Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   FSA40_RS09820 Genome accession   NZ_CP044493
Coordinates   1934131..1935387 (-) Length   418 a.a.
NCBI ID   WP_151416454.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1929131..1940387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS09775 (FSA40_1960) - 1929324..1929623 (-) 300 WP_151416453.1 DUF1292 domain-containing protein -
  FSA40_RS09780 (FSA40_1961) ruvX 1929704..1930123 (-) 420 WP_002262385.1 Holliday junction resolvase RuvX -
  FSA40_RS09785 (FSA40_1962) - 1930120..1930389 (-) 270 WP_002262386.1 IreB family regulatory phosphoprotein -
  FSA40_RS09790 (FSA40_1963) brsR 1930557..1930991 (+) 435 WP_002266979.1 bacteriocin genes transcriptional regulator BrsR Regulator
  FSA40_RS09795 (FSA40_1964) brsM 1931004..1931450 (+) 447 WP_002262388.1 bacteriocin genes regulator BrsM Regulator
  FSA40_RS09800 (FSA40_1965) - 1931441..1931653 (-) 213 WP_002262389.1 hypothetical protein -
  FSA40_RS09805 (FSA40_1966) - 1931780..1932205 (-) 426 WP_002269684.1 hypothetical protein -
  FSA40_RS09810 (FSA40_1967) spx 1932457..1932855 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FSA40_RS09815 (FSA40_1968) recA 1932940..1934091 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FSA40_RS09820 (FSA40_1969) cinA 1934131..1935387 (-) 1257 WP_151416454.1 competence/damage-inducible protein A Machinery gene
  FSA40_RS09825 (FSA40_1970) - 1935536..1936096 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  FSA40_RS09830 (FSA40_1971) ruvA 1936178..1936771 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA -
  FSA40_RS09835 (FSA40_1972) mutL 1936954..1938909 (-) 1956 WP_002268465.1 DNA mismatch repair endonuclease MutL -
  FSA40_RS09840 - 1939134..1939412 (+) 279 Protein_1838 transposase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45746.56 Da        Isoelectric Point: 6.2714

>NTDB_id=390411 FSA40_RS09820 WP_151416454.1 1934131..1935387(-) (cinA) [Streptococcus mutans strain MD]
MKSEIIAVGTEILTGQIVNTNSQFLSEKFAELGIDVYFQTAVGDNEERLLSVLKIAKERSDLIVLCGGLGPTEDDLTKQT
LAKFLKRELVFDKTAQERLDEFFASRPTSMRTPNNECQAQIIAGSQPLSNKTGLAVGGLLEADGVTYVVLPGPPSELKPM
VNKELLPYLSKTSEKLYSRVLRFFGIGESHLVTLLHDLIAEQTDPTIAPYAKTGEVTIRLSTKVHRQKEADSKLDKLEKK
IITIDNLADYFYGYGEENSLPQVVFDLLKEKGKTITAAESLTAGLFQARLADFAGASDIFKGGFITYSIEEKARMLGIPF
EDLQLHGVVSAFTAEKMAERSRQLTQADLAVSLTGVAGPDSLEGQPAGTVFIGLSSSKRTMAIKVLIGGRSRSDVRYIAV
LHAFNLVRQTLLSHKNLV

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=390411 FSA40_RS09820 WP_151416454.1 1934131..1935387(-) (cinA) [Streptococcus mutans strain MD]
ATGAAATCTGAGATCATTGCTGTTGGAACAGAAATTTTAACAGGACAAATTGTTAATACTAATAGTCAATTTTTATCAGA
AAAATTCGCAGAATTAGGAATTGATGTTTATTTTCAAACAGCAGTTGGTGATAATGAAGAACGCCTTTTATCTGTTTTGA
AAATTGCAAAGGAACGTAGTGATTTAATCGTACTTTGCGGTGGTTTGGGACCAACAGAAGATGATTTAACAAAACAAACC
CTAGCAAAATTTTTGAAAAGAGAATTGGTATTTGATAAAACAGCTCAAGAACGTCTAGATGAATTTTTTGCATCACGTCC
AACATCTATGCGCACGCCAAATAATGAATGTCAGGCGCAGATTATAGCAGGAAGTCAGCCTTTATCTAATAAAACAGGCT
TAGCAGTTGGGGGGCTTTTGGAGGCAGATGGAGTGACTTATGTTGTATTACCTGGTCCGCCTAGCGAATTGAAGCCTATG
GTTAACAAAGAGTTACTCCCTTATTTATCAAAAACTTCTGAGAAGCTTTATTCTCGTGTGTTACGCTTTTTTGGTATTGG
TGAGAGTCATCTAGTGACCTTGTTGCATGACTTAATAGCGGAGCAAACAGATCCCACAATTGCTCCTTATGCTAAGACAG
GCGAGGTAACAATACGTTTATCAACAAAAGTCCATAGGCAGAAAGAAGCAGATAGTAAGTTAGATAAGTTGGAAAAGAAA
ATTATAACTATTGATAACTTGGCTGATTATTTTTATGGTTATGGTGAAGAAAATTCATTACCACAGGTTGTATTTGATCT
GCTTAAGGAAAAGGGTAAAACGATTACAGCAGCTGAAAGTTTAACAGCAGGCCTTTTTCAGGCAAGATTAGCAGATTTTG
CAGGAGCATCTGATATCTTTAAGGGAGGTTTTATAACTTACAGTATAGAAGAGAAGGCTAGAATGCTAGGTATTCCCTTT
GAAGATCTCCAACTTCATGGGGTTGTTAGTGCTTTTACTGCTGAAAAGATGGCAGAGCGCTCCCGCCAGCTGACTCAAGC
AGATTTGGCTGTTTCTTTAACAGGAGTTGCAGGTCCGGATAGCTTAGAAGGTCAGCCGGCAGGGACAGTTTTTATCGGTT
TGTCAAGTTCCAAAAGAACAATGGCAATCAAAGTGTTAATTGGCGGACGCAGTCGGTCTGATGTGCGTTATATCGCTGTT
TTACATGCTTTTAATTTAGTACGTCAAACTTTATTATCTCATAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(259-411)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

99.522

100

0.995
  cinA Streptococcus mitis SK321

72.01

100

0.72
  cinA Streptococcus mitis NCTC 12261

71.531

100

0.715
  cinA Streptococcus pneumoniae TIGR4

70.335

100

0.703
  cinA Streptococcus pneumoniae Rx1

70.096

100

0.701
  cinA Streptococcus pneumoniae R6

70.096

100

0.701
  cinA Streptococcus pneumoniae D39

69.856

100

0.699
  cinA Streptococcus suis isolate S10

55.231

98.325

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.763

98.804

0.452

Multiple sequence alignment