Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CWC22_RS17205 Genome accession   NZ_CP045429
Coordinates   4008602..4009834 (+) Length   410 a.a.
NCBI ID   WP_125559031.1    Uniprot ID   A0A5S3UT29
Organism   Pseudoalteromonas rubra strain S4059     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4003602..4014834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWC22_RS17185 (CWC22_017110) ampE 4005226..4006110 (-) 885 WP_138539316.1 beta-lactamase regulator AmpE -
  CWC22_RS17190 (CWC22_017115) ampD 4006122..4006658 (-) 537 WP_138539315.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  CWC22_RS17195 (CWC22_017120) nadC 4006848..4007687 (+) 840 WP_138539314.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CWC22_RS24600 (CWC22_017125) - 4008085..4008552 (+) 468 WP_138539313.1 pilin -
  CWC22_RS17205 (CWC22_017130) pilC 4008602..4009834 (+) 1233 WP_125559031.1 type II secretion system F family protein Machinery gene
  CWC22_RS17210 (CWC22_017135) pilD 4009857..4010732 (+) 876 WP_125559029.1 prepilin peptidase Machinery gene
  CWC22_RS17215 (CWC22_017140) coaE 4010737..4011348 (+) 612 WP_138539312.1 dephospho-CoA kinase -
  CWC22_RS17220 (CWC22_017145) pilB 4011457..4013133 (+) 1677 WP_125559025.1 type IV-A pilus assembly ATPase PilB Machinery gene
  CWC22_RS17225 (CWC22_017150) yacG 4013205..4013447 (+) 243 WP_010383557.1 DNA gyrase inhibitor YacG -
  CWC22_RS17230 (CWC22_017155) - 4013494..4014003 (-) 510 WP_138539311.1 Spy/CpxP family protein refolding chaperone -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 44521.31 Da        Isoelectric Point: 9.7821

>NTDB_id=394067 CWC22_RS17205 WP_125559031.1 4008602..4009834(+) (pilC) [Pseudoalteromonas rubra strain S4059]
MNQPDKNSAKVDTFIWVGVSARGKRLQGELTGTSVALVKAQLRKQGITPSKVKRKPKPLFGFSSTQKITPKDIAVVTRQI
ATMLTAGVALVQALDMIASGAKNKSLSKLITHIADEVKAGQPLAKSLRSHPRYFDELYCDLVESGEQSGALDRIFDRVAL
YKEKAEALKSKIKKAMFYPIAVLSVALIVTSILLIFVVPQFEEIFTGFGAELPGFTLMVLGISEFMQEYWWLFLIGLGGA
GYAYKEALQRSPAVRHFNDRMVLRIPAIGEILKKAAVARYARTLSTTFAAGVPLVNALDSAAGASGNIIYKNAILDIKGE
VSSGNQMNWAMRNARIFPDMVVQMVSIGEESGALDSMLAKVASIYEQEVDDAVDGLSSLLEPMIMVILGVLVGGLIIAMY
LPIFQLGTVI

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=394067 CWC22_RS17205 WP_125559031.1 4008602..4009834(+) (pilC) [Pseudoalteromonas rubra strain S4059]
ATGAACCAACCCGACAAAAACTCTGCCAAAGTCGATACTTTTATCTGGGTCGGCGTTAGCGCCCGTGGTAAACGTTTACA
AGGCGAACTAACTGGCACCAGTGTGGCCCTGGTCAAAGCGCAACTGCGCAAGCAAGGGATCACGCCATCTAAAGTAAAGC
GCAAGCCTAAACCCCTATTCGGGTTCAGTAGCACACAAAAAATTACCCCAAAAGACATCGCCGTTGTGACCCGGCAAATT
GCCACTATGCTGACTGCTGGTGTGGCTCTGGTACAGGCGTTGGATATGATTGCCTCAGGTGCCAAAAATAAAAGCCTCAG
CAAGCTTATCACGCACATTGCCGACGAAGTCAAAGCAGGCCAACCGCTGGCCAAGTCCCTGCGTAGCCACCCGAGATATT
TTGACGAATTATATTGCGACCTGGTTGAATCTGGCGAGCAGTCGGGTGCGTTGGACCGCATCTTTGACAGAGTAGCGCTG
TATAAAGAAAAAGCAGAAGCACTCAAGTCTAAGATCAAAAAAGCAATGTTTTACCCAATAGCTGTACTTTCTGTCGCCCT
GATCGTGACCTCCATATTATTGATTTTTGTGGTCCCGCAATTTGAAGAGATTTTCACCGGATTTGGCGCTGAATTACCAG
GCTTTACACTGATGGTACTGGGCATTTCTGAGTTTATGCAGGAATACTGGTGGCTGTTTCTTATTGGCCTGGGTGGCGCA
GGCTATGCCTACAAAGAAGCACTGCAACGTAGTCCTGCCGTTCGCCACTTTAACGATCGAATGGTACTGCGGATCCCGGC
GATTGGCGAAATCCTGAAAAAAGCCGCCGTTGCCCGCTATGCTAGAACGTTATCGACTACCTTTGCAGCAGGTGTTCCTT
TGGTCAATGCGCTGGATTCAGCCGCTGGCGCTTCCGGCAATATCATCTATAAAAATGCGATTTTGGATATTAAGGGTGAA
GTCAGCTCAGGTAACCAAATGAACTGGGCGATGCGCAACGCCAGAATTTTTCCCGATATGGTAGTGCAAATGGTCTCCAT
AGGGGAAGAATCAGGTGCACTGGACAGTATGCTGGCCAAAGTCGCCAGTATTTATGAGCAGGAAGTGGATGATGCAGTCG
ATGGACTATCTTCATTGCTTGAGCCTATGATCATGGTGATCCTGGGTGTGCTGGTTGGTGGCTTGATTATTGCCATGTAT
TTACCTATATTCCAGCTCGGCACCGTCATTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(281-402)

Type II secretion system (T2SS), protein F (T2SSF)

(77-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S3UT29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

60.349

97.805

0.59
  pilC Legionella pneumophila strain ERS1305867

55.665

99.024

0.551
  pilC Acinetobacter baylyi ADP1

52.593

98.78

0.52
  pilC Acinetobacter baumannii D1279779

51.852

98.78

0.512
  pilC Vibrio campbellii strain DS40M4

43.457

98.78

0.429
  pilG Neisseria gonorrhoeae MS11

43.781

98.049

0.429
  pilC Vibrio cholerae strain A1552

43.75

97.561

0.427
  pilG Neisseria meningitidis 44/76-A

43.532

98.049

0.427

Multiple sequence alignment