Detailed information NTG0040232

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SOR_RS09705
• Genome accession: NC_015291
• Coordinates: 1956466..1957662 (+)
• Length: 398 a.a.
• NCBI ID: WP_000681803.1
• Uniprot ID: -
• Organism: Streptococcus oralis Uo5
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1951466..1962662

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOR_RS09665 (SOR_1981)	-	1952526..1953068 (+)	543	WP_000665079.1	TetR/AcrR family transcriptional regulator	-
SOR_RS09680 (SOR_1984)	comE	1953311..1954057 (-)	747	WP_000866078.1	competence system response regulator transcription factor ComE	Regulator
SOR_RS09685 (SOR_1985)	comD	1954054..1955373 (-)	1320	WP_000362884.1	competence system sensor histidine kinase ComD	Regulator
SOR_RS09690 (SOR_1986)	comC/comC2	1955394..1955519 (-)	126	WP_000799678.1	competence-stimulating peptide ComC	Regulator
SOR_RS09700 (SOR_1989)	rlmH	1955801..1956280 (-)	480	WP_000694219.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SOR_RS09705 (SOR_1990)	htrA	1956466..1957662 (+)	1197	WP_000681803.1	S1C family serine protease	Regulator
SOR_RS09710 (SOR_1991)	spo0J	1957720..1958478 (+)	759	WP_000410359.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41985.76 Da
• Isoelectric Point: 6.6581

>NTDB_id=40232 SOR_RS09705 WP_000681803.1 1956466..1957662(+) (htrA) [Streptococcus oralis Uo5]
MKHLQKFYKKGVKVLAIILIGFLSGALGSFVTLQLYQKQGNQATNNNSGTVTQTSYKNENSTTQAVNKVKDAVVSIITYS
SSSSRQSSVFNGDETNSDSDNQQIASEGSGVIYKKDDKDAYLVTNTHVINGASKVDIRLADGTKVPGEIVGSDTFSDIAV
VKISSEKVTTVAEFGDSSQLSVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSG
GPLVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESNGKVTRPALGIQMVNLSNVGASDLRKLNIPSSL
TSGVVVRSVQNNMPANGHLQKYDVITKVDDKEIASSTDLQHALYNHAIGDTIKVTYYRNGKEETTSIKLDKNSGDLES

Nucleotide

• Length: 1197 bp

>NTDB_id=40232 SOR_RS09705 WP_000681803.1 1956466..1957662(+) (htrA) [Streptococcus oralis Uo5]
ATGAAACACTTACAAAAATTTTACAAAAAAGGAGTTAAAGTTCTTGCAATCATTCTAATAGGATTTTTAAGTGGTGCCTT
AGGAAGTTTCGTAACATTACAACTTTATCAAAAACAAGGAAATCAAGCTACGAATAATAATTCTGGCACTGTCACTCAAA
CATCATATAAGAATGAAAATTCAACCACTCAAGCAGTAAATAAAGTTAAGGATGCTGTTGTCTCAATCATTACTTATTCT
TCTTCTAGCAGTAGACAAAGTAGTGTATTTAATGGTGATGAAACTAATTCTGATTCAGACAATCAACAAATCGCAAGTGA
GGGATCAGGTGTTATCTATAAAAAAGATGATAAAGATGCCTATCTTGTAACTAATACTCACGTTATCAATGGAGCTTCAA
AAGTTGATATTCGCTTGGCAGATGGTACCAAGGTTCCTGGTGAAATTGTCGGATCTGATACTTTCTCTGATATTGCTGTC
GTTAAAATTTCTTCAGAAAAAGTTACAACAGTAGCAGAATTTGGGGATTCAAGCCAACTTAGTGTTGGAGAAACAGCGAT
TGCTATTGGTAGTCCTCTAGGTTCAGAATATGCTAATACAGTTACACAGGGAATCATCTCAAGTCTTAATCGAAATGTTT
CTCTAAAATCTGAAGATGGTCAAGCTATTTCAACAAAAGCCATTCAAACAGATACGGCTATTAACCCTGGTAACTCTGGT
GGTCCACTTGTAAACATTCAAGGACAAGTAATTGGTATTACATCAAGTAAAATTGCAAGTAATGGTGGAACATCTGTAGA
AGGTCTTGGTTTTGCAATTCCTTCAAACGATGCACAAAATATCATTAAACAGCTTGAAAGTAATGGTAAAGTGACTCGTC
CAGCTCTTGGAATTCAAATGGTCAATCTGTCAAATGTTGGAGCTAGTGATCTTAGAAAACTTAACATTCCAAGTAGCCTC
ACTTCAGGTGTAGTTGTTCGATCTGTTCAAAACAATATGCCAGCAAATGGACATCTTCAAAAATACGATGTCATTACCAA
AGTTGACGACAAAGAGATTGCTTCATCAACAGACCTACAACACGCTCTTTACAATCATGCTATCGGAGATACTATCAAAG
TAACCTACTACCGTAATGGTAAGGAGGAAACAACCTCAATTAAACTAGATAAGAATTCTGGTGATTTAGAGTCTTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (210-393)

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

• PDZ domain (PDZ_2) (294-389)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	83.668	100	0.837
htrA	Streptococcus pneumoniae Rx1	82.915	100	0.829
htrA	Streptococcus pneumoniae D39	82.915	100	0.829
htrA	Streptococcus pneumoniae R6	82.915	100	0.829
htrA	Streptococcus pneumoniae TIGR4	82.915	100	0.829
htrA	Streptococcus gordonii str. Challis substr. CH1	66.915	100	0.676
htrA	Streptococcus mutans UA159	54.822	98.995	0.543