVTYSIEEKSKM
LHIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=41097 SGPB_RS09915 WP_013852328.1 2019216..2020475(-) (cinA) [Streptococcus pasteurianus ATCC 43144]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAGTTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGGCGTGACCTACGTTGTTCTCCCTGGACCACCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTGCCTTTGTTGTCTGGAGACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTCTTGGCAGATTTGATTGATAACCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGACGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTACTTTATGGCTACGGTGATGATAACAGTATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACTATTACAGCTGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCACTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTAAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTCATTGGTATTGCGACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5X3T6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.182

99.523

0.718
  cinA Streptococcus mitis SK321

71.292

99.761

0.711
  cinA Streptococcus mitis NCTC 12261

71.053

99.761

0.709
  cinA Streptococcus pneumoniae Rx1

70.335

99.761

0.702
  cinA Streptococcus pneumoniae TIGR4

70.335

99.761

0.702
  cinA Streptococcus pneumoniae R6

70.335

99.761

0.702
  cinA Streptococcus pneumoniae D39

70.096

99.761

0.699
  cinA Streptococcus suis isolate S10

54.087

99.284

0.537
  cinA Bacillus subtilis subsp. subtilis str. 168

45.972

100

0.463

Multiple sequence alignment