Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACAV_RS17815 Genome accession   NC_015138
Coordinates   4074746..4075963 (+) Length   405 a.a.
NCBI ID   WP_013595978.1    Uniprot ID   F0QCL2
Organism   Paracidovorax avenae ATCC 19860     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4069746..4080963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAV_RS17790 (Acav_3592) rpmA 4070812..4071069 (-) 258 WP_013595975.1 50S ribosomal protein L27 -
  ACAV_RS17795 (Acav_3593) rplU 4071082..4071393 (-) 312 WP_011796717.1 50S ribosomal protein L21 -
  ACAV_RS17800 (Acav_3594) - 4071579..4072559 (+) 981 WP_013595976.1 polyprenyl synthetase family protein -
  ACAV_RS17810 (Acav_3595) pilB 4072978..4074714 (+) 1737 WP_013595977.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACAV_RS17815 (Acav_3596) pilC 4074746..4075963 (+) 1218 WP_013595978.1 type II secretion system F family protein Machinery gene
  ACAV_RS17820 (Acav_3597) - 4075963..4076850 (+) 888 WP_013595979.1 A24 family peptidase -
  ACAV_RS17825 (Acav_3598) coaE 4076847..4077473 (+) 627 WP_013595980.1 dephospho-CoA kinase -
  ACAV_RS17830 (Acav_3599) zapD 4077538..4078293 (+) 756 WP_041829314.1 cell division protein ZapD -
  ACAV_RS17835 (Acav_3600) - 4078320..4078574 (+) 255 WP_013595982.1 DNA gyrase inhibitor YacG -
  ACAV_RS17840 (Acav_3601) - 4078642..4079097 (-) 456 WP_013595983.1 NUDIX domain-containing protein -
  ACAV_RS17845 (Acav_3602) - 4079090..4079962 (-) 873 WP_013595984.1 ATP-binding protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44512.44 Da        Isoelectric Point: 9.2189

>NTDB_id=39875 ACAV_RS17815 WP_013595978.1 4074746..4075963(+) (pilC) [Paracidovorax avenae ATCC 19860]
MATAASRDIKDFVFEWEGKDRHGKVVRGEVRALGENQVQATLRRQGVLPTKIKKRRMRGGKKIKPKDIALFTRQMATMMK
AGVPLLQAFDIVGRGNTNASVTKLLNDIRADVETGTSLNAAFRKYPMYFDSLYCNLVEAGEAAGILEALLDRLALYMEKT
EAIKSKIRSALMYPTAVIIVAFVVVTVIMIFVIPAFKEVFTSFGADLPAPTLFVMGVSEIFVKWWWLIFGVLGGGAFFFM
QAWRRNEKMQMFMDRVLLRVPVFGALIDKSCVARWTRTLSTMFAAGVPLVEALDSVGGASGNSVYAMATERIQQEVSTGT
SLTAAMGNANVFPSMVIQMCAIGEESGSIDHMLGKAADFYEEEVDEMVAGLSSLMEPIIIVFLGTIIGGIVVSMYLPIFK
LGQVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=39875 ACAV_RS17815 WP_013595978.1 4074746..4075963(+) (pilC) [Paracidovorax avenae ATCC 19860]
ATGGCAACCGCTGCATCGAGGGACATCAAGGATTTCGTTTTCGAGTGGGAAGGCAAGGACCGCCACGGCAAGGTCGTGCG
CGGCGAGGTCCGGGCCCTGGGCGAGAACCAGGTCCAGGCGACGCTGCGCCGGCAGGGAGTGCTGCCCACCAAGATCAAGA
AGCGCCGCATGCGCGGCGGCAAGAAGATCAAGCCCAAGGACATCGCGCTCTTCACGCGGCAGATGGCCACGATGATGAAG
GCCGGGGTGCCCCTGCTGCAGGCCTTCGACATCGTGGGCCGCGGCAACACCAACGCGTCGGTCACCAAGCTGCTCAACGA
CATCCGCGCCGACGTGGAAACCGGTACGTCGCTGAATGCGGCCTTCCGCAAGTACCCGATGTATTTCGACAGCCTGTATT
GCAACCTGGTGGAAGCCGGGGAGGCCGCAGGTATCCTGGAAGCGCTGCTCGACCGGCTCGCGCTCTACATGGAGAAGACC
GAGGCCATCAAGTCGAAGATCCGCTCGGCGCTGATGTACCCGACGGCCGTGATCATCGTGGCCTTCGTCGTGGTCACCGT
CATCATGATCTTCGTGATCCCCGCGTTCAAGGAGGTGTTCACCTCGTTCGGCGCGGACCTGCCGGCGCCGACGCTGTTCG
TGATGGGCGTCAGCGAGATCTTCGTGAAATGGTGGTGGCTGATCTTCGGCGTGCTGGGCGGTGGCGCCTTCTTCTTCATG
CAGGCGTGGCGGCGCAACGAGAAGATGCAGATGTTCATGGACCGGGTGCTGCTGCGCGTTCCGGTCTTCGGCGCCCTGAT
CGACAAGTCCTGCGTGGCACGCTGGACCCGCACCCTCTCCACGATGTTCGCGGCGGGCGTTCCGCTGGTCGAGGCGCTGG
ATTCGGTGGGCGGCGCCTCGGGCAACTCGGTCTATGCCATGGCGACCGAAAGGATCCAGCAGGAAGTCTCCACCGGCACC
AGCCTGACGGCCGCGATGGGCAACGCGAACGTGTTCCCGTCCATGGTGATACAGATGTGCGCCATCGGCGAGGAGTCGGG
CTCGATCGACCACATGCTGGGCAAGGCGGCCGACTTCTACGAGGAAGAGGTCGATGAGATGGTCGCCGGGCTGTCGAGCC
TCATGGAGCCGATCATCATCGTGTTCCTGGGCACCATCATCGGCGGCATCGTGGTGTCGATGTACCTGCCCATCTTCAAG
CTGGGACAGGTGGTCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F0QCL2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

53.713

99.753

0.536
  pilG Neisseria gonorrhoeae MS11

50.877

98.519

0.501
  pilG Neisseria meningitidis 44/76-A

50.627

98.519

0.499
  pilC Legionella pneumophila strain ERS1305867

48.744

98.272

0.479
  pilC Acinetobacter baylyi ADP1

48.492

98.272

0.477
  pilC Acinetobacter baumannii D1279779

47.103

98.025

0.462
  pilC Vibrio cholerae strain A1552

39.798

98.025

0.39
  pilC Vibrio campbellii strain DS40M4

39

98.765

0.385
  pilC Thermus thermophilus HB27

38.095

98.519

0.375

Multiple sequence alignment