Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   GPZ88_RS10350 Genome accession   NZ_CP046919
Coordinates   640943..641773 (-) Length   276 a.a.
NCBI ID   WP_240915108.1    Uniprot ID   -
Organism   Streptococcus ruminicola strain CNU_G2     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 635943..646773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS03285 (GPZ88_03260) comE/comE2 636800..637534 (-) 735 WP_052071091.1 LytR/AlgR family response regulator transcription factor Regulator
  GPZ88_RS03290 (GPZ88_03265) comD/comD3 638195..639571 (-) 1377 WP_240915106.1 sensor histidine kinase Regulator
  GPZ88_RS03295 (GPZ88_03270) comD/comD3 639568..640650 (-) 1083 WP_240915107.1 sensor histidine kinase Regulator
  GPZ88_RS10350 comD/comD2 640943..641773 (-) 831 WP_240915108.1 sensor histidine kinase Regulator
  GPZ88_RS03305 (GPZ88_03280) - 642677..642970 (-) 294 WP_074626913.1 bacteriocin immunity protein -
  GPZ88_RS03310 (GPZ88_03285) - 642998..643303 (-) 306 WP_158914537.1 bacteriocin immunity protein -
  GPZ88_RS03315 (GPZ88_03290) - 643316..643465 (-) 150 WP_039696228.1 hypothetical protein -
  GPZ88_RS03320 (GPZ88_03295) comC/comC1 643728..643880 (+) 153 WP_158914538.1 hypothetical protein Regulator
  GPZ88_RS03325 (GPZ88_03300) comD/comD1 643903..645228 (-) 1326 WP_166043386.1 sensor histidine kinase Regulator
  GPZ88_RS03330 (GPZ88_03305) comE/comE1 645233..645964 (-) 732 WP_166043387.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 276 a.a.        Molecular weight: 31324.58 Da        Isoelectric Point: 4.6365

>NTDB_id=409461 GPZ88_RS10350 WP_240915108.1 640943..641773(-) (comD/comD2) [Streptococcus ruminicola strain CNU_G2]
MDAVAIVKPFHNADNDVIRGIVAFIYLILLFIFLFYLNFRHGQEQKNELLRNQEMELAALENYSKHVESLYQEVRSFRHD
YANVLMTLKMGIDQGNLDDIKKIYDEITADSTKLVKNNKFDLTRLANITDSGVKSLVSAKFLQAENQGIAISLEVAEEMG
TPKIPLISYIRILSILFDNAIEGALESAEPKISVANFYQDGDFVFMIENSSKEKSVDLTKIFERGYSTKGDNRGIGLATL
MDFQDDYENLSVETHSSDCTFTQVVRIYDREGKNIG

Nucleotide


Download         Length: 831 bp        

>NTDB_id=409461 GPZ88_RS10350 WP_240915108.1 640943..641773(-) (comD/comD2) [Streptococcus ruminicola strain CNU_G2]
ATGGATGCTGTTGCTATTGTAAAACCTTTTCATAATGCTGATAACGATGTAATAAGGGGAATTGTTGCTTTCATTTATCT
CATCCTTCTTTTTATCTTCCTCTTTTACCTCAATTTTCGTCATGGGCAGGAGCAGAAAAATGAATTGCTTCGCAATCAGG
AGATGGAATTGGCGGCCTTGGAAAATTATAGCAAACACGTGGAAAGCCTTTATCAAGAAGTGCGCAGTTTCAGGCATGAC
TACGCTAATGTTTTGATGACCTTAAAAATGGGGATTGATCAAGGCAATCTTGATGACATCAAGAAAATTTACGACGAAAT
CACAGCCGATTCAACGAAACTGGTCAAGAATAATAAGTTTGACTTGACTCGCTTGGCTAACATCACAGACAGCGGCGTCA
AAAGCCTGGTGTCAGCCAAATTCTTGCAAGCTGAAAATCAAGGGATTGCGATTAGCTTGGAAGTTGCTGAAGAAATGGGA
ACTCCAAAGATTCCATTGATTTCCTATATCCGAATTTTGTCGATTCTGTTTGATAATGCCATAGAAGGAGCTTTGGAATC
TGCGGAGCCAAAAATCTCAGTCGCTAATTTTTACCAAGATGGTGACTTTGTTTTCATGATTGAAAATTCAAGTAAGGAAA
AATCGGTGGATTTAACTAAGATTTTTGAGCGTGGCTACTCAACCAAAGGAGATAATCGCGGAATTGGTCTGGCAACGCTG
ATGGATTTCCAAGATGACTACGAAAATCTGTCGGTTGAAACCCACAGTTCAGATTGCACATTCACACAAGTAGTGAGAAT
ATACGATAGAGAAGGTAAAAATATTGGATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(170-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus equinus JB1

91.575

98.913

0.906
  comD/comD3 Streptococcus equinus JB1

85.609

98.188

0.841
  comD/comD1 Streptococcus equinus JB1

47.679

85.87

0.409
  comD/blpH Streptococcus mutans UA159

41.365

90.217

0.373

Multiple sequence alignment