Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD   Type   Regulator
Locus tag   SOR_RS09685 Genome accession   NC_015291
Coordinates   1954054..1955373 (-) Length   439 a.a.
NCBI ID   WP_000362884.1    Uniprot ID   A0A1X1GXK6
Organism   Streptococcus oralis Uo5     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1949054..1960373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS09660 (SOR_1980) - 1949743..1952397 (-) 2655 WP_000472071.1 YhgE/Pip domain-containing protein -
  SOR_RS09665 (SOR_1981) - 1952526..1953068 (+) 543 WP_000665079.1 TetR/AcrR family transcriptional regulator -
  SOR_RS09680 (SOR_1984) comE 1953311..1954057 (-) 747 WP_000866078.1 competence system response regulator transcription factor ComE Regulator
  SOR_RS09685 (SOR_1985) comD 1954054..1955373 (-) 1320 WP_000362884.1 competence system sensor histidine kinase ComD Regulator
  SOR_RS09690 (SOR_1986) comC/comC2 1955394..1955519 (-) 126 WP_000799678.1 competence-stimulating peptide ComC Regulator
  SOR_RS09700 (SOR_1989) rlmH 1955801..1956280 (-) 480 WP_000694219.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SOR_RS09705 (SOR_1990) htrA 1956466..1957662 (+) 1197 WP_000681803.1 S1C family serine protease Regulator
  SOR_RS09710 (SOR_1991) spo0J 1957720..1958478 (+) 759 WP_000410359.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 51237.18 Da        Isoelectric Point: 7.0077

>NTDB_id=40230 SOR_RS09685 WP_000362884.1 1954054..1955373(-) (comD) [Streptococcus oralis Uo5]
MDLFGLGIAIFYFIIISKSYEWICKINRKEQIVFFCYTCISVFTLEEIITLVFSNSFALSKFLFPLVVYLYLRKLKKSEK
YKSIFISLLLSLLYHSTHTFISVTLSSITGDEVVLHYKSTFLLVILLMTYFSILIIIRYFHLDIKYFDKDYLYPFLKKVI
VAFFGLHIVLFISDIVSTTHHLNSFGSILSTIVFICLLLIFFAMNSHKVQIEKEIALKQKKFEQKHLQTYTDEIVELYNE
IRGFRHDYAGMLVSMQMAIDSGDLQEINRVYNEVLVKANQKLRSEKYTYFDLNNIEDSALRSLIAQSIVYARKNDVEFTL
EVKDVITRLSMDLLDLVRIMSILLNNAVEGAADSYLKQMEVAVIKMDFETVIVIQNSCKITMTPSEDLFALGFSTKGRNR
GLGLNNVKEILDKYDNIILETEMEDNTFRQIIRFKREFE

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=40230 SOR_RS09685 WP_000362884.1 1954054..1955373(-) (comD) [Streptococcus oralis Uo5]
ATGGATTTATTTGGATTAGGGATAGCTATTTTTTATTTTATCATCATTAGCAAAAGTTATGAATGGATTTGTAAAATAAA
TAGAAAAGAACAAATTGTTTTTTTCTGTTACACATGTATCTCAGTTTTTACACTTGAAGAAATTATTACACTAGTATTTT
CTAATAGTTTTGCTTTGTCTAAATTTTTATTTCCTTTGGTTGTGTATCTTTATTTAAGAAAGTTAAAGAAGTCTGAAAAA
TACAAATCTATTTTTATCAGTCTACTATTGTCTTTATTATATCACAGTACTCATACTTTTATATCCGTAACTTTATCTTC
TATAACAGGAGATGAAGTAGTATTACACTATAAAAGTACATTCCTTTTAGTAATATTGTTGATGACTTATTTTTCTATTC
TAATAATAATCCGTTATTTTCATCTGGATATTAAATATTTTGATAAAGATTATCTGTACCCTTTTTTAAAAAAAGTAATA
GTTGCTTTCTTTGGTTTGCATATCGTATTGTTTATTTCAGATATAGTAAGTACAACTCATCATTTAAATAGCTTCGGAAG
TATTTTATCAACCATTGTTTTTATTTGCTTGTTATTGATTTTCTTTGCAATGAATTCTCACAAGGTTCAAATTGAAAAAG
AGATTGCTCTAAAACAAAAGAAATTTGAACAAAAGCATTTACAGACTTATACTGATGAAATTGTGGAGTTGTATAATGAA
ATTCGAGGTTTTCGTCATGATTATGCAGGGATGCTTGTCAGCATGCAAATGGCGATTGACAGTGGAGATTTACAAGAAAT
TAACAGGGTTTACAATGAAGTCTTAGTAAAAGCAAATCAGAAATTGAGGTCAGAAAAATATACTTACTTTGATTTAAATA
ATATAGAAGATTCTGCTTTACGAAGTTTAATTGCCCAATCGATTGTCTATGCACGAAAAAATGATGTAGAGTTTACATTG
GAAGTAAAAGATGTCATTACTAGATTGTCAATGGATTTACTTGATCTTGTTCGTATCATGAGCATTTTATTAAATAATGC
TGTTGAAGGTGCTGCAGATAGTTACTTGAAACAAATGGAAGTTGCAGTCATTAAAATGGATTTTGAAACAGTTATAGTTA
TCCAGAATTCATGCAAAATCACTATGACGCCTTCAGAGGATTTATTTGCCTTAGGTTTCTCTACCAAGGGAAGAAATAGA
GGTCTAGGACTTAATAATGTCAAAGAGATTTTAGATAAGTATGACAACATTATTTTAGAAACAGAGATGGAAGACAACAC
ATTTAGACAAATTATTAGATTTAAGAGGGAATTTGAATGA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(332-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GXK6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD Streptococcus mitis SK321

74.603

100

0.749
  comD Streptococcus mitis NCTC 12261

74.15

100

0.745
  comD/comD2 Streptococcus pneumoniae TIGR4

73.923

100

0.743
  comD/comD1 Streptococcus pneumoniae D39

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae R6

73.469

100

0.738
  comD/comD1 Streptococcus pneumoniae Rx1

73.469

100

0.738
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

50.267

85.194

0.428
  comD/comD2 Streptococcus gordonii strain NCTC7865

49.734

85.649

0.426

Multiple sequence alignment