Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   GPY18_RS17395 Genome accession   NZ_CP046800
Coordinates   2212740..2213966 (-) Length   408 a.a.
NCBI ID   WP_020332199.1    Uniprot ID   S7J7L5
Organism   Vibrio fluvialis strain 2012V-1235     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2207740..2218966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPY18_RS17370 parC 2207859..2210132 (+) 2274 WP_047459105.1 DNA topoisomerase IV subunit A -
  GPY18_RS17375 yacG 2210183..2210380 (-) 198 WP_020332195.1 DNA gyrase inhibitor YacG -
  GPY18_RS17380 zapD 2210435..2211175 (-) 741 WP_020332196.1 cell division protein ZapD -
  GPY18_RS17385 coaE 2211208..2211816 (-) 609 WP_158147130.1 dephospho-CoA kinase -
  GPY18_RS17390 pilD 2211819..2212688 (-) 870 WP_020332198.1 A24 family peptidase Machinery gene
  GPY18_RS17395 pilC 2212740..2213966 (-) 1227 WP_020332199.1 type II secretion system F family protein Machinery gene
  GPY18_RS17400 pilB 2214002..2215690 (-) 1689 WP_158147131.1 type IV-A pilus assembly ATPase PilB Machinery gene
  GPY18_RS17405 pilA 2215700..2216119 (-) 420 WP_047459095.1 pilin Machinery gene
  GPY18_RS17410 nadC 2216351..2217238 (-) 888 WP_104966496.1 carboxylating nicotinate-nucleotide diphosphorylase -
  GPY18_RS17415 ampD 2217391..2217942 (+) 552 WP_158147132.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  GPY18_RS17420 fldB 2217947..2218468 (-) 522 WP_020430452.1 flavodoxin FldB -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44670.91 Da        Isoelectric Point: 10.5318

>NTDB_id=408025 GPY18_RS17395 WP_020332199.1 2212740..2213966(-) (pilC) [Vibrio fluvialis strain 2012V-1235]
MKPTKGPELKNYRWKGVNSTGKKVAGQTLAISEIEVRDKLKEQHIQVKKIKKGSVSVLTRLTNRVKTKDITILTRQLATM
LTTGVPIVQALKLVGDNHRKAEMKSILAQITKGVEAGTPISKAMRTASTHFDALYVDLIQTGEQSGNLAEVFERLATYRE
KSEQLRAKVIKALIYPSMVILVALGVSYLMLTMVIPEFESMFKGFGAELPWFTQQILKLSHGVQAYSAGAFIASLGLVFG
IKAARKKSFVVRLKTSQLSLRFPIIGGVLAKAAIAKFSRTLATSFSAGIPILASLKTTAKTAGNVHFETAIQDVHRHTAA
GMPMYIAMRNTQAFPEMVLQMVMIGEESGKLDDMLNKVATIYEFEVDNTVDNLGKILEPLIIVFLGIVVGGLVVAMYLPI
FNLMSVLG

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=408025 GPY18_RS17395 WP_020332199.1 2212740..2213966(-) (pilC) [Vibrio fluvialis strain 2012V-1235]
ATGAAACCGACCAAAGGCCCTGAGTTAAAAAACTATCGCTGGAAAGGCGTCAACAGCACTGGCAAGAAAGTCGCGGGACA
GACACTGGCTATCAGTGAAATAGAAGTCCGCGACAAACTGAAAGAACAGCACATTCAGGTTAAGAAGATCAAAAAAGGCA
GCGTGTCAGTTCTGACTCGTCTCACCAATCGGGTCAAAACTAAAGACATCACCATCCTAACCCGCCAGCTTGCCACCATG
CTGACCACCGGAGTGCCAATTGTGCAGGCACTTAAATTGGTCGGCGATAATCATCGTAAAGCCGAGATGAAATCGATTCT
GGCGCAAATTACCAAAGGCGTCGAAGCCGGTACGCCGATTTCCAAAGCGATGCGCACTGCCAGCACTCACTTTGACGCGT
TGTACGTCGACTTAATTCAGACTGGCGAGCAGTCCGGCAATCTTGCCGAAGTCTTTGAACGCCTTGCCACCTATCGGGAA
AAAAGTGAGCAACTGCGCGCGAAAGTAATCAAAGCGCTGATCTATCCCAGCATGGTCATTCTGGTGGCACTCGGCGTCTC
CTATTTGATGCTGACGATGGTCATTCCAGAGTTCGAAAGTATGTTCAAGGGTTTTGGGGCTGAACTGCCTTGGTTTACTC
AGCAGATCCTCAAGTTATCGCATGGGGTACAAGCCTACAGTGCGGGGGCGTTCATCGCGTCATTGGGCTTGGTGTTTGGC
ATCAAAGCGGCGCGGAAAAAATCCTTCGTCGTCCGTCTTAAAACCAGCCAGCTCAGCCTGCGTTTTCCCATCATTGGGGG
TGTGCTTGCCAAAGCCGCAATTGCCAAATTCAGCCGCACTCTGGCGACCAGCTTCAGTGCGGGAATTCCGATACTCGCCA
GCCTCAAAACCACCGCTAAAACGGCAGGTAACGTGCATTTTGAAACCGCCATTCAGGATGTTCACCGCCATACGGCAGCA
GGGATGCCGATGTATATTGCAATGCGCAACACACAAGCCTTTCCGGAAATGGTGTTGCAAATGGTGATGATCGGCGAGGA
GTCCGGCAAGCTCGACGACATGCTCAATAAAGTCGCCACCATCTATGAGTTTGAAGTCGACAACACCGTCGACAATCTGG
GCAAAATTCTTGAACCGCTGATTATCGTATTTTTGGGCATTGTGGTCGGTGGATTGGTGGTGGCGATGTACCTGCCAATC
TTTAACTTAATGAGTGTATTAGGTTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(74-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S7J7L5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

87.01

100

0.87
  pilC Vibrio campbellii strain DS40M4

73.105

100

0.733
  pilC Acinetobacter baumannii D1279779

41.667

100

0.417
  pilC Legionella pneumophila strain ERS1305867

41.353

97.794

0.404
  pilC Acinetobacter baylyi ADP1

41.31

97.304

0.402
  pilC Pseudomonas stutzeri DSM 10701

40.152

97.059

0.39
  pilG Neisseria gonorrhoeae MS11

39.599

97.794

0.387
  pilG Neisseria meningitidis 44/76-A

39.098

97.794

0.382

Multiple sequence alignment