Detailed information NTG0394657

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: GE021_RS09695
• Genome accession: NZ_CP053792
• Coordinates: 1984042..1984782 (-)
• Length: 246 a.a.
• NCBI ID: WP_003045484.1
• Uniprot ID: -
• Organism: Streptococcus canis strain HL_77_1
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1979042..1989782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GE021_RS09670 (GE021_009660)	-	1979391..1979663 (-)	273	WP_003045473.1	hypothetical protein	-
GE021_RS09675 (GE021_009665)	-	1979826..1981352 (+)	1527	WP_125075051.1	IS1182 family transposase	-
GE021_RS09680 (GE021_009670)	jag	1981427..1982335 (-)	909	WP_125074950.1	RNA-binding cell elongation regulator Jag/EloR	-
GE021_RS09685 (GE021_009675)	-	1982347..1983174 (-)	828	WP_125074951.1	YidC/Oxa1 family membrane protein insertase	-
GE021_RS09690 (GE021_009680)	rnpA	1983140..1983499 (-)	360	WP_125074952.1	ribonuclease P protein component	-
GE021_RS09695 (GE021_009685)	comE/blpR	1984042..1984782 (-)	741	WP_003045484.1	LytTR family DNA-binding domain-containing protein	Regulator
GE021_RS09700 (GE021_009690)	-	1984786..1986069 (-)	1284	WP_125074953.1	sensor histidine kinase	-
GE021_RS09705 (GE021_009695)	-	1986070..1987413 (-)	1344	WP_125074954.1	GHKL domain-containing protein	-
GE021_RS09710 (GE021_009700)	gltX	1987918..1989366 (-)	1449	WP_125074955.1	glutamate--tRNA ligase	-

Sequence

Protein

• Length: 246 a.a.
• Molecular weight: 28893.27 Da
• Isoelectric Point: 4.9564

>NTDB_id=394657 GE021_RS09695 WP_003045484.1 1984042..1984782(-) (comE/blpR) [Streptococcus canis strain HL_77_1]
MMNIFILEDDFIQQTRIESVVVAILEATKIPCNQLEVFSNPQKLFESIQERGDHQLYFLDIEIGDEARRGLELAVDIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAADKEQFKEQIEDCIRYTYEMMSSRESEDIFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDRVVRIDKAKQLLYFENGDSCMVSRLKMKCLFE
KWESLH

Nucleotide

• Length: 741 bp

>NTDB_id=394657 GE021_RS09695 WP_003045484.1 1984042..1984782(-) (comE/blpR) [Streptococcus canis strain HL_77_1]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATCCAGCAGACACGCATTGAGTCCGTGGTGGTGGCTATCTTGGAAGC
AACTAAAATCCCTTGTAATCAGCTAGAAGTATTTTCAAATCCCCAAAAATTATTTGAGAGCATTCAAGAAAGAGGAGACC
ATCAACTGTATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGTGGCCTTGAGTTAGCAGTAGATATCCGCCAAAAA
GATCCCAATGCAGTGATTGTTTTTGTGACCACTCATTCTGAATTTGCACCTATTTCCTTCAAATATAAGGTTTCTGCTCT
GGATTTTATTGACAAGGCGGCGGATAAGGAGCAGTTCAAGGAACAAATTGAAGACTGTATCCGCTACACCTATGAGATGA
TGTCAAGTCGGGAATCTGAAGATATATTTTTGTTTGAAACGCCCCAGACCAGATTAAAGCTACCTTACAAAGATATTTTA
TACTTTGCCACAGCAACTACGCCCCACAAGGTGTGTTTGTGGACTCAGACGGAGAGACTGGAATTCTATGGTAATTTATC
TGAAATACAGGCCGTTGCTCCTAAGCTTTTCTTATGTCATAGGTCCTACTTGGTCAATCTTGATAGGGTTGTCCGCATTG
ACAAGGCCAAGCAGCTGCTTTATTTTGAAAATGGGGATTCCTGCATGGTTTCACGTTTGAAAATGAAATGCCTTTTTGAA
AAATGGGAGTCCCTTCATTAA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-242)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	48.117	97.154	0.467
comE/comE1	Streptococcus equinus JB1	42.437	96.748	0.411
comE/comE2	Streptococcus equinus JB1	40.408	99.593	0.402
comE/comE2	Streptococcus gordonii strain NCTC7865	38.934	99.187	0.386
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.934	99.187	0.386
comE	Streptococcus mitis NCTC 12261	36.929	97.967	0.362
comE	Streptococcus pneumoniae Rx1	36.929	97.967	0.362
comE	Streptococcus pneumoniae D39	36.929	97.967	0.362
comE	Streptococcus pneumoniae R6	36.929	97.967	0.362
comE	Streptococcus pneumoniae TIGR4	36.929	97.967	0.362
comE	Streptococcus mitis SK321	36.929	97.967	0.362