Detailed information NTG0406199

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GO995_RS09010
• Genome accession: NZ_CP046624
• Coordinates: 1811466..1812200 (-)
• Length: 244 a.a.
• NCBI ID: WP_157629451.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G3
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1806466..1817200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO995_RS08990 (GO995_08990)	-	1806939..1807811 (-)	873	WP_157629447.1	ABC transporter ATP-binding protein	-
GO995_RS08995 (GO995_08995)	-	1807839..1808585 (-)	747	WP_157629448.1	hypothetical protein	-
GO995_RS09000 (GO995_09000)	-	1808730..1810088 (-)	1359	WP_157629449.1	sensor histidine kinase	-
GO995_RS09005 (GO995_09005)	-	1810092..1811462 (-)	1371	WP_157629450.1	sensor histidine kinase	-
GO995_RS09010 (GO995_09010)	comE/blpR	1811466..1812200 (-)	735	WP_157629451.1	response regulator transcription factor	Regulator
GO995_RS09015 (GO995_09015)	-	1812210..1812542 (-)	333	WP_157629452.1	LytR/AlgR family response regulator transcription factor	-
GO995_RS09020 (GO995_09020)	-	1812729..1813088 (+)	360	WP_157629453.1	response regulator	-
GO995_RS09025 (GO995_09025)	clpC	1813146..1815587 (-)	2442	WP_157629454.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GO995_RS09030 (GO995_09030)	-	1815584..1816045 (-)	462	WP_039696152.1	CtsR family transcriptional regulator	-
GO995_RS09035 (GO995_09035)	-	1816303..1816767 (+)	465	WP_074560991.1	COG2426 family protein	-

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28283.16 Da
• Isoelectric Point: 5.6161

>NTDB_id=406199 GO995_RS09010 WP_157629451.1 1811466..1812200(-) (comE/blpR) [Streptococcus ruminicola strain CNU_G3]
MLNIFVLEDDFFQQSRLEQAINRCVKENQLKYRQLEIFGKPQQLLDAIKEQGNHQFFFLDIEIKGDEKKGMEIAREIRAK
DPNAVIVFVTTHSEFMPVTYKYRVAALDFIDKGLADSDFYDAVSSVLVYAFENVGTTVASDAFVFRNEHSHVQVPFSDIL
YFETSSTIHKVVLTTKTGHMEFYGKVSDIAKADERLYQSHRAYVVNPENVIKIDRTNHIVYFEDDESCFVSRLKLKGLIE
RVEK

Nucleotide

• Length: 735 bp

>NTDB_id=406199 GO995_RS09010 WP_157629451.1 1811466..1812200(-) (comE/blpR) [Streptococcus ruminicola strain CNU_G3]
ATGCTAAATATCTTTGTGTTAGAGGATGATTTTTTCCAACAATCACGTTTGGAACAAGCTATTAATCGTTGTGTGAAAGA
AAATCAACTGAAATACCGTCAGTTGGAGATTTTTGGCAAACCTCAGCAGCTTTTAGATGCAATTAAGGAACAAGGAAATC
ATCAATTTTTCTTTTTGGATATTGAAATAAAAGGTGACGAGAAAAAAGGAATGGAGATAGCGCGTGAGATTCGTGCAAAA
GACCCTAATGCAGTGATTGTTTTTGTGACAACTCATTCTGAGTTTATGCCAGTGACTTATAAATACCGTGTAGCTGCTCT
TGATTTTATTGATAAGGGGCTAGCAGATAGTGATTTTTACGATGCGGTATCTTCTGTTTTGGTATACGCTTTTGAAAATG
TTGGTACAACTGTAGCCAGTGATGCTTTTGTTTTTAGAAATGAGCACTCTCACGTTCAAGTCCCATTTTCAGATATTCTA
TATTTTGAAACGTCTTCGACTATCCACAAAGTTGTTTTAACCACAAAAACAGGTCACATGGAATTTTATGGTAAAGTTTC
AGATATTGCAAAGGCAGATGAACGACTTTATCAAAGTCATCGTGCCTATGTCGTTAATCCAGAAAATGTCATTAAAATTG
ATCGCACTAACCATATTGTCTATTTTGAAGATGATGAATCGTGCTTTGTGTCACGTCTGAAACTAAAAGGATTAATCGAA
AGAGTGGAGAAATAG

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-241)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	55.649	97.951	0.545
comE/comE1	Streptococcus equinus JB1	46.025	97.951	0.451
comE/comE2	Streptococcus equinus JB1	41.975	99.59	0.418
comE	Streptococcus infantis strain Atu-4	36.4	100	0.373
comE	Streptococcus pneumoniae Rx1	36.4	100	0.373
comE	Streptococcus pneumoniae D39	36.4	100	0.373
comE	Streptococcus pneumoniae R6	36.4	100	0.373
comE	Streptococcus pneumoniae TIGR4	36.4	100	0.373
comE	Streptococcus mitis SK321	36.4	100	0.373
comE	Streptococcus mitis NCTC 12261	36.4	100	0.373