Detailed information NTG0409408

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: GPZ88_RS03330
• Genome accession: NZ_CP046919
• Coordinates: 645233..645964 (-)
• Length: 243 a.a.
• NCBI ID: WP_166043387.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G2
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 640233..650964

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPZ88_RS10350	comD/comD2	640943..641773 (-)	831	WP_240915108.1	sensor histidine kinase	Regulator
GPZ88_RS03305 (GPZ88_03280)	-	642677..642970 (-)	294	WP_074626913.1	bacteriocin immunity protein	-
GPZ88_RS03310 (GPZ88_03285)	-	642998..643303 (-)	306	WP_158914537.1	bacteriocin immunity protein	-
GPZ88_RS03315 (GPZ88_03290)	-	643316..643465 (-)	150	WP_039696228.1	hypothetical protein	-
GPZ88_RS03320 (GPZ88_03295)	comC/comC1	643728..643880 (+)	153	WP_158914538.1	hypothetical protein	Regulator
GPZ88_RS03325 (GPZ88_03300)	comD/comD1	643903..645228 (-)	1326	WP_166043386.1	sensor histidine kinase	Regulator
GPZ88_RS03330 (GPZ88_03305)	comE/comE1	645233..645964 (-)	732	WP_166043387.1	response regulator transcription factor	Regulator
GPZ88_RS03335 (GPZ88_03310)	-	646732..647421 (-)	690	WP_074626894.1	CPBP family intramembrane glutamic endopeptidase	-
GPZ88_RS03340 (GPZ88_03315)	-	647486..647638 (-)	153	WP_159428313.1	hypothetical protein	-
GPZ88_RS03345 (GPZ88_03320)	-	647652..647792 (-)	141	WP_159428314.1	bacteriocin class II family protein	-
GPZ88_RS03350 (GPZ88_03325)	-	647815..648423 (-)	609	WP_074626895.1	CPBP family intramembrane glutamic endopeptidase	-
GPZ88_RS03355 (GPZ88_03330)	-	648398..648562 (-)	165	WP_159428316.1	lactococcin G-beta/enterocin 1071B family bacteriocin	-
GPZ88_RS03360 (GPZ88_03335)	-	648565..648720 (-)	156	WP_107374736.1	bacteriocin class II family protein	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28194.11 Da
• Isoelectric Point: 6.0479

>NTDB_id=409408 GPZ88_RS03330 WP_166043387.1 645233..645964(-) (comE/comE1) [Streptococcus ruminicola strain CNU_G2]
MLDIFILEDNITQQFRIERQIETIMERNHWEYQRLEAFAASKDIIKKADGQGNYQVFFLDLEIKGDEKQGLDVARSIREK
DPTAIIVFVTTHSEFMLLTYQSLVGAIDFIDKNMNDEAFGGRIELCLKEALKYQTGSFGENSYLFETAKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDKRLLKCHRSFVINVNNVTEFDKSTRTAYFENGSYCQVSRDKVKKLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=409408 GPZ88_RS03330 WP_166043387.1 645233..645964(-) (comE/comE1) [Streptococcus ruminicola strain CNU_G2]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACGCAACAATTTCGAATCGAACGTCAGATTGAGACGATTATGGAAAG
GAACCACTGGGAGTATCAGCGTTTAGAGGCTTTTGCGGCATCTAAGGATATTATAAAAAAGGCAGATGGGCAGGGAAATT
ACCAGGTTTTCTTTCTTGATTTAGAAATCAAAGGGGATGAAAAGCAAGGCTTAGATGTTGCTAGATCTATTCGTGAAAAA
GATCCGACAGCCATTATCGTCTTTGTGACAACCCATTCTGAGTTTATGCTTCTAACTTATCAATCACTAGTTGGTGCGAT
TGATTTTATTGATAAAAATATGAATGATGAAGCCTTTGGAGGGCGCATTGAATTGTGCTTGAAAGAGGCATTGAAATATC
AAACTGGTAGTTTTGGCGAGAATTCTTACCTGTTTGAAACAGCAAAAGCAAGAATCCGCGTGGCTTATGATGATATTTTA
TATTTTGAAACATCACCAACTGTGCACCGTGTGATTTTACACACTAAAACAGGTCAAACAGAGTTTTATGGCACAATTGC
TGAGGTGGCTAAATCAGATAAACGTTTGTTGAAATGTCACCGCTCATTCGTGATTAATGTTAATAATGTCACTGAATTTG
ATAAAAGCACCCGAACAGCTTATTTCGAAAACGGCTCTTACTGCCAAGTCTCAAGAGACAAAGTCAAAAAACTGATGGCA
GAAATGAGGTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	99.588	100	0.996
comE/blpR	Streptococcus mutans UA159	46.473	99.177	0.461
comE/comE2	Streptococcus equinus JB1	45.041	99.588	0.449