Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   GPZ88_RS03965 Genome accession   NZ_CP046919
Coordinates   777432..778691 (-) Length   419 a.a.
NCBI ID   WP_166043513.1    Uniprot ID   A0A6G8HZL1
Organism   Streptococcus ruminicola strain CNU_G2     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 772432..783691
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPZ88_RS03935 (GPZ88_03895) - 772491..774065 (-) 1575 WP_166043511.1 DUF2079 domain-containing protein -
  GPZ88_RS10400 - 774108..774236 (-) 129 WP_267887989.1 hypothetical protein -
  GPZ88_RS03940 (GPZ88_03900) - 774352..774669 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  GPZ88_RS03945 (GPZ88_03905) ruvX 774702..775121 (-) 420 WP_020917593.1 Holliday junction resolvase RuvX -
  GPZ88_RS03950 (GPZ88_03910) - 775118..775387 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  GPZ88_RS03955 (GPZ88_03915) spx 775635..776033 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  GPZ88_RS03960 (GPZ88_03920) recA 776231..777385 (-) 1155 WP_039696214.1 recombinase RecA Machinery gene
  GPZ88_RS03965 (GPZ88_03925) cinA 777432..778691 (-) 1260 WP_166043513.1 competence/damage-inducible protein A Machinery gene
  GPZ88_RS03970 (GPZ88_03930) - 778820..779998 (-) 1179 WP_166043515.1 MFS transporter -
  GPZ88_RS03975 (GPZ88_03935) - 780203..780754 (-) 552 WP_166043517.1 DNA-3-methyladenine glycosylase I -
  GPZ88_RS03980 (GPZ88_03940) ruvA 780784..781377 (-) 594 WP_074869549.1 Holliday junction branch migration protein RuvA -
  GPZ88_RS03985 (GPZ88_03945) mutL 781378..783318 (-) 1941 WP_039696139.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45756.07 Da        Isoelectric Point: 4.9842

>NTDB_id=409419 GPZ88_RS03965 WP_166043513.1 777432..778691(-) (cinA) [Streptococcus ruminicola strain CNU_G2]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIDLASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLDEFFATRPQFTRTANNERQAQLIEGSTPLQNSTGLAVGGVIEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIDNQTDPTIAPYAKTGEVTLRLSTKADDIESANEKLDQLEQK
ILSKKTLNSIPLENLLYGYGDDNSMARVVFDLLKKKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKAKM
LQIPLKDLQEHGVVSHFTAEKMAEQSRKLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVLIGGRSRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=409419 GPZ88_RS03965 WP_166043513.1 777432..778691(-) (cinA) [Streptococcus ruminicola strain CNU_G2]
ATGAAAGCTGAGATTATCGCTGTAGGAACAGAGATTTTAACAGGACAAATCACAAATACCAATGCGCAATTTTTATCTGA
AGAATTTGCCAAGTTAGGGATTGATGTCTTTTTCCAAACGGCAGTTGGGGACAATGAAGAACGTCTTTTGTCTATCATTG
ATTTGGCAAGTAAGCGTAGCGATTTAGTTGTTCTCTGTGGTGGTTTAGGACCAACTGAGGATGATTTGACAAAGCAAACC
TTAGCAAAATATTTAGGGCGTAACCTGGTCTTTGACGAACAGGCAAGTAAACGTCTAGATGAGTTCTTTGCGACACGTCC
TCAATTTACAAGAACAGCTAACAATGAACGCCAAGCTCAACTAATTGAAGGTTCAACTCCTTTGCAAAATAGCACTGGTT
TGGCTGTAGGTGGAGTGATTGAAGTTGACGGCGTCACTTATGTTGTTCTTCCTGGCCCACCAAGTGAGCTTAAGCCCATG
GTCTGGGATTATTTAGTGCCTTTGTTATCTAGCGACCATAAGCAACTTTATTCACGTGTTTTGCGTTTCTTTGGCATTGG
AGAAAGCCAACTGGTAACTGTTTTATCAGATTTGATTGACAACCAAACCGATCCAACCATTGCGCCATATGCTAAGACAG
GTGAAGTAACGCTGCGTTTGTCAACGAAAGCAGACGACATTGAATCAGCTAATGAAAAACTAGACCAGCTAGAGCAAAAA
ATTCTTTCTAAGAAGACTTTAAATAGCATTCCACTTGAGAATTTGCTTTATGGTTACGGTGATGACAATAGTATGGCGCG
TGTTGTTTTTGATTTGCTTAAGAAAAAACACAAGACTATCACAGCTGCAGAAAGTTTAACAGCAGGGCTATTTCAATCAA
GTATTGCAGACTTCTCAGGCTCTTCAGCAGTTTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAGGCAAAAATG
CTTCAAATCCCTTTAAAAGATTTACAAGAACATGGGGTTGTGAGTCATTTTACAGCTGAAAAAATGGCTGAGCAATCTCG
CAAGTTAACAGATGCTGATTTTGGGATTGGATTGACAGGAGTTGCAGGACCAGATAGCTTAGAAGGTCACCCAGCGGGAA
CAGTTTTCATTGGTATTGCTACTAGAGAAAAAGTTCATTCTATTCGTGTTCTCATAGGTGGACGAAGCCGTTCAGATGTG
CGTCATATTGCATGTTTGTATGCATTTAACTTAGTACGTCAAGCTTTATTACAAGATTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6G8HZL1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

72.315

100

0.723
  cinA Streptococcus mutans UA159

72.422

99.523

0.721
  cinA Streptococcus mitis NCTC 12261

71.36

100

0.714
  cinA Streptococcus pneumoniae Rx1

70.167

100

0.702
  cinA Streptococcus pneumoniae TIGR4

70.167

100

0.702
  cinA Streptococcus pneumoniae R6

70.167

100

0.702
  cinA Streptococcus pneumoniae D39

69.928

100

0.699
  cinA Streptococcus suis isolate S10

55.048

99.284

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

45.735

100

0.461

Multiple sequence alignment