Detailed information    

insolico Bioinformatically predicted

Overview

Name   comC/comC2   Type   Regulator
Locus tag   INV104_RS11340 Genome accession   NC_017591
Coordinates   2139029..2139154 (-) Length   41 a.a.
NCBI ID   WP_000799686.1    Uniprot ID   P60242
Organism   Streptococcus pneumoniae INV104     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context

Location: 2134029..2144154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS14170 - 2134378..2135981 (-) 1604 Protein_2139 YhgE/Pip family protein -
  INV104_RS11315 (INV104_19360) - 2136160..2136702 (+) 543 WP_001158266.1 TetR/AcrR family transcriptional regulator -
  INV104_RS11330 (INV104_19370) comE 2136945..2137697 (-) 753 WP_000866065.1 competence system response regulator transcription factor ComE Regulator
  INV104_RS11335 (INV104_19380) comD 2137694..2139008 (-) 1315 Protein_2142 competence system sensor histidine kinase ComD -
  INV104_RS11340 (INV104_19390) comC/comC2 2139029..2139154 (-) 126 WP_000799686.1 competence-stimulating peptide ComC Regulator
  INV104_RS11350 (INV104_19400) rlmH 2139436..2139915 (-) 480 WP_000695929.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  INV104_RS11355 (INV104_19410) htrA 2140098..2141279 (+) 1182 WP_000681597.1 S1C family serine protease Regulator
  INV104_RS11360 (INV104_19420) spo0J 2141337..2142095 (+) 759 WP_000410378.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 41 a.a.        Molecular weight: 4907.00 Da        Isoelectric Point: 11.0006

>NTDB_id=39875 INV104_RS11340 WP_000799686.1 2139029..2139154(-) (comC/comC2) [Streptococcus pneumoniae INV104]
MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK

Nucleotide


Download         Length: 126 bp        

>NTDB_id=39875 INV104_RS11340 WP_000799686.1 2139029..2139154(-) (comC/comC2) [Streptococcus pneumoniae INV104]
ATGAAAAACACAGTTAAATTGGAACAGTTTGTAGCTTTGAAGGAAAAAGACTTACAAAAGATTAAAGGTGGGGAGATGAG
GATTTCAAGAATCATCCTTGATTTTCTTTTCCTACGAAAAAAGTAA

Domains

Predicted by InterProScan.

COMC family (ComC)

(1-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6CJ8
  PDB 6COO
  PDB 6COP
  PDB 6COQ
  PDB 6COR
  PDB 6COS
  PDB 6COW
  PDB 6OBW
  PDB 6OC2
  PDB 6OC4
  PDB 6OLD
  PDB 6V1N

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus pneumoniae A66

100

100

1
  comC/comC2 Streptococcus pneumoniae TIGR4

100

100

1
  comC/comC1 Streptococcus pneumoniae R6

80.488

100

0.805
  comC/comC1 Streptococcus pneumoniae G54

80.488

100

0.805
  comC/comC1 Streptococcus pneumoniae D39

80.488

100

0.805
  comC/comC1 Streptococcus pneumoniae Rx1

80.488

100

0.805
  comC Streptococcus mitis SK321

75.61

100

0.756
  comC Streptococcus mitis NCTC 12261

57.5

97.561

0.561

Multiple sequence alignment