Detailed information NTG0406200

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GO995_RS09025
• Genome accession: NZ_CP046624
• Coordinates: 1813146..1815587 (-)
• Length: 813 a.a.
• NCBI ID: WP_157629454.1
• Uniprot ID: -
• Organism: Streptococcus ruminicola strain CNU_G3
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1808146..1820587

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GO995_RS09000 (GO995_09000)	-	1808730..1810088 (-)	1359	WP_157629449.1	sensor histidine kinase	-
GO995_RS09005 (GO995_09005)	-	1810092..1811462 (-)	1371	WP_157629450.1	sensor histidine kinase	-
GO995_RS09010 (GO995_09010)	comE/blpR	1811466..1812200 (-)	735	WP_157629451.1	response regulator transcription factor	Regulator
GO995_RS09015 (GO995_09015)	-	1812210..1812542 (-)	333	WP_157629452.1	LytR/AlgR family response regulator transcription factor	-
GO995_RS09020 (GO995_09020)	-	1812729..1813088 (+)	360	WP_157629453.1	response regulator	-
GO995_RS09025 (GO995_09025)	clpC	1813146..1815587 (-)	2442	WP_157629454.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GO995_RS09030 (GO995_09030)	-	1815584..1816045 (-)	462	WP_039696152.1	CtsR family transcriptional regulator	-
GO995_RS09035 (GO995_09035)	-	1816303..1816767 (+)	465	WP_074560991.1	COG2426 family protein	-
GO995_RS09040 (GO995_09040)	tsf	1817153..1818190 (-)	1038	WP_157629455.1	translation elongation factor Ts	-
GO995_RS09045 (GO995_09045)	rpsB	1818299..1819066 (-)	768	WP_074564586.1	30S ribosomal protein S2	-
GO995_RS09055 (GO995_09055)	-	1819586..1820539 (+)	954	WP_157629456.1	S66 family peptidase	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90033.62 Da
• Isoelectric Point: 6.5806

>NTDB_id=406200 GO995_RS09025 WP_157629454.1 1813146..1815587(-) (clpC) [Streptococcus ruminicola strain CNU_G3]
MSEYSMKMQEVFSIAQYQAARFESPYLESWHMLLAMVAVHDSVAGLTFAEYQNKIAYEEYEAAAVLALGKSPLADVKNVQ
FLEQSKALKDVLAFAESICKVTGSTEVGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDSARLLDLRKSLSRNAGFTKE
KIKAIHDLRKPKKATMGGAFSEMMKPQSTAGELSDFTRDLTELARQGKLEPVIGREKEVSRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGEIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEADGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHIEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYETFHNVTISDQ
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPAALTAADKAILEGDFKLATKLLKESRKKVTRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLTLEKELHKRVIGQDAAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGARDMAHDYDAMQKRIMEELKKAYRPEFINRIDEKVVFHH
LTQENMRDVVKIMVKPLIETLAEKDITLKFQPSALKYLAEAGYDPEMGARPLRRTLQDKVEDKLSELILAGNLASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=406200 GO995_RS09025 WP_157629454.1 1813146..1815587(-) (clpC) [Streptococcus ruminicola strain CNU_G3]
ATGAGTGAATATTCAATGAAAATGCAGGAGGTTTTCAGTATTGCCCAGTACCAAGCGGCGCGATTTGAAAGCCCATATTT
AGAAAGTTGGCATATGCTTTTAGCCATGGTAGCTGTTCATGATTCAGTGGCAGGGTTAACATTTGCTGAATACCAAAATA
AGATTGCTTACGAAGAGTACGAAGCGGCAGCTGTTTTGGCGCTCGGGAAATCACCTTTGGCAGATGTGAAAAATGTGCAG
TTCTTAGAACAATCTAAAGCCCTAAAAGACGTCTTAGCTTTTGCTGAGTCAATTTGCAAAGTGACTGGCAGCACCGAAGT
CGGAACAGAGCATGTCCTTTATGCTATGTTGTTGAATCTCGATTTGTTTGCGACACGTTTGTTAGAAGTTGCTGGATTCA
AAAATAAAGAAGATGGTGATTCAGCACGCTTGCTTGATTTGCGTAAATCATTGTCACGTAATGCTGGATTTACTAAAGAA
AAAATCAAAGCTATTCACGATCTTCGCAAACCCAAAAAAGCTACAATGGGCGGAGCTTTCTCAGAAATGATGAAACCTCA
GTCAACTGCGGGAGAATTATCAGACTTCACTCGTGATTTAACTGAATTAGCTCGTCAAGGAAAACTTGAGCCAGTTATCG
GACGTGAAAAAGAAGTCTCTCGCATGGTTCAAGTACTTAGCCGTAAGACTAAAAATAATCCTGTCTTGGTCGGTGAAGCA
GGGGTCGGTAAAACTGCCCTTGCTTATGGTCTAGCGCAGCGTATTGTCAATGGTGAAATTCCTTATGAACTCCAAGATAT
GCGTGTCTTAGAGCTTGATATGATGAGTGTTGTTGCGGGGACTCGTTTCCGTGGTGATTTCGAAGAACGCATGAACCAAA
TCATCTCAGACATTGAAGCTGATGGTCATATTATTTTATTTATCGATGAAGTCCACACTATCATGGGTTCTGGTTCAGGT
ATTGATAGTACTTTGGATGCTGCTAATATCTTAAAACCTGCTCTTGCACGTGGTACGCTTCACATGGTTGGTGCGACAAC
TCAAGAAGAATATCAAAAACATATCGAAAAAGATGCAGCTCTTTCACGTCGTTTTGCGAAAATTACGATTGAAGAACCAA
GTGTTGAAGATGCTTATCAAATTTTACTTGGGCTTAAGAAATCTTACGAAACTTTCCATAATGTGACGATTTCTGATCAA
GCTGTGTTGACGGCTGTTAAAGCTGCACACCGTTATTTGACAAGTAAAAATCTACCAGATTCAGCTATTGATTTGCTTGA
TGAAGCTAGTGCAACTGTTCAAGGTTTGGTTAAAAAAGAAGCCCCAGCAGCTCTTACAGCTGCAGATAAAGCTATTTTAG
AAGGTGATTTCAAATTAGCTACAAAATTGCTTAAAGAGTCACGTAAGAAAGTGACACGTAAACCAACAGCTGTGACTGAA
GATGATATCATGGCAACACTTAGTCGTCTGTCAGGTATTCCTGTTGAGAAAATGACACAAGCCGACAGCAAGAAATATTT
GACGCTTGAAAAAGAATTGCACAAACGTGTTATTGGTCAAGATGCTGCGATTTCTGCCATTAGCCGTGCTATTCGTCGAA
ATCAAGCTGGTATCCGCACAGGAAAACGTCCAATTGGTTCATTCATGTTCTTAGGACCTACTGGTGTTGGTAAGACTGAA
TTAGCTAAAGCTTTGGCTGAACTTCTCTTTGATGATGAATCAGCACTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCGGCGAGTCGTCTTAACGGAGCTCCTCCAGGATACGTTGGTTATGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GTAACAAACCTTATTCAGTCCTTCTTTTCGATGAAGTTGAAAAAGCTCATCCAGATATTTTCAACGTCCTTCTTCAAGTT
TTGGATGATGGTGTGTTGACAGATAGTCGTGGTCGTAAAGTTGACTTCTCAAATACTATTATTATCATGACGTCAAACCT
TGGTGCGACTGCCCTTCGTGATGATAAAACTGTTGGATTTGGTGCGCGTGATATGGCTCATGATTATGATGCTATGCAAA
AACGTATCATGGAAGAACTTAAGAAAGCTTATCGTCCAGAATTTATCAACCGTATTGATGAAAAGGTTGTCTTCCACCAC
TTGACACAAGAAAATATGCGTGACGTGGTTAAAATCATGGTTAAACCATTGATTGAAACCTTAGCTGAAAAAGATATTAC
GCTTAAATTCCAACCATCAGCACTTAAATATCTTGCTGAGGCTGGATATGACCCAGAAATGGGAGCTCGTCCACTTCGTC
GTACTCTCCAAGATAAAGTTGAAGATAAATTATCAGAGCTTATCCTAGCAGGCAACCTAGCAAGTGGAAATACCCTTAAA
ATTGGTGTTTCTAAAGGACAACTCAAATTTGATATTGCATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-134)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (374-454)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	77.463	99.877	0.774
clpC	Streptococcus thermophilus LMG 18311	73.988	100	0.742
clpC	Streptococcus thermophilus LMD-9	73.865	100	0.74
clpC	Streptococcus pneumoniae TIGR4	67.488	99.877	0.674
clpC	Streptococcus pneumoniae Rx1	67.488	99.877	0.674
clpC	Streptococcus pneumoniae D39	67.488	99.877	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.82	100	0.512
clpC	Bacillus subtilis subsp. subtilis str. 168	43.923	100	0.449