Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   HKM25_RS05500 Genome accession   NZ_CP053210
Coordinates   1096704..1097168 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 6A-10     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1091704..1102168
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HKM25_RS05480 (HKM25_1119) - 1092655..1093623 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  HKM25_RS05485 (HKM25_1120) pdrM 1093777..1095138 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  HKM25_RS05490 - 1095149..1095409 (-) 261 WP_001105925.1 hypothetical protein -
  HKM25_RS05495 (HKM25_1121) - 1095423..1096691 (-) 1269 WP_000924490.1 dihydroorotase -
  HKM25_RS05500 (HKM25_1122) mutX 1096704..1097168 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  HKM25_RS05505 (HKM25_1123) - 1097178..1097831 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  HKM25_RS05510 (HKM25_1124) - 1097969..1098571 (-) 603 WP_001809695.1 hypothetical protein -
  HKM25_RS05515 (HKM25_1125) - 1098629..1099342 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  HKM25_RS05520 (HKM25_1126) - 1099904..1101249 (+) 1346 Protein_1105 IS1380-like element ISSpn5 family transposase -
  HKM25_RS05525 (HKM25_1127) dhaM 1101508..1101888 (-) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  HKM25_RS12060 - 1101888..1101962 (-) 75 Protein_1107 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=390410 HKM25_RS05500 WP_001135768.1 1096704..1097168(-) (mutX) [Streptococcus pneumoniae strain 6A-10]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=390410 HKM25_RS05500 WP_001135768.1 1096704..1097168(-) (mutX) [Streptococcus pneumoniae strain 6A-10]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment