Detailed information NTG0390447

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: FSA28_RS07280
• Genome accession: NZ_CP044495
• Coordinates: 1476887..1477768 (-)
• Length: 293 a.a.
• NCBI ID: WP_002291068.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain UA140
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1471887..1482768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA28_RS07255 (FSA28_1219)	vicR	1472781..1473488 (-)	708	WP_002262930.1	response regulator YycF	Regulator
FSA28_RS07260 (FSA28_1220)	-	1473841..1474623 (+)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
FSA28_RS07265 (FSA28_1221)	-	1474620..1475432 (+)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
FSA28_RS07270 (FSA28_1222)	-	1475450..1476154 (+)	705	WP_002262933.1	amino acid ABC transporter permease	-
FSA28_RS07275 (FSA28_1223)	-	1476169..1476819 (+)	651	WP_002262934.1	amino acid ABC transporter permease	-
FSA28_RS07280 (FSA28_1224)	endA	1476887..1477768 (-)	882	WP_002291068.1	DNA/RNA non-specific endonuclease	Machinery gene
FSA28_RS07285 (FSA28_1225)	-	1477810..1477998 (-)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
FSA28_RS07290 (FSA28_1226)	murA	1478001..1479272 (-)	1272	WP_002273074.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
FSA28_RS07295 (FSA28_1227)	-	1479338..1479571 (-)	234	WP_002285829.1	DUF1146 family protein	-
FSA28_RS07300 (FSA28_1228)	-	1479843..1480259 (-)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
FSA28_RS07305 (FSA28_1229)	atpD	1480273..1481679 (-)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
FSA28_RS07310 (FSA28_1230)	-	1481705..1482583 (-)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32176.81 Da
• Isoelectric Point: 9.5337

>NTDB_id=390447 FSA28_RS07280 WP_002291068.1 1476887..1477768(-) (endA) [Streptococcus mutans strain UA140]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQVAQLLTGKNKDMLSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=390447 FSA28_RS07280 WP_002291068.1 1476887..1477768(-) (endA) [Streptococcus mutans strain UA140]
ATGACTAGAAAAACGAATAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGTTGCCCAATTATTGACAGGTAAAA
ACAAGGATATGCTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCCTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGCCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCCA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCGGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512